Charles Gersbach

Image of Charles Gersbach

Associate Professor of Biomedical Engineering

Appointments and Affiliations
  • Associate Professor of Biomedical Engineering
  • Associate Professor of Orthopaedic Surgery
  • Affiliate of the Duke Initiative for Science & Society
  • Member of Duke Cancer Institute
Contact Information:
Education:

  • Ph.D. Georgia Institute of Technology, 2006
  • B.S. Georgia Institute of Technology, 2001

Research Interests:

Dr. Gersbach's research interests are in gene therapy, biomolecular and cellular engineering, regenerative medicine, and synthetic biology.

Specialties:

Drug Delivery
Genomics
Tissue Repair, Tissue Engineering
Polymer and Protein Engineering
Biological Materials

Awards, Honors, and Distinctions:

    Courses Taught:
    • BME 260L: Modeling Cellular and Molecular Systems
    • BME 394: Projects in Biomedical Engineering (GE)
    • BME 493: Projects in Biomedical Engineering (GE)
    • BME 494: Projects in Biomedical Engineering (GE)
    • BME 562: Biology by Design (GE, MC)
    • BME 711S: Biological Engineering Seminar Series (CBIMMS and CBTE)
    • BME 712S: Biological Engineering Seminar Series (CBIMMS and CBTE)
    • BME 791: Graduate Independent Study
    • EGR 391: Projects in Engineering
    • EGR 393: Research Projects in Engineering
    • GENOME 293: Research Independent Study Genome Sciences
    • GENOME 294: Research Independent Study Genome Sciences
    • ME 717S: Biological Engineering Seminar Series (CBIMMS and CBTE)
    • ME 718S: Biological Engineering Seminar Series (CBIMMS and CBTE)

    Representative Publications: (More Publications)
      • Ousterout, DG; Gersbach, CA, The Development of TALE Nucleases for Biotechnology., Methods in molecular biology (Clifton, N.J.), vol 1338 (2016), pp. 27-42 [10.1007/978-1-4939-2932-0_3] [abs].
      • Thakore, PI; Gersbach, CA, Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors., Methods in molecular biology (Clifton, N.J.), vol 1338 (2016), pp. 71-88 [10.1007/978-1-4939-2932-0_7] [abs].
      • Hilton, IB; Gersbach, CA, Enabling functional genomics with genome engineering., Genome research, vol 25 no. 10 (2015), pp. 1442-1455 [10.1101/gr.190124.115] [abs].
      • Polstein, LR; Perez-Pinera, P; Kocak, DD; Vockley, CM; Bledsoe, P; Song, L; Safi, A; Crawford, GE; Reddy, TE; Gersbach, CA, Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators., Genome research, vol 25 no. 8 (2015), pp. 1158-1169 [10.1101/gr.179044.114] [abs].
      • Gibson, TM; Gersbach, CA, Single-molecule analysis of myocyte differentiation reveals bimodal lineage commitment., Integrative Biology, vol 7 no. 6 (2015), pp. 663-671 [10.1039/c5ib00057b] [abs].