George A. Truskey

Research Themes

Biomechanics & Mechanobiology, Computational Modeling of Biological Systems, Tissue Engineering & Regenerative Medicine

Research Interests

Cardiovascular tissue engineering, mechanisms of atherogenesis, cell adhesion, and cell biomechanics.

Bio

My research interests focus upon the effect of physical forces on the function of vascular cells and skeletal muscle, cell adhesion, and the design of engineered tissues.  Current research projects examine the  effect of endothelial cell senescence upon permeability to macromolecules and the response to fluid shear stress, the development of microphysiological blood vessels and muscles for evaluation of drug toxicity and the design of engineered endothelialized blood vessels and skeletal muscle bundles.

Education

• B.S.E. University of Pennsylvania, 1979
• Ph.D. Massachusetts Institute of Technology, 1985

Positions

• R. Eugene and Susie E. Goodson Distinguished Professor of Biomedical Engineering
• Professor of Biomedical Engineering
• Affiliate of the Duke Regeneration Center
• Affiliate of the Duke Initiative for Science & Society

Awards, Honors, and Distinctions

• AAAS Fellow. American Association for the Advancement of Science. 2014
• BMES Distinguished Service Award. Biomedical Engineering Society. 2012
• NIH CSR College of Reviewers. NIH. 2010
• Capers and Marion McDonald Award for Excellence in Mentoring and Advising. Duke University. 2007
• Fellow. Biomedical Engineering Society. 2006
• Fellow. American Institute for Medical and Biological Engineering. 1999
• Fellow. Council on Arteriosclerosis, Thrombosis and Vascular Biology, American Heart Association. 1999
• Excellence in Teaching Award. Tau Beta Pi, North Carolina Gamma Chapter. 1998
• Outstanding Scientific Paper in the Journal of Parenteral Science and Technology. Parenteral Drug Association. 1987

Courses Taught

• EGR 393: Research Projects in Engineering
• BME 792: Continuation of Graduate Independent Study
• BME 791: Graduate Independent Study
• BME 590: Special Topics in Biomedical Engineering
• BME 566: Transport Phenomena in Cells and Organs (GE, MC)
• BME 494: Projects in Biomedical Engineering (GE)
• BME 493: Projects in Biomedical Engineering (GE)
• BME 493-1: Projects in Biomedical Engineering (GE)
• BME 394: Projects in Biomedical Engineering (GE)

Publications

• Vakili S, Izydore EK, Losert L, Cabral WA, Tavarez UL, Shores K, et al. Angiopoietin-2 reverses endothelial cell dysfunction in progeria vasculature. Aging cell. 2024 Oct;e14375.
• Covert LT, Osman A, Truskey GA. Interferon-β-Induced Injury During Pediatric Muscle Differentiation: Insight Into Juvenile Dermatomyositis Pathogenesis. ACR open rheumatology. 2024 Oct;
• Covert LT, Prinz JA, Swain-Lenz D, Dvergsten J, Truskey GA. Genetic changes from type I interferons and JAK inhibitors: clues to drivers of juvenile dermatomyositis. Rheumatology (Oxford). 2024 Sep 1;63(SI2):SI240–8.
• Lopez I, Truskey GA. Multi-cellular engineered living systems to assess reproductive toxicology. Reproductive toxicology (Elmsford, NY). 2024 Aug;127:108609.
• Khodabukus A, Prabhu NK, Roberts T, Buldo M, Detwiler A, Fralish ZD, et al. Bioengineered Model of Human LGMD2B Skeletal Muscle Reveals Roles of Intracellular Calcium Overload in Contractile and Metabolic Dysfunction in Dysferlinopathy. Adv Sci (Weinh). 2024 Aug;11(31):e2400188.
• Mishra S, Welch N, Singh SS, Singh KD, Bellar A, Kumar A, et al. Ammonia transporter RhBG initiates downstream signaling and functional responses by activating NFκB. Proceedings of the National Academy of Sciences of the United States of America. 2024 Jul;121(31):e2314760121.
• Covert LT, Patel H, Osman A, Duncan L, Dvergsten J, Truskey GA. Effect of type I interferon on engineered pediatric skeletal muscle: a promising model for juvenile dermatomyositis. Rheumatology (Oxford). 2024 Jan 4;63(1):209–17.
• Shores KL, Truskey GA. Mechanotransduction of the vasculature in Hutchinson-Gilford Progeria Syndrome. Frontiers in physiology. 2024 Jan;15:1464678.
• Lee JH, Shores KL, Breithaupt JJ, Lee CS, Fodera DM, Kwon JB, et al. PCSK9 activation promotes early atherosclerosis in a vascular microphysiological system. APL bioengineering. 2023 Dec;7(4):046103.
• Truskey GA. The Potential of Deep Learning to Advance Clinical Applications of Computational Biomechanics. Bioengineering (Basel, Switzerland). 2023 Sep;10(9):1066.
• Zhang Q, Zhan R-Z, Patsy M, Li B, Chen Y, Lipes BD, et al. Differential Response of Engineered Human Cardiac Tissues to Delta and Omicron COVID-19 Virus. J Am Heart Assoc. 2023 Jun 20;12(12):e029390.
• Abutaleb NO, Atchison L, Choi L, Bedapudi A, Shores K, Gete Y, et al. Lonafarnib and everolimus reduce pathology in iPSC-derived tissue engineered blood vessel model of Hutchinson-Gilford Progeria Syndrome. Scientific reports. 2023 Mar;13(1):5032.
• Covert LT, Patel H, Osman A, Dvergsten J, Truskey GA. EFFECT OF TYPE I INTERFERON ON ENGINEERED HUMAN SKELETAL MUSCLE: A PROMISING MODEL FOR JUVENILE DERMATOMYOSITIS. In: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2023. p. 414–5.
• Torres MJ, Zhang X, Slentz DH, Koves TR, Patel H, Truskey GA, et al. Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities. iScience. 2022 Oct 21;25(10):105189.
• Bishawi M, Lee FH, Abraham DM, Glass C, Blocker SJ, Cox DJ, et al. Late onset cardiovascular dysfunction in adult mice resulting from galactic cosmic ray exposure. iScience. 2022 Apr 15;25(4):104086.
• Aydin O, Passaro AP, Raman R, Spellicy SE, Weinberg RP, Kamm RD, et al. Principles for the design of multicellular engineered living systems. APL bioengineering. 2022 Mar;6(1):010903.
• Oliver CE, Patel H, Hong J, Carter J, Kraus WE, Huffman KM, et al. Tissue engineered skeletal muscle model of rheumatoid arthritis using human primary skeletal muscle cells. J Tissue Eng Regen Med. 2022 Feb;16(2):128–39.
• Bishawi M, Kaplan M, Chidyagwai S, Cappiello J, Cherry A, MacLeod D, et al. Patient- and Ventilator-Specific Modeling to Drive the Use and Development of 3D Printed Devices for Rapid Ventilator Splitting During the COVID-19 Pandemic. In: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 2022. p. 137–49.
• Truskey G, Jones E, Shah S, McGarrah R. ASSESSING THE ROLE OF BRANCHED CHAIN AMINO ACIDS IN ATHEROSCLEROSIS USING A HUMAN VASCULAR MICROPHYSIOLOGICAL SYSTEM. In: TISSUE ENGINEERING PART A. 2022. p. S570–S570.
• Truskey G, Ananthakumar A. MODELING SKELETAL MUSCLE FIBROSIS USING A HUMAN MICROPHYSIOLOGICAL SYSTEM. In: TISSUE ENGINEERING PART A. 2022. p. S570–1.
• Zhang X, Abutaleb NO, Salmon E, Truskey GA. In Situ Fabrication and Perfusion of Tissue-Engineered Blood Vessel Microphysiological System. Methods in molecular biology (Clifton, NJ). 2022 Jan;2375:77–90.
• Vann CG, Zhang X, Khodabukus A, Orenduff MC, Chen Y-H, Corcoran DL, et al. Differential microRNA profiles of intramuscular and secreted extracellular vesicles in human tissue-engineered muscle. Front Physiol. 2022;13:937899.
• Zhang Q, Bosch-Rué È, Pérez RA, Truskey GA. Biofabrication of tissue engineering vascular systems. APL bioengineering. 2021 Jun;5(2):021507.
• Abutaleb NO, Truskey GA. Differentiation and characterization of human iPSC-derived vascular endothelial cells under physiological shear stress. STAR protocols. 2021 Jun;2(2):100394.
• Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, et al. The NIH Somatic Cell Genome Editing program. Nature. 2021 Apr;592(7853):195–204.
• Lee JH, Chen Z, He S, Zhou J, Tsai A, Truskey G, et al. Emulating Early Atherosclerosis in a Vascular Microphysiological System Using Branched Tissue-Engineered Blood Vessels. Advanced biology. 2021 Apr;5(4):e2000428.
• Kennedy CC, Brown EE, Abutaleb NO, Truskey GA. Development and Application of Endothelial Cells Derived From Pluripotent Stem Cells in Microphysiological Systems Models. Frontiers in cardiovascular medicine. 2021 Jan;8:625016.
• Kondash ME, Ananthakumar A, Khodabukus A, Bursac N, Truskey GA. Glucose Uptake and Insulin Response in Tissue-engineered Human Skeletal Muscle. Tissue engineering and regenerative medicine. 2020 Dec;17(6):801–13.
• Zhang X, Bishawi M, Zhang G, Prasad V, Salmon E, Breithaupt JJ, et al. Modeling early stage atherosclerosis in a primary human vascular microphysiological system. Nature communications. 2020 Oct;11(1):5426.
• Sklivas AB, Goss D, Bursac N, Khodahukus A, Koves T, Muoio D, et al. Gene Expression Differences In Three-dimensional Myobundles Compared To Two-dimensional Myocultures. Medicine & Science in Sports & Exercise. 2020 Jul;52(7S):781–2.
• Salmon EE, Breithaupt JJ, Truskey GA. Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation. Cells. 2020 May;9(5):E1292.
• Truskey GA, Fu J. The future of biomedical engineering: Bioengineering of organoids and tissue development. Current Opinion in Biomedical Engineering. 2020 Mar 1;13:A1–2.
• Atchison L, Abutaleb NO, Snyder-Mounts E, Gete Y, Ladha A, Ribar T, et al. iPSC-Derived Endothelial Cells Affect Vascular Function in a Tissue-Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome. Stem cell reports. 2020 Feb;14(2):325–37.
• Abutaleb NO, Truskey GA. Human iPSCs Stretch to Improve Tissue-Engineered Vascular Grafts. Cell stem cell. 2020 Feb;26(2):136–7.
• Zhang X, Truskey GA. A novel in situ monitoring system of 3D engineered muscle. In: 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. 2020. p. 1037–8.
• Sklivas AB, Goss DII, Bursac N, Khodahukus A, Koves T, Muoio D, et al. Gene Expression Differences In Three-dimensional Myobundles Compared To Two-dimensional Myocultures. In: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2020. p. 781–2.
• Ananthakumar A, Liu Y, Fernandez CE, Truskey GA, Voora D. Modeling statin myopathy in a human skeletal muscle microphysiological system. PLoS One. 2020;15(11):e0242422.
• Rhim C, E. Kraus W, A. Truskey G. Biomechanical effects on microRNA expression in skeletal muscle differentiation. AIMS Bioengineering. 2020;7(3):147–64.
• Davis BNJ, Santoso JW, Walker MJ, Oliver CE, Cunningham MM, Boehm CA, et al. Modeling the Effect of TNF-α upon Drug-Induced Toxicity in Human, Tissue-Engineered Myobundles. Ann Biomed Eng. 2019 Jul;47(7):1596–610.
• Lin L, Xu H, Bishawi M, Feng F, Samy K, Truskey G, et al. Circulating mitochondria in organ donors promote allograft rejection. Am J Transplant. 2019 Jul;19(7):1917–29.
• Davis BN, Yen R, Prasad V, Truskey GA. Oxygen consumption in human, tissue-engineered myobundles during basal and electrical stimulation conditions. APL bioengineering. 2019 Jun;3(2):026103.
• Torres Alcalde MJ, Zang X, Slentz DH, Koves TR, Truskey GA, Muoio DM. Abstract P284: The Chemotherapeutic Agent Docetaxel Disrupts Mitochondrial Energetics in 3D Human Bioengineered Myobundles. In: Circulation. Ovid Technologies (Wolters Kluwer Health); 2019.
• Truskey GA. The future of biomedical engineering — digital health. Current Opinion in Biomedical Engineering. 2019 Mar 1;9:A1–2.
• Liu Y, Ananthakumar A, Thompson W, Myers R, Kaddurah-Daouk R, Dubois L, et al. Metabolomic Profiling of Engineered Skeletal Myobundles Identifies a Plasma Biomarker for Statin Associated Musculoskeletal Symptoms (SAMS). In: CIRCULATION. 2019.
• Breithaupt JJ, Kwon J, Ettyreddy A, Zhang X, Gersbach C, Truskey GA. PCSK9 Knockdown Decreases Inflammatory Markers and U937 Monocyte Accumulation in a Tissue-Engineered Blood Vessel Model. In: CIRCULATION. 2019.
• Truskey GA. Development and application of human skeletal muscle microphysiological systems. Lab on a chip. 2018 Oct;18(20):3061–73.
• Zhang X, Hong S, Yen R, Kondash M, Fernandez CE, Truskey GA. A system to monitor statin-induced myopathy in individual engineered skeletal muscle myobundles. Lab on a chip. 2018 Sep;18(18):2787–96.
• Chen Z, Tang M, Huang D, Jiang W, Li M, Ji H, et al. Real-time observation of leukocyte-endothelium interactions in tissue-engineered blood vessel. Lab on a chip. 2018 Jul;18(14):2047–54.
• Chen Y-H, Chou C-H, Khodabukus A, Bursac N, Truskey G, Kraus W, et al. Effects of simulated muscle exercise on chondrocyte gene expression in a 3D-alginate bead model system. In: Osteoarthritis and Cartilage. Elsevier BV; 2018. p. S139–40.
• Marsden AL, Truskey GA. The future of biomedical engineering – Vascular bioengineering. Current Opinion in Biomedical Engineering. 2018 Mar 1;5:iii–v.
• Bishawi M, Voigt S, Bhatnagar Y, Nicoara A, Swaminathan M, Truskey G, et al. ECHOCARDIOGRAPHIC MEASUREMENT OF CARDIAC TWIST: A SYSTEMATIC REVIEW AND META-ANALYSIS. In: Journal of the American College of Cardiology. Elsevier BV; 2018. p. A1667–A1667.
• Schaefer JA, Guzman PA, Riemenschneider SB, Kamp TJ, Tranquillo RT. A cardiac patch from aligned microvessel and cardiomyocyte patches. Journal of tissue engineering and regenerative medicine. 2018 Feb;12(2):546–56.
• Boularaoui SM, Abdel-Raouf KMA, Alwahab NSA, Kondash ME, Truskey GA, Teo JCM, et al. Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle. Journal of tissue engineering and regenerative medicine. 2018 Feb;12(2):e918–36.
• Truskey GA. Human Microphysiological Systems and Organoids as in Vitro Models for Toxicological Studies. Frontiers in public health. 2018 Jan;6:185.
• Oliver CE, Davis BN, Hong J, Huffman KM, Truskey GA. Tissue-Engineered Human Skeletal Muscle Model of Rheumatoid Arthritis. In: TISSUE ENGINEERING PART A. MARY ANN LIEBERT, INC; 2017. p. S82–S82.
• Zhang X, Truskey GA. In Situ Monitoring of Engineering Muscle to Assess Myopathy. In: TISSUE ENGINEERING PART A. MARY ANN LIEBERT, INC; 2017. p. S117–S117.
• Oliver CE, Davis BN, Hong J, Huffman KM, Truskey GA. Tissue-Engineered Human Skeletal Muscle Model of Rheumatoid Arthritis. In: ARTHRITIS & RHEUMATOLOGY. WILEY; 2017.
• Atchison L, Zhang H, Cao K, Truskey GA. A Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome Using Human iPSC-derived Smooth Muscle Cells. Scientific reports. 2017 Aug;7(1):8168.
• Kondash ME, Davis BNJ, Truskey GA. Optimizing 3D Models of Engineered Skeletal Muscle. In: Engineering 3D Tissue Test Systems. CRC Press; 2017. p. 321–50.
• Davis BNJ, Santoso JW, Walker MJ, Cheng CS, Koves TR, Kraus WE, et al. Human, Tissue-Engineered, Skeletal Muscle Myobundles to Measure Oxygen Uptake and Assess Mitochondrial Toxicity. Tissue Eng Part C Methods. 2017 Apr;23(4):189–99.
• Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, et al. Corrigendum: Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle. Scientific reports. 2017 Mar;7:44517.
• Truskey GA. The future of biomedical engineering. Current Opinion in Biomedical Engineering. 2017 Mar 1;1:1–3.
• Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, et al. Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle. Scientific reports. 2017 Feb;7:42296.
• Kleinstreuer C, Hyun S, Buchanan JR, Longest PW, Archie JP, Truskey GA. Hemodynamic Parameters and Early Intimal Thickening in Branching Blood Vessels. Critical reviews in biomedical engineering. 2017 Jan;45(1–6):319–82.
• Kondash ME, Davis BNJ, Truskey GA. Optimizing 3D models of engineered skeletal muscle. In: Engineering 3D Tissue Test Systems. 2017. p. 321–50.
• Atchison LJ, Zhang H, Cao K, Truskey G. 3D Tissue Engineered Blood Vessels To Model Progeria Using iPS-derived Cell Sources. In: TISSUE ENGINEERING PART A. MARY ANN LIEBERT, INC; 2016. p. S8–S8.
• Fernandez CE, Povsic TJ, Truskey GA. Statin Responses within a Human Vascular Microphysiological System under Inflammatory Conditions. In: TISSUE ENGINEERING PART A. MARY ANN LIEBERT, INC; 2016. p. S23–S23.
• Jantzen AE, Noviani M, Mills JS, Baker KM, Lin F-H, Truskey GA, et al. Point-of-care seeding of nitinol stents with blood-derived endothelial cells. J Biomed Mater Res B Appl Biomater. 2016 Nov;104(8):1658–65.
• Cheng CS, Ran L, Bursac N, Kraus WE, Truskey GA. Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues. Tissue Eng Part A. 2016 Apr;22(7–8):573–83.
• Ji H, Atchison L, Chen Z, Chakraborty S, Jung Y, Truskey GA, et al. Transdifferentiation of human endothelial progenitors into smooth muscle cells. Biomaterials. 2016 Apr;85:180–94.
• Peters EB, Christoforou N, Leong KW, Truskey GA, West JL. Poly(ethylene glycol) Hydrogel Scaffolds Containing Cell-Adhesive and Protease-Sensitive Peptides Support Microvessel Formation by Endothelial Progenitor Cells. Cellular and molecular bioengineering. 2016 Mar;9(1):38–54.
• Fernandez CE, Yen RW, Perez SM, Bedell HW, Povsic TJ, Reichert WM, et al. Human Vascular Microphysiological System for in vitro Drug Screening. Sci Rep. 2016 Feb 18;6:21579.
• Truskey GA. Advancing cardiovascular tissue engineering. F1000Research. 2016 Jan;5:F1000FacultyRev-1045.
• Noviani M, Jamiolkowski RM, Grenet JE, Lin Q, Carlon TA, Qi L, et al. Point-of-Care Rapid-Seeding Ventricular Assist Device with Blood-Derived Endothelial Cells to Create a Living Antithrombotic Coating. ASAIO J. 2016;62(4):447–53.
• Jung Y, Ji H, Chen Z, Fai Chan H, Atchison L, Klitzman B, et al. Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels. Sci Rep. 2015 Oct 12;5:15116.
• Peters EB, Liu B, Christoforou N, West JL, Truskey GA. Umbilical Cord Blood-Derived Mononuclear Cells Exhibit Pericyte-Like Phenotype and Support Network Formation of Endothelial Progenitor Cells In Vitro. Annals of biomedical engineering. 2015 Oct;43(10):2552–68.
• Jung Y, Ji H, Chen Z, Chan H, Atchison L, Klitzman B, et al. Fabrication of Scaffold-free Tissue Engineered Blood Vessel using Nanopatterned Human Mesenchymal Stem Cell Sheet. In: TISSUE ENGINEERING PART A. MARY ANN LIEBERT, INC; 2015. p. S271–S271.
• Fernandez CE, Yen RW, Perez SL, Povsic TJ, Reichert WM, Truskey GA. Human Tissue Engineered Blood Vessels for in vitro Drug Testing. In: TISSUE ENGINEERING PART A. MARY ANN LIEBERT, INC; 2015. p. S318–S318.
• Madden L, Jackman C, Wang J, Kraus W, Truskey G, Bursac N. Novel In Vitro Exercise Model of Engineered Human Skeletal Muscle. In: TISSUE ENGINEERING PART A. MARY ANN LIEBERT, INC; 2015. p. S46–S46.
• Christoforou N, Ji H, Atchison L, Teo J, Truskey G, Leong KW. Transdifferentiation of Human Endothelial Progenitors into Functional Smooth Muscle Cells Following Induction with the Transcriptional Co-Activator MYOCD for Tissue Engineering Applications. In: TISSUE ENGINEERING PART A. MARY ANN LIEBERT, INC; 2015. p. S141–2.
• Peters EB, Liu B, Christoforou N, West JL, Truskey GA. Erratum to: Umbilical Cord Blood-Derived Mononuclear Cells Exhibit Pericyte-Like Phenotype and Support Network Formation of Endothelial Progenitor Cells In Vitro. Annals of biomedical engineering. 2015 Aug;43(8):2022.
• Truskey GA, Fernandez CE. Tissue-engineered blood vessels as promising tools for testing drug toxicity. Expert opinion on drug metabolism & toxicology. 2015 Jul;11(7):1021–4.
• Jamiolkowski RM, Kang SD, Rodriguez AK, Haseltine JM, Galinat LJ, Jantzen AE, et al. Increased yield of endothelial cells from peripheral blood for cell therapies and tissue engineering. Regenerative medicine. 2015 May;10(4):447–60.
• Cheung TM, Yan JB, Fu JJ, Huang J, Yuan F, Truskey GA. Endothelial Cell Senescence Increases Traction Forces due to Age-Associated Changes in the Glycocalyx and SIRT1. Cellular and molecular bioengineering. 2015 Mar;8(1):63–75.
• Cheung TM, Truskey GA. Environmental Factors that Influence the Response of the Endothelium to Flow. In: Aranda-Espinoza H, editor. Mechanobiology of the Endothelium. CRC Press; 2015. p. 103–31.
• Madden L, Juhas M, Kraus WE, Truskey GA, Bursac N. Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs. Elife. 2015 Jan 9;4:e04885.
• Cheung TM, Truskey GA. Environmental factors that influence the response of the endothelium to flow. In: Mechanobiology of the Endothelium. 2015. p. 103–31.
• Peters EB, Christoforou N, Moore E, West JL, Truskey GA. CD45+ Cells Present Within Mesenchymal Stem Cell Populations Affect Network Formation of Blood-Derived Endothelial Outgrowth Cells. BioResearch open access. 2015 Jan;4(1):75–88.
• Cheng CS, Davis BNJ, Madden L, Bursac N, Truskey GA. Physiology and metabolism of tissue-engineered skeletal muscle. Experimental biology and medicine (Maywood, NJ). 2014 Sep;239(9):1203–14.
• Jamiolkowski RM, Noviani M, Kang SD, Rodriguez AK, Haseltine JM, Galinat LJ, et al. Blood-Derived Endothelial Progenitor Cells Can Be Isolated With a Novel Method of Diluted Whole Blood Incubation with AMD3100-Induced Mobilization in Pigs for Personalized Antithrombotic Cell Therapy. In: MOLECULAR THERAPY. NATURE PUBLISHING GROUP; 2014. p. S280–S280.
• Cheng CS, El-Abd Y, Bui K, Hyun Y-E, Hughes RH, Kraus WE, et al. Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro. Am J Physiol Cell Physiol. 2014 Feb 15;306(4):C385–95.
• Fernandez CE, Obi-onuoha IC, Wallace CS, Satterwhite LL, Truskey GA, Reichert WM. Late-outgrowth endothelial progenitors from patients with coronary artery disease: endothelialization of confluent stromal cell layers. Acta biomaterialia. 2014 Feb;10(2):893–900.
• Fernandez CE, Achneck HE, Reichert WM, Truskey GA. Biological and engineering design considerations for vascular tissue engineered blood vessels (TEBVs). Current opinion in chemical engineering. 2014 Feb;3:83–90.
• Hong S, Jung Y, Yen R, Chan HF, Leong KW, Truskey GA, et al. Magnetoactive sponges for dynamic control of microfluidic flow patterns in microphysiological systems. Lab on a chip. 2014 Feb;14(3):514–21.
• Mills JS, Jantzen AE, Baker K, Lin F-H, Truskey GA, Achneck HE. Point-of-Care Seeded Blood-Derived Endothelial Cells Rapidly Endothelialize Nitinol Stent in a Pig Model of Personalized Cell Therapy. In: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2014.
• Cheung TM, Truskey GA. Aging endothelial cells exhibit decreased response to atheroprotective shear stress. ASME 2013 Summer Bioengineering Conference, SBC 2013. 2013 Dec 1;1 A.
• Jantzen AE, Achneck HE, Truskey GA. Surface projections of titanium substrates increase antithrombotic endothelial function in response to shear stress. Journal of biomedical materials research Part A. 2013 Nov;101(11):3181–91.
• Kang SD, Carlon TA, Jantzen AE, Lin F-H, Ley MM, Allen JD, et al. Isolation of functional human endothelial cells from small volumes of umbilical cord blood. Annals of biomedical engineering. 2013 Oct;41(10):2181–92.
• Kinev AV, Levering V, Young K, Ali-Osman F, Truskey GA, Dewhirst MW, et al. Endothelial colony forming cells (ECFCs) as a model for studying effects of low-dose ionizing radiation: growth inhibition by a single dose. Cancer Invest. 2013 Jun;31(5):359–64.
• Cheung TM, Ganatra MP, Fu JJ, Truskey GA. The Effect of Stress-Induced Senescence on Aging Human Cord Blood-Derived Endothelial Cells. Cardiovascular engineering and technology. 2013 Jun;4(2):220–30.
• Peters EB, Christoforou N, Leong KW, Truskey GA. Comparison of mixed and lamellar coculture spatial arrangements for tissue engineering capillary networks in vitro. Tissue engineering Part A. 2013 Mar;19(5–6):697–706.
• Chen Z, Lessey E, Berginski ME, Cao L, Li J, Trepat X, et al. Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration. PloS one. 2013 Jan;8(1):e52233.
• Khismatullin DB, Truskey GA. Viscoelastic Cell Adhesion Model (VECAM). In: Biophysical Journal. Elsevier BV; 2013. p. 319a-320a.
• Truskey GA, Achneck HE, Bursac N, Chan H, Cheng CS, Fernandez C, et al. Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing. Stem Cell Res Ther. 2013;4 Suppl 1(Suppl 1):S10.
• Cheung TM, Ganatra MP, Peters EB, Truskey GA. Effect of cellular senescence on the albumin permeability of blood-derived endothelial cells. American journal of physiology Heart and circulatory physiology. 2012 Dec;303(11):H1374–83.
• Shaked NT, Satterwhite LL, Telen MJ, Truskey GA, Wax A. Dynamic quantitative microscopy and nanoscopy of red blood cells in sickle cell disease. In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2012.
• Selgrade BP, Truskey GA. Computational fluid dynamics analysis to determine shear stresses and rates in a centrifugal left ventricular assist device. Artificial organs. 2012 Apr;36(4):E89–96.
• Khismatullin DB, Truskey GA. Leukocyte rolling on P-selectin: a three-dimensional numerical study of the effect of cytoplasmic viscosity. Biophysical journal. 2012 Apr;102(8):1757–66.
• Lane WO, Jantzen AE, Carlon TA, Jamiolkowski RM, Grenet JE, Ley MM, et al. Parallel-plate flow chamber and continuous flow circuit to evaluate endothelial progenitor cells under laminar flow shear stress. J Vis Exp. 2012 Jan 17;(59).
• Satterwhite LL, Shaked NT, Cyr DD, Telen MJ, Truskey GA, Wax A. Novel optical signature for sickle cell trait red blood cells. Frontiers in Optics, FIO 2012. 2012 Jan 1;
• Brown MA, Cheng CS, Truskey GA. Endothelial progenitor cells for vascular repair. In: Stem Cell Engineering: Principles and Applications. 2011. p. 297–320.
• Jantzen AE, Lane WO, Gage SM, Jamiolkowski RM, Haseltine JM, Galinat LJ, et al. Use of autologous blood-derived endothelial progenitor cells at point-of-care to protect against implant thrombosis in a large animal model. Biomaterials. 2011 Nov;32(33):8356–63.
• Jantzen AE, Lane WO, Gage SM, Haseltine JM, Galinat LJ, Jamiolkowski RM, et al. Autologous endothelial progenitor cell-seeding technology and biocompatibility testing for cardiovascular devices in large animal model. J Vis Exp. 2011 Sep 9;(55).
• Cao L, Wu A, Truskey GA. Biomechanical effects of flow and coculture on human aortic and cord blood-derived endothelial cells. Journal of biomechanics. 2011 Jul;44(11):2150–7.
• Budyansky M, Shah N, Gottfried H, Truskey P, Dekel S, Khanna AJ, et al. Minimally Invasive Iliac Crest Bone Graft Harvesting: A Design and Business Method Overview. Journal of Medical Devices. 2011 Jun 1;5(2).
• Shaked NT, Satterwhite LL, Telen MJ, Truskey GA, Wax A. Quantitative microscopy and nanoscopy of sickle red blood cells performed by wide field digital interferometry. J Biomed Opt. 2011 Mar;16(3):030506.
• Achneck HE, Jamiolkowski RM, Jantzen AE, Haseltine JM, Lane WO, Huang JK, et al. The biocompatibility of titanium cardiovascular devices seeded with autologous blood-derived endothelial progenitor cells: EPC-seeded antithrombotic Ti implants. Biomaterials. 2011 Jan;32(1):10–8.
• Jantzen AE, Lane WO, Gage SM, Haseltine JM, Galinat LJ, Jamiolkowski RM, et al. Autologous endothelial progenitor cell-seeding technology and biocompatibility testing for cardiovascular devices in large animal model. Journal of Visualized Experiments. 2011 Jan 1;(55).
• Angelos MG, Brown MA, Satterwhite LL, Levering VW, Shaked NT, Truskey GA. Dynamic adhesion of umbilical cord blood endothelial progenitor cells under laminar shear stress. Biophysical journal. 2010 Dec;99(11):3545–54.
• Rhim C, Cheng CS, Kraus WE, Truskey GA. Effect of microRNA modulation on bioartificial muscle function. Tissue Eng Part A. 2010 Dec;16(12):3589–97.
• Brown MA, Zhang L, Levering VW, Wu J-H, Satterwhite LL, Brian L, et al. Human umbilical cord blood-derived endothelial cells reendothelialize vein grafts and prevent thrombosis. Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2150–5.
• Truskey GA. Endothelial Cell Vascular Smooth Muscle Cell Co-Culture Assay For High Throughput Screening Assays For Discovery of Anti-Angiogenesis Agents and Other Therapeutic Molecules. International journal of high throughput screening. 2010 Oct;2010(1):171–81.
• Wallace CS, Truskey GA. Direct-contact co-culture between smooth muscle and endothelial cells inhibits TNF-alpha-mediated endothelial cell activation. American journal of physiology Heart and circulatory physiology. 2010 Aug;299(2):H338–46.
• Huang X, Zauscher S, Klitzman B, Truskey GA, Reichert WM, Kenan DJ, et al. Peptide interfacial biomaterials improve endothelial cell adhesion and spreading on synthetic polyglycolic acid materials. Ann Biomed Eng. 2010 Jun;38(6):1965–76.
• Pang Z, Niklason LE, Truskey GA. Porcine endothelial cells cocultured with smooth muscle cells became procoagulant in vitro. Tissue engineering Part A. 2010 Jun;16(6):1835–44.
• Brown MA, Wallace CS, Angelos M, Truskey GA. Characterization of umbilical cord blood-derived late outgrowth endothelial progenitor cells exposed to laminar shear stress. Tissue engineering Part A. 2009 Nov;15(11):3575–87.
• Stroncek JD, Grant BS, Brown MA, Povsic TJ, Truskey GA, Reichert WM. Comparison of endothelial cell phenotypic markers of late-outgrowth endothelial progenitor cells isolated from patients with coronary artery disease and healthy volunteers. Tissue Eng Part A. 2009 Nov;15(11):3473–86.
• Truskey GA, Yuan F, Katz DF. Transport Phenomena in Biological Systems. Pearson Prenticee Hall; 2009.
• Stiber JA, Zhang Z-S, Burch J, Eu JP, Zhang S, Truskey GA, et al. Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity. Mol Cell Biol. 2008 Apr;28(8):2637–47.
• Truskey GA, Irick JP. Effect of fatty acid exchange on leukocyte mechanical properties and adhesion to endothelium. In: BIORHEOLOGY. IOS PRESS; 2008. p. 32–3.
• Khismatullin DB, Truskey GA. Leukocyte rolling on P-selectin: A 3D numerical study of the effects of cell viscosity and microvillar density. BIORHEOLOGY. 2008 Jan 1;45(1–2):63–63.
• Stiber, A J, Zhang, Z-S, Burch, J, et al. Mice Lacking Homer 1Exhibit a Skeletal Myopathy 1 Characterized by Abnormal TRP Channel Activity. Mol Cell Biol. 2008;28:2637–47.
• Anamelechi CC, Clermont EE, Brown MA, Truskey GA, Reichert WM. Streptavidin binding and endothelial cell adhesion to biotinylated fibronectin. Langmuir : the ACS journal of surfaces and colloids. 2007 Dec;23(25):12583–8.
• Wallace CS, Strike SA, Truskey GA. Smooth muscle cell rigidity and extracellular matrix organization influence endothelial cell spreading and adhesion formation in coculture. American journal of physiology Heart and circulatory physiology. 2007 Sep;293(3):H1978–86.
• Brown MA, Wallace CS, Anamelechi CC, Clermont E, Reichert WM, Truskey GA. The use of mild trypsinization conditions in the detachment of endothelial cells to promote subsequent endothelialization on synthetic surfaces. Biomaterials. 2007 Sep;28(27):3928–35.
• Mathur AB, Reichert WM, Truskey GA. Flow and high affinity binding affect the elastic modulus of the nucleus, cell body and the stress fibers of endothelial cells. Annals of biomedical engineering. 2007 Jul;35(7):1120–30.
• Rhim C, Lowell DA, Reedy MC, Slentz DH, Zhang SJ, Kraus WE, et al. Morphology and ultrastructure of differentiating three-dimensional mammalian skeletal muscle in a collagen gel. Muscle Nerve. 2007 Jul;36(1):71–80.
• Zhang SJ, Truskey GA, Kraus WE. Effect of cyclic stretch on beta1D-integrin expression and activation of FAK and RhoA. Am J Physiol Cell Physiol. 2007 Jun;292(6):C2057–69.
• Wallace CS, Champion JC, Truskey GA. Adhesion and function of human endothelial cells co-cultured on smooth muscle cells. Annals of biomedical engineering. 2007 Mar;35(3):375–86.
• Khismatullin DB, Truskey GA. Three-dimensional computational modeling of leukocyte rolling and adhesion. In: 2006 ASME Joint US-European Fluids Engineering Summer Meeting, FEDSM 2006. 2006.
• Brown M, Wallace CS, Truskey GA. Vascular and Capillary Endothelium. 2006 Apr 14;
• Zhang SJY, Kraus W, Truskey G. Integrin beta 1D regulates skeletal myogenesis and mechanotransduction. In: FASEB JOURNAL. FEDERATION AMER SOC EXP BIOL; 2006. p. A391–A391.
• Ogunrinade O, Wallace CS, Truskey GA. Albumin transport across human endothelium co-cultured with vascular smooth muscle cells. Journal of Biomechanics. 2006 Jan;39:S377–8.
• Khismatullin DB, Truskey GA. Three-dimensional computational modeling of leukocyte rolling and adhesion. In: Proceedings of ASME Fluids Engineering Division Summer Meeting 2006, FEDSM2006. 2006. p. 633–8.
• McKinney VZ, Rinker KD, Truskey GA. Normal and shear stresses influence the spatial distribution of intracellular adhesion molecule-1 expression in human umbilical vein endothelial cells exposed to sudden expansion flow. Journal of biomechanics. 2006 Jan;39(5):806–17.
• Anamelechi CC, Truskey GA, Reichert WM. Mylar and Teflon-AF as cell culture substrates for studying endothelial cell adhesion. Biomaterials. 2005 Dec;26(34):6887–96.
• Lavender MD, Pang Z, Wallace CS, Niklason LE, Truskey GA. A system for the direct co-culture of endothelium on smooth muscle cells. Biomaterials. 2005 Aug;26(22):4642–53.
• Choi MG, Koh HS, Kluess D, O’Connor D, Mathur A, Truskey GA, et al. Effects of titanium particle size on osteoblast functions in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 2005 Mar;102(12):4578–83.
• Chan BP, Liu W, Klitzman B, Reichert WM, Truskey GA. In vivo performance of dual ligand augmented endothelialized expanded polytetrafluoroethylene vascular grafts. J Biomed Mater Res B Appl Biomater. 2005 Jan 15;72(1):52–63.
• Khismatullin DB, Truskey GA. Three-dimensional numerical simulation of receptor-mediated leukocyte adhesion to surfaces: Effects of cell deformability and viscoelasticity. Physics of Fluids. 2005 Jan 1;17(3).
• Chan BP, Reichert WM, Truskey GA. Synergistic effect of shear stress and streptavidin-biotin on the expression of endothelial vasodilator and cytoskeleton genes. Biotechnology and bioengineering. 2004 Dec;88(6):750–8.
• Rinker KD, Kirkpatrick AP, Ting-Beall HP, Shepherd RD, Levin JD, Irick J, et al. Linoleic acid increases monocyte deformation and adhesion to endothelium. Atherosclerosis. 2004 Dec;177(2):275–85.
• Khismatullin DB, Truskey GA. A 3D numerical study of the effect of channel height on leukocyte deformation and adhesion in parallel-plate flow chambers. Microvascular research. 2004 Nov;68(3):188–202.
• Zhang JS, Kraus WE, Truskey GA. Stretch-induced nitric oxide modulates mechanical properties of skeletal muscle cells. Am J Physiol Cell Physiol. 2004 Aug;287(2):C292–9.
• Chan BP, Reichert WM, Truskey GA. Effect of streptavidin-biotin on endothelial vasoregulation and leukocyte adhesion. Biomaterials. 2004 Aug;25(18):3951–61.
• Chan BP, Reichert WM, Truskey GA. Effect of streptavidin RGD mutant on the adhesion of endothelial cells. Biotechnology progress. 2004 Mar;20(2):566–75.
• Pourtaheri N, Truskey GA. Real-time theoretical compartmental model of blood-brain barrier drug delivery. In: Conference proceedings : . Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Annual Conference. 2004. p. 790–6.
• Mathur AB, Chan BP, Truskey GA, Reichert WM. High-affinity augmentation of endothelial cell attachment: long-term effects on focal contact and actin filament formation. Journal of biomedical materials research Part A. 2003 Sep;66(4):729–37.
• Buchanan JR, Kleinstreuer C, Hyun S, Truskey GA. Hemodynamics simulation and identification of susceptible sites of atherosclerotic lesion formation in a model abdominal aorta. Journal of biomechanics. 2003 Aug;36(8):1185–96.
• Chan BP, Reichert WM, Truskey GA. A customized DNA array reveals possible pathways for the production of streptavidin(SA)-biotin-induced nitric oxide. In: FASEB JOURNAL. FEDERATION AMER SOC EXP BIOL; 2003. p. A80–A80.
• Chan BP, Chilkoti A, Reichert WM, Truskey GA. Effect of streptavidin affinity mutants on the integrin-independent adhesion of biotinylated endothelial cells. Biomaterials. 2003 Feb;24(4):559–70.
• Mathur AB, Truskey GA, Reichert WM. Synergistic effect of high-affinity binding and flow preconditioning on endothelial cell adhesion. Journal of biomedical materials research Part A. 2003 Jan;64(1):155–63.
• Longest PW, Kleinstreuer C, Truskey GA, Buchanan JR. Relation between near-wall residence times of monocytes and early lesion growth in the rabbit aorto-celiac junction. Annals of biomedical engineering. 2003 Jan;31(1):53–64.
• Zhang J, Kraus WM, Truskey GA. The effects of the actin cytoskeleton on the transverse mechanical properties of skeletal muscle cells. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2002 Dec 1;1:400–1.
• Levin JD, Truskey GA. Increased numbers of bonds stabilize adhesion with multiple tethers between endothelium and monocytes. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2002 Dec 1;1:351–2.
• Chan BP, Reichert WM, Truskey GA. The effects of streptavidin-biotin exogenous ligands on the endothelium-derived nitric oxide synthase activity. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2002 Dec 1;1:716–7.
• Collinsworth AM, Zhang S, Kraus WE, Truskey GA. Apparent elastic modulus and hysteresis of skeletal muscle cells throughout differentiation. Am J Physiol Cell Physiol. 2002 Oct;283(4):C1219–27.
• Ogunrinade O, Kameya GT, Truskey GA. Effect of fluid shear stress on the permeability of the arterial endothelium. Annals of biomedical engineering. 2002 Apr;30(4):430–46.
• Truskey GA, Barber KM, Rinker KD. Factors influencing the nonuniform localization of monocytes in the arterial wall. Biorheology. 2002 Jan;39(3–4):325–9.
• Buchanan JR, Kleinstreuer C, Truskey GA. Influence of non-planar curvature at the rabbit aorto-celiac junction. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 2001 Dec 1;50:471–2.
• Truskey GA, Li H, Kait J, Irick J. Relationship between LDL residence time and macrophage accumulation in the rabbit aorta. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 2001 Dec 1;50:679–80.
• Buchanan JR, Kleinstreuer C, Truskey GA. The lagrangian characterization of resting flow in the rabbit abdominal aorta. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 2001 Dec 1;50:127–8.
• Mathur AB, Collinsworth AM, Reichert WM, Kraus WE, Truskey GA. Endothelial, cardiac muscle and skeletal muscle exhibit different viscous and elastic properties as determined by atomic force microscopy. J Biomech. 2001 Dec;34(12):1545–53.
• Mathur AB, Inge EW, Reichert WM, Truskey GA. Examination of the effect of stress on streptavidin-biotin/integrin-fibronectin bonds at the cell-substrate interface with the AFM-TIRFM. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2001 Apr 1;221:U347–8.
• Chan BP, Truskey GA, Reichert WM. Binding site tryptophan mutant in the high-affinity avidin-biotin complex: Effect on binding affinity and endothelial cell adhesion. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2001 Apr 1;221:U123–U123.
• Rinker KD, Prabhakar V, Truskey GA. Effect of contact time and force on monocyte adhesion to vascular endothelium. Biophysical journal. 2001 Apr;80(4):1722–32.
• Chan BP, Truskey GA, Reichert WM. Binding site tryptophan mutant in the high-affinity avidin-biotin complex: Effect on binding affinity and endothelial cell adhesion. FASEB JOURNAL. 2001 Mar 7;15(4):A451–A451.
• Slentz DH, Truskey GA, Kraus WE. Effects of chronic exposure to simulated microgravity on skeletal muscle cell proliferation and differentiation. In Vitro Cell Dev Biol Anim. 2001 Mar;37(3):148–56.
• Kleinstreuer C, Hyun S, Buchanan JR, Longest PW, Archie JP, Truskey GA. Hemodynamic parameters and early intimal thickening in branching blood vessels. Critical reviews in biomedical engineering. 2001 Jan;29(1):1–64.
• Kleinstreuer C, Buchanan Jr. J, Lei M, Truskey G. Computational Analysis of Particle-Hemodynamics and Prediction of the Onset of Arterial Diseases. In: Biomechanical Systems. CRC Press; 2000.
• Rinker KD, Ting-Beall HP, Hochmuth RM, Truskey GA. Mechanism of shear force-dependent monocyte adhesion to vascular endothelium. Annals of Biomedical Engineering. 2000 Dec 1;28(SUPPL. 1).
• Mathur A, Reichert W, Truskey G. Atomic force and total internal reflection fluorescence microscopy for the study of force transmission in endothelial cells. Annals of Biomedical Engineering. 2000 Dec 1;28(SUPPL. 1).
• Collinsworth AM, Torgan CE, Nagda SN, Rajalingam RJ, Kraus WE, Truskey GA. Orientation and length of mammalian skeletal myocytes in response to a unidirectional stretch. Cell Tissue Res. 2000 Nov;302(2):243–51.
• Torgan CE, Burge SS, Collinsworth AM, Truskey GA, Kraus WE. Differentiation of mammalian skeletal muscle cells cultured on microcarrier beads in a rotating cell culture system. Med Biol Eng Comput. 2000 Sep;38(5):583–90.
• Mathur AB, Truskey GA, Reichert WM. Atomic force and total internal reflection fluorescence microscopy for the study of force transmission in endothelial cells. Biophysical journal. 2000 Apr;78(4):1725–35.
• Mathur AB, Truskey GA, Reichert WM. Total internal reflection microscopy and atomic force microscopy (TIRFM-AFM) to study stress transduction mechanisms in endothelial cells. Critical reviews in biomedical engineering. 2000 Jan;28(1–2):197–202.
• Rinker KD, Ting-Beall HP, Hochmuth RM, Truskey GA. Mechanism of shear force-dependent monocyte adhesion to vascular endothelium. Annals of Biomedical Engineering. 2000;28(SUPPL 1):70.
• Mathur AB, Truskey GA, Reichert WM. Integration of total internal reflection and atomic force microscopy (TIRFM-AFM) to study stress transduction mechanisms in endothelial cells. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1999 Dec 1;1:3.
• Burmeister JS, McKinney VZ, Reichert WM, Truskey GA. Role of endothelial cell-substrate contact area and fibronectin-receptor affinity in cell adhesion to HEMA/EMA copolymers. Journal of biomedical materials research. 1999 Dec;47(4):577–84.
• Rinker KD, Prabhakar V, Osborn EA, Truskey GA. Effect of fluid viscosity and erythrocytes on monocyte adhesion. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1999 Dec 1;1:59.
• Buchanan JR, Hyun S, Kleinstreuer C, Truskey GA. Local monocyte deposition patterns and elevated permeabilities in the rabbit abdominal aorta. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 1999 Dec 1;42:477–8.
• Chan BP, Bhat VD, Yegnasubramanian S, Reichert WM, Truskey GA. An equilibrium model of endothelial cell adhesion via integrin-dependent and integrin-independent ligands. Biomaterials. 1999 Dec;20(23–24):2395–403.
• Zen Q, Riddle ME, Fong AM, Patel DD, Paulsen DM, Truskey G, et al. Identification and characterization of another non-integrin IgSF membrane protein receptor for laminin. FASEB JOURNAL. 1999 Apr 23;13(7):A1360–A1360.
• Buchanan JR, Kleinstreuer C, Truskey GA, Lei M. Relation between non-uniform hemodynamics and sites of altered permeability and lesion growth at the rabbit aorto-celiac junction. Atherosclerosis. 1999 Mar;143(1):27–40.
• Truskey GA, Herrmann RA, Kait J, Barber KM. Focal increases in vascular cell adhesion molecule-1 and intimal macrophages at atherosclerosis-susceptible sites in the rabbit aorta after short-term cholesterol feeding. Arteriosclerosis, thrombosis, and vascular biology. 1999 Feb;19(2):393–401.
• Zen Q, Cottman M, Truskey G, Fraser R, Telen MJ. Critical factors in basal cell adhesion molecule/lutheran-mediated adhesion to laminin. J Biol Chem. 1999 Jan 8;274(2):728–34.
• Olivier LA, Yen J, Reichert WM, Truskey GA. Short-term cell/substrate contact dynamics of subconfluent endothelial cells following exposure to laminar flow. Biotechnology progress. 1999 Jan;15(1):33–42.
• Barber KM, Pinero A, Truskey GA. Effects of recirculating flow on U-937 cell adhesion to human umbilical vein endothelial cells. American Journal of Physiology. 1998 Dec 1;275(2 PART 2).
• Mathur AB, Truskey GA, Reichert WM. Integration of total internal reflection microscopy and atomic force microscopy (TIRFM-AFM) to study mechanotransduction in endothelial cells. Critical Reviews in Biomedical Engineering. 1998 Dec 1;26(5):334–7.
• Bhat VD, Truskey GA, Reichert WM. Fibronectin and avidin–biotin as a heterogeneous ligand system for enhanced endothelial cell adhesion. Journal of Biomedical Materials Research. 1998 Sep 5;41(3):377–85.
• Bhat VD, Truskey GA, Reichert WM. Fibronectin and avidin-biotin as a heterogeneous ligand system for enhanced endothelial cell adhesion. Journal of biomedical materials research. 1998 Sep;41(3):377–85.
• Malinauskas RA, Sarraf P, Barber KM, Truskey GA. Association between secondary flow in models of the aorto-celiac junction and subendothelial macrophages in the normal rabbit. Atherosclerosis. 1998 Sep;140(1):121–34.
• Barber KM, Pinero A, Truskey GA. Effects of recirculating flow on U-937 cell adhesion to human umbilical vein endothelial cells. The American journal of physiology. 1998 Aug;275(2):H591–9.
• Barber KM, Pinero A, Truskey GA. Effects of recirculating flow on U-937 cell adhesion to human umbilical vein endothelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 1998 Aug 1;275(2):H591–9.
• Udani M, Zen Q, Cottman M, Leonard N, Jefferson S, Daymont C, et al. Erratum: (The Journal of Clinical Investigation (June 1998) 101:11 (2550-2558)). Journal of Clinical Investigation. 1998 Jul 1;102(1):269.
• Udani M, Zen Q, Cottman M, Leonard N, Jefferson S, Daymont C, et al. Basal cell adhesion molecule Lutheran protein - The receptor critical for sickle cell adhesion to laminin (vol 101, pg 2550, 1998). JOURNAL OF CLINICAL INVESTIGATION. 1998 Jul 1;102(1):271–271.
• Sharkawy AA, Klitzman B, Truskey GA, Reichert WM. Engineering the tissue which encapsulates subcutaneous implants. II. Plasma–tissue exchange properties. Journal of Biomedical Materials Research. 1998 Jun 15;40(4):586–97.
• Sharkawy AA, Klitzman B, Truskey GA, Reichert WM. Engineering the tissue which encapsulates subcutaneous implants. III. Effective tissue response times. Journal of Biomedical Materials Research. 1998 Jun 15;40(4):598–605.
• Sharkawy AA, Klitzman B, Truskey GA, Reichert WM. Engineering the tissue which encapsulates subcutaneous implants. II. Plasma-tissue exchange properties. J Biomed Mater Res. 1998 Jun 15;40(4):586–97.
• Sharkawy AA, Klitzman B, Truskey GA, Reichert WM. Engineering the tissue which encapsulates subcutaneous implants. III. Effective tissue response times. J Biomed Mater Res. 1998 Jun 15;40(4):598–605.
• Udani M, Zen Q, Cottman M, Leonard N, Jefferson S, Daymont C, et al. Basal cell adhesion molecule/lutheran protein. The receptor critical for sickle cell adhesion to laminin. J Clin Invest. 1998 Jun 1;101(11):2550–8.
• Bhat VD, Truskey GA, Reichert WM. Using avidin‐mediated binding to enhance initial endothelial cell attachment and spreading. Journal of Biomedical Materials Research. 1998 Apr;40(1):57–65.
• Bhat VD, Truskey GA, Reichert WM. Using avidin-mediated binding to enhance initial endothelial cell attachment and spreading. Journal of biomedical materials research. 1998 Apr;40(1):57–65.
• Burmeister JS, Olivier LA, Reichert WM, Truskey GA. Application of total internal reflection fluorescence microscopy to study cell adhesion to biomaterials. Biomaterials. 1998 Mar;19(4–5):307–25.
• Mathur AB, Truskey GA, Reichert WM. Integration of total internal reflection microscopy and atomic force microscopy (TIRFM-AFM) to study mechanotransduction in endothelial cells. Critical Reviews in Biomedical Engineering. 1998;26(5–6):334–7.
• Bhat VD, Klitzman B, Koger K, Truskey GA, Reichert WM. Improving endothelial cell adhesion to vascular graft surfaces: clinical need and strategies. J Biomater Sci Polym Ed. 1998;9(11):1117–35.
• Sharkawy AA, Klitzman B, Truskey GA, Reichert WM. Engineering the tissue which encapsulates subcutaneous implants. I. Diffusion properties. Journal of Biomedical Materials Research. 1997 Dec 5;37(3):401–12.
• Sharkawy AA, Klitzman B, Truskey GA, Reichert WM. Engineering the tissue which encapsulates subcutaneous implants. I. Diffusion properties. J Biomed Mater Res. 1997 Dec 5;37(3):401–12.
• Xiao Y, Truskey GA. Effect of flow recirculation upon endothelial cell height and shape. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 1997 Dec 1;35:537–8.
• Herrmann RA, Kait J, Truskey GA. Spatial distribution of VCAM-1 positive endothelium and intimal macrophages during early hypercholesterolemia. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 1997 Dec 1;35:23–4.
• Collinsworth AM, Torgan CE, Nagda SN, Spivey EC, Kraus WE, Truskey GA. The orientation of mammalian skeletal muscle followlng a unidirectional stretch. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 1997 Dec 1;35:275–6.
• Zen Q, Udani M, Cottman M, Fraser R, Truskey G, Telen MJ. B-CAM/LU protein: A single IgSF domain and copy number but not the cytoplasmic region are critical for laminin binding. BLOOD. 1997 Nov 15;90(10):2685–2685.
• Bhat VD, Truskey GA, Reichert WM. Avidin-biotin as an extrinsic, high affinity receptor-ligand system to enhance initial cell attachment and spreading. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 1997 Apr 13;213:357-COLL.
• Sharkawy A, Klitzman B, Truskey G, Reichert W. Diffusion properties of tissue which encapsulates subcutaneous implants. Vol. 213, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. AMER CHEMICAL SOC; 1997. p. 342-PMSE.
• Sharkawy A, Klitzman B, Truskey G, Reichert W. Diffusion properties of tissue which encapsulates subcutaneous implants. Vol. 76, Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering. 1997. p. 568–9.
• Sharkawy AA, Klitzman B, Truskey GA, Reichert WM. Diffusion properties of capsular tissue. Vol. 2, Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium. 1996. p. 132.
• du Laney TV, Truskey GA, Klitzman B. Fibronectin enhances cell spreading and retention on ePTFE under shear in vitro. Vol. 1, Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium. 1996. p. 560.
• Xiao Y, Truskey GA. Effect of receptor-ligand affinity on the strength of endothelial cell adhesion. Biophysical journal. 1996 Nov;71(5):2869–84.
• Kanai AJ, Malinski T, Birder LA, Truskey GA, Finkel MS. Constitutive nitric oxide release from vascular endothelial cells, cardiac myocytes and neurons. CIRCULATION. 1996 Oct 15;94(8):2026–2026.
• Lei M, Kleinstreuer C, Truskey GA. A focal stress gradient-dependent mass transfer mechanism for atherogenesis in branching arteries. Medical engineering & physics. 1996 Jun;18(4):326–32.
• Burmeister JS, Vrany JD, Reichert WM, Truskey GA. Effect of fibronectin amount and conformation on the strength of endothelial cell adhesion to HEMA/EMA copolymers. Journal of biomedical materials research. 1996 Jan;30(1):13–22.
• Lei M, Kleinstreuer C, Truskey GA, Archie JP. THE ZERO-TENSION HYPOTHESIS FOR THE MECHANISM OF ATHEROGENESIS AND THE WALL SHEAR STRESS GRADIENT (WSSG) PREDICTOR EQUATION. In: ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE). 1996. p. 211–2.
• Kanai AJ, Strauss HC, Truskey GA, Crews AL, Grunfeld S, Malinski T. Shear stress induces ATP-independent transient nitric oxide release from vascular endothelial cells, measured directly with a porphyrinic microsensor. Circulation research. 1995 Aug;77(2):284–93.
• Lei M, Kleinstreuer C, Truskey GA. Numerical investigation and prediction of atherogenic sites in branching arteries. Journal of biomechanical engineering. 1995 Aug;117(3):350–7.
• Malinauskas RA, Herrmann RA, Truskey GA. The distribution of intimal white blood cells in the normal rabbit aorta. Atherosclerosis. 1995 Jun;115(2):147–63.
• Truskey GA, Barber KM, Robey TC, Olivier LA, Combs MP. Characterization of a sudden expansion flow chamber to study the response of endothelium to flow recirculation. Journal of biomechanical engineering. 1995 May;117(2):203–10.
• Olivier LA, Reichert WM, Truskey GA. Dynamic response of endothelial cells to flow as measured by total internal reflectance fluorescence microscopy. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 1995 Jan 1;29:565–6.
• Kanai AJ, Strauss HC, Malinski T, Truskey GA. Characterization of shear stress dependent release of nitric oxide from endothelial cells in vitro. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 1995 Jan 1;29:573–4.
• Truskey GA, Herrmann RA, Malinauskas RA. Low density lipoprotein transport in the arterial wall of normal and hypercholesterolemic rabbits. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 1995 Jan 1;29:129–30.
• Herrmann RA, Malinauskas RA, Truskey GA. Characterization of sites with elevated LDL permeability at intercostal, celiac, and iliac branches of the normal rabbit aorta. Arteriosclerosis and thrombosis : a journal of vascular biology. 1994 Feb;14(2):313–23.
• Burmeister JS, Truskey GA, Yarbrough JL, Reichert WM. Imaging of cell/substrate contacts on polymers by total internal reflection fluorescence microscopy. Biotechnology progress. 1994 Jan;10(1):26–31.
• Burmeister JS, Truskey GA, Reichert WM. Quantitative analysis of variable-angle total internal reflection fluorescence microscopy (VA-TIRFM) of cell/substrate contacts. Journal of microscopy. 1994 Jan;173(Pt 1):39–51.
• Banovac F, Saavedra SS, Truskey GA. Local conformational changes of vitronectin upon adsorption on glass and silane surfaces. Journal of Colloid And Interface Science. 1994 Jan 1;165(1):31–40.
• Olivier LA, Truskey GA. A numerical analysis of forces exerted by laminar flow on spreading cells in a parallel plate flow chamber assay. Biotechnology and bioengineering. 1993 Oct;42(8):963–73.
• Iuliano DJ, Saavedra SS, Truskey GA. Effect of the conformation and orientation of adsorbed fibronectin on endothelial cell spreading and the strength of adhesion. Journal of biomedical materials research. 1993 Aug;27(8):1103–13.
• Truskey GA, Proulx TL. Relationship between 3T3 cell spreading and the strength of adhesion on glass and silane surfaces. Biomaterials. 1993 Jan;14(4):243–54.
• du Laney TV, Cherry RS, Coppinger JA, Truskey GA. Altered distribution of mitochondria and actin fibers in 3T3 cells cultured on microcarriers. Biotechnology progress. 1992 Nov;8(6):572–5.
• Truskey GA, Burmeister JS, Grapa E, Reichert WM. Total internal reflection fluorescence microscopy (TIRFM). II. Topographical mapping of relative cell/substratum separation distances. Journal of cell science. 1992 Oct;103 ( Pt 2):491–9.
• Truskey GA, Roberts WL, Herrmann RA, Malinauskas RA. Measurement of endothelial permeability to 125I-low density lipoproteins in rabbit arteries by use of en face preparations. Circulation research. 1992 Oct;71(4):883–97.
• BURMEISTER JS, REICHERT WM, TRUSKEY GA. MEASUREMENT OF CELL CONTACT AREA ON FIBRONECTIN-COATED SURFACES BY VARIABLE ANGLE TOTAL INTERNAL-REFLECTION FLUORESCENCE MICROSCOPY (TIRFM). ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 1992 Aug 23;204:17-COLL.
• TRUSKEY GA. Total internal reflection fluorescence microscopy (TIRFM). II. Topographical mapping of relative cell/substratum separation distances. J Cell Sci. 1992;103:491–9.
• Garrison MD, Iuliano DJ, Saavedra SS, Truskey GA, Reichert WM. Postadsorption changes in the emission maximum of acrylodan-labeled bovine serum albumin using total internal reflection fluorescence. Journal of Colloid And Interface Science. 1992 Jan 1;148(2):415–24.
• Burmeister J, Truskey GA, Reichert WM. Variable angle total internal reflection fluorescence (TIRF) microscopy of fluorescently labelled lipid films and cells at the glass-liquid interface. Annals of Biomedical Engineering. 1991 Dec 1;19(5):614.
• Olivier LA, Truskey GA. Numerical simulation of forces on a spreading cell exposed to flow. Annals of Biomedical Engineering. 1991 Dec 1;19(5):607.
• Herrmann RA, Malinauskas RA, Truskey GA. Regional variations in endothelial permeability to ¹²⁵I-low density lipoproteins in rabbit arteries. Annals of Biomedical Engineering. 1991 Dec 1;19(5):606.
• Iuliano DJ, Proulx TL, Saavedra SS, Truskey GA. Role of adhesion proteins and cytoskeleton in the short-term response of fibroblasts and endothelial cells to steady laminar flow. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 1991 Dec 1;21:23–5.
• HERRMANN RA, ROBERTS WL, MALINAUSKAS RA, TRUSKEY GA. FOCAL REGIONS OF INCREASED ARTERIAL PERMEABILITY TO LOW-DENSITY-LIPOPROTEIN (LDL) INVIVO MEASURED BY AUTORADIOGRAPHY. FASEB JOURNAL. 1991 Mar 15;5(5):A1251–A1251.
• TRUSKEY GA, IULIANO DJ, SAAVEDRA SS. THE EFFECT OF THE CONFORMATION OF ADSORBED FIBRONECTIN (FN) ON ENDOTHELIAL-CELL ADHESION. FASEB JOURNAL. 1991 Mar 11;5(4):A372–A372.
• Truskey GA, Proulx TL. Quantitation of cell area on glass and fibronectin-coated surfaces by digital image analysis. Biotechnology progress. 1990 Nov;6(6):513–9.
• Truskey GA, Pirone JS. The effect of fluid shear stress upon cell adhesion to fibronectin-treated surfaces. Journal of biomedical materials research. 1990 Oct;24(10):1333–53.
• Truskey GA, Nicolakis DP, DiMasi D, Haberman A, Swartz RW. Kinetic studies and unstructured models of lymphocyte metabolism in fed-batch culture. Biotechnology and bioengineering. 1990 Oct;36(8):797–807.
• TRUSKEY GA, REICHERT WM, GRAPA E. A METHOD TO MEASURE CELL-SEPARATION DISTANCES USING TOTAL INTERNAL-REFLECTION FLUORESCENCE. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 1990 Aug 26;200:155-BIOT.
• Reichert WM, Truskey GA. Total internal reflection fluorescence (TIRF) microscopy. I. Modelling cell contact region fluorescence. Journal of cell science. 1990 Jun;96 ( Pt 2):219–30.
• REICHERT WM, TRUSKEY GA, WINAKUR E. TOTAL INTERNAL-REFLECTION FLUORESCENCE VIDEO MICROSCOPY OF CELL-SURFACE CONTACTS. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. AMER CHEMICAL SOC; 1989. p. 177-ANYL.
• NICOLAKIS DP, TRUSKEY GA, HABERMAN A, SWARTZ RW. METABOLIC STUDIES OF HYBRIDOMAS IN FED-BATCH BIOREACTOR. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. AMER CHEMICAL SOC; 1988. p. 1-MBTD.
• Truskey GA, Gabler R, DiLeo A, Manter T. The effect of membrane filtration upon protein conformation. Journal of parenteral science and technology : a publication of the Parenteral Drug Association. 1987 Nov;41(6):180–93.
• Davies PF, Truskey GA, Warren HB, O’Connor SE, Eisenhaure BH. Metabolic cooperation between vascular endothelial cells and smooth muscle cells in co-culture: changes in low density lipoprotein metabolism. The Journal of cell biology. 1985 Sep;101(3):871–9.
• Truskey GA, Davies PF. Effects of ammonium ion derived from bovine endothelial cells upon low density lipoprotein degradation in cultured vascular smooth muscle cells. Cell biology international reports. 1985 Apr;9(4):323–30.
• TRUSKEY GA, COLTON CK, DAVIES PF. Kinetic Analysis of Receptor‐Mediated Endocytosis and Lysosomal Degradation in Cultured Cells. Annals of the New York Academy of Sciences. 1984 Jan 1;435(1):349–51.
• Truskey GA, Colton CK, Smith KA. Quantitative Analysis of Protein Transport in the Arterial Wall. In: Structure and Function of the Circulation. Springer US; 1981. p. 287–355.
• TRUSKEY G, DEUTSCH C, FORSTER RE. DETERMINATION OF ENERGY OF ACTIVATION FOR ACETIC-ACID AND ACETATE ION-TRANSPORT IN THE HUMAN ERYTHROCYTE. In: FEDERATION PROCEEDINGS. FEDERATION AMER SOC EXP BIOL; 1979. p. 1127–1127.

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