Lingchong You

Image of Lingchong You

Paul Ruffin Scarborough Associate Professor of Engineering

Dr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.

Appointments and Affiliations
  • Paul Ruffin Scarborough Associate Professor of Engineering
  • Associate Professor of Biomedical Engineering
Contact Information:
Education:

  • Ph.D. University of Wisconsin at Madison, 2002
  • B.S.E. Chengdu University of Science and Technology (China), 1994
  • M.S. University of Science and Technology of China (China), 0199

Curriculum Vitae
Research Interests:

Dr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.

Specialties:

Genomics
Computational Biology
Nonlinear Dynamics

Awards, Honors, and Distinctions:

  • Fellowships for Science and Engineering. David and Lucile Packard Foundation. 2006

Courses Taught:
  • BME 260L: Modeling Cellular and Molecular Systems
  • BME 394: Projects in Biomedical Engineering (GE)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 574: Modeling and Engineering Gene Circuits (GE, MC)
  • BME 791: Graduate Independent Study
  • BME 899: Special Readings in Biomedical Engineering
  • CBB 574: Modeling and Engineering Gene Circuits (GE, MC)
  • EGR 391: Projects in Engineering

Representative Publications: (More Publications)
    • Pai, A; Srimani, JK; Tanouchi, Y; You, L, Generic metric to quantify quorum sensing activation dynamics., ACS Synthetic Biology, vol 3 no. 4 (2014), pp. 220-227 [10.1021/sb400069w] [abs].
    • Lee, AJ; You, L, Cell biology. Cells listen to their inner voice., Science, vol 343 no. 6171 (2014), pp. 624-625 [10.1126/science.1250244] [abs].
    • Smith, R; Tan, C; Srimani, JK; Pai, A; Riccione, KA; Song, H; You, L, Programmed Allee effect in bacteria causes a tradeoff between population spread and survival., Proceedings of the National Academy of Sciences of USA, vol 111 no. 5 (2014), pp. 1969-1974 [10.1073/pnas.1315954111] [abs].
    • Dong, P; Maddali, MV; Srimani, JK; Thélot, F; Nevins, JR; Mathey-Prevot, B; You, L, Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control., Nature Communications, vol 5 (2014) [10.1038/ncomms5750] [abs].
    • Shats, I; Gatza, ML; Liu, B; Angus, SP; You, L; Nevins, JR, FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function., Cancer Research, vol 73 no. 19 (2013), pp. 6056-6067 [10.1158/0008-5472.CAN-13-0453] [abs].