Charles Gersbach

Image of Charles Gersbach

Rooney Family Associate Professor of Biomedical Engineering

Appointments and Affiliations
  • Rooney Family Associate Professor of Biomedical Engineering
  • Associate Professor of Biomedical Engineering
  • Associate Professor of Orthopaedic Surgery
  • Affiliate of the Duke Initiative for Science & Society
  • Member of Duke Cancer Institute
Contact Information:
Education:

  • Ph.D. Georgia Institute of Technology, 2006
  • B.S. Georgia Institute of Technology, 2001

Research Interests:

Dr. Gersbach's research interests are in gene therapy, biomolecular and cellular engineering, regenerative medicine, and synthetic biology.

Specialties:

Drug Delivery
Genomics
Tissue Repair, Tissue Engineering
Polymer and Protein Engineering
Biological Materials

Awards, Honors, and Distinctions:

    Courses Taught:
    • BME 260L: Modeling Cellular and Molecular Systems
    • BME 394: Projects in Biomedical Engineering (GE)
    • BME 493: Projects in Biomedical Engineering (GE)
    • BME 494: Projects in Biomedical Engineering (GE)
    • BME 562: Biology by Design (GE, MC)
    • BME 711S: Biological Engineering Seminar Series (CBIMMS and CBTE)
    • BME 712S: Biological Engineering Seminar Series (CBIMMS and CBTE)
    • BME 791: Graduate Independent Study
    • EGR 391: Projects in Engineering
    • EGR 393: Research Projects in Engineering
    • GENOME 293: Research Independent Study Genome Sciences
    • GENOME 294: Research Independent Study Genome Sciences
    • ME 717S: Biological Engineering Seminar Series (CBIMMS and CBTE)
    • ME 718S: Biological Engineering Seminar Series (CBIMMS and CBTE)

    Representative Publications: (More Publications)
      • Maeder, ML; Gersbach, CA, Genome-editing Technologies for Gene and Cell Therapy, Molecular Therapy, vol 24 no. 3 (2016), pp. 430-446 [10.1038/mt.2016.10] [abs].
      • Landau, DJ; Brooks, ED; Perez-Pinera, P; Amarasekara, H; Mefferd, A; Li, S; Bird, A; Gersbach, CA; Koeberl, DD, In Vivo Zinc Finger Nuclease-Mediated Targeted Integration of a Glucose-6-Phosphatase Transgene Promotes Survival in Mice with Glycogen Storage Disease Type IA., Molecular Therapy (2016) [10.1038/mt.2016.35] [abs].
      • Thakore, PI; Black, JB; Hilton, IB; Gersbach, CA, Editing the epigenome: technologies for programmable transcription and epigenetic modulation, Nature Methods, vol 13 no. 2 (2016), pp. 127-137 [10.1038/nmeth.3733] [abs].
      • Nelson, CE; Hakim, CH; Ousterout, DG; Thakore, PI; Moreb, EA; Rivera, RMC; Madhavan, S; Pan, X; Ran, FA; Yan, WX; Asokan, A; Zhang, F; Duan, D; Gersbach, CA, In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy, Science, vol 351 no. 6271 (2016), pp. 403-407 [10.1126/science.aad5143] [abs].
      • Thakore, PI; Gersbach, CA, Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors., Methods in molecular biology (Clifton, N.J.), vol 1338 (2016), pp. 71-88 [10.1007/978-1-4939-2932-0_7] [abs].