Charles A Gersbach
Rooney Family Associate Professor of Biomedical Engineering
Appointments and Affiliations
- Rooney Family Associate Professor of Biomedical Engineering
- Associate Professor of Biomedical Engineering
- Associate Professor of Orthopaedic Surgery
- Affiliate of the Duke Initiative for Science & Society
- Member of the Duke Cancer Institute
- Office Phone: (919) 613-2147
- Email Address: email@example.com
- Ph.D. Georgia Institute of Technology, 2006
- B.S. Georgia Institute of Technology, 2001
Dr. Gersbach's research interests are in gene therapy, biomolecular and cellular engineering, regenerative medicine, and synthetic biology.
Tissue Repair, Tissue Engineering
Polymer and Protein Engineering
- BME 260L: Modeling Cellular and Molecular Systems
- BME 394: Projects in Biomedical Engineering (GE)
- BME 493: Projects in Biomedical Engineering (GE)
- BME 494: Projects in Biomedical Engineering (GE)
- BME 562: Biology by Design (GE, MC)
- BME 711S: Biological Engineering Seminar Series (CBIMMS and CBTE)
- BME 712S: Biological Engineering Seminar Series (CBIMMS and CBTE)
- BME 791: Graduate Independent Study
- EGR 391: Projects in Engineering
- EGR 393: Research Projects in Engineering
- GENOME 293: Research Independent Study Genome Sciences
- GENOME 294: Research Independent Study Genome Sciences
- ME 717S: Biological Engineering Seminar Series (CBIMMS and CBTE)
- ME 718S: Biological Engineering Seminar Series (CBIMMS and CBTE)
In the News
- Duke Awards Distinguished Professorships, Inducts New Bass Society Members (May 5, 2016)
- Gene editing treats disease in mice (Jan 4, 2016 | BBC News )
- Gene editing offers hope for treating Duchenne muscular dystrophy, studies find (Jan 4, 2016 | The New York Times )
- CRISPR Treats Genetic Disorder in Adult Mammal (Dec 31, 2015)
- Pratt Research Brings Precise Control to Gene Expression (Oct 27, 2015)
- Studying the Harm and Healing Power of Steroids (May 26, 2015)
- Engineers gain control of gene activity; new therapies may be ahead (Apr 6, 2015)
- Bacterial Defense Mechanism Targets Duchenne Muscular Dystrophy (Feb 19, 2015)
- Bacterial Defense Mechanism Targets Duchenne Muscular Dystrophy (Feb 18, 2015)
- Lighting Up the Duke 'D' With Genes (Feb 10, 2015)
- Nelson, CE; Gersbach, CA, Engineering Delivery Vehicles for Genome Editing, Annual Review of Chemical and Biomolecular Engineering, vol 7 no. 1 (2016), pp. 637-662 [10.1146/annurev-chembioeng-080615-034711] [abs].
- Landau, DJ; Brooks, ED; Perez-Pinera, P; Amarasekara, H; Mefferd, A; Li, S; Bird, A; Gersbach, CA; Koeberl, DD, In Vivo Zinc Finger Nuclease-mediated Targeted Integration of a Glucose-6-phosphatase Transgene Promotes Survival in Mice With Glycogen Storage Disease Type IA., Molecular Therapy, vol 24 no. 4 (2016), pp. 697-706 [abs].
- Nelson, CE; Gersbach, CA, Cas9 loosens its grip on off-target sites, Nature Biotechnology, vol 34 no. 3 (2016), pp. 298-299 [10.1038/nbt.3501] [abs].
- Josephs, EA; Kocak, DD; Fitzgibbon, CJ; McMenemy, J; Gersbach, CA; Marszalek, PE, Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage., Nucleic Acids Research, vol 44 no. 5 (2016) [abs].
- Thakore, PI; Black, JB; Hilton, IB; Gersbach, CA, Editing the epigenome: technologies for programmable transcription and epigenetic modulation, Nature Methods, vol 13 no. 2 (2016), pp. 127-137 [10.1038/nmeth.3733] [abs].