Biomaterials
Duke BME is home to a diverse and longstanding research community focusing on the area of biomaterials, the discipline of studying and designing non-living materials and devices that interface with physiological systems.
Ongoing interests include the molecular design of soft materials, nanomaterials, immune-active materials, scaffolds for tissue engineering, and basic investigations into the complex mechanisms by which materials engage biology.
Research in the broad field of Biomaterials has led to the development of an incredible range of implantable biomedical devices over the past several decades, and it continues to be central to the introduction of new medical therapies ranging from engineered tissues to delivery vehicles for genes and drugs, to immune therapies.
The biomaterials research community at Duke is supported and enhanced by numerous centers and programs, including the Research Triangle NSF Materials Research Science and Engineering Center (RT-MRSEC) and the Center for Biomolecular and Tissue Engineering (CBTE).
Primary Faculty
Ashutosh Chilkoti
Alan L. Kaganov Professor of Biomedical Engineering
Research Interests: Focused on biomolecular materials and biointerface science and emphasizes the development of applications that span the range from bioseparations, biosensors, biomaterials, and targeted drug delivery.
Joel Collier
Associate Professor in the Department of Biomedical Engineering
Research Interests: The design of biomaterials for a range of biomedical applications, with a focus on understanding and controlling adaptive immune responses. Most materials investigated are created from molecular assemblies- proteins, peptides or bioconjugates that self-organize into useful...
Charles Gersbach
Rooney Family Associate Professor of Biomedical Engineering
Research Interests: Gene therapy, genomics and epigenomics, biomolecular and cellular engineering, regenerative medicine, and synthetic biology.
Brenton D. Hoffman
Assistant Professor of Biomedical Engineering
Research Interests: Focused on understanding, on a molecular level, how mechanical and chemical cues from the environment are detected, integrated, and manipulated by cells to dictate physiological and patho-physiological responses important in vascular biology.
David F. Katz
Nello L. Teer, Jr. Professor of Biomedical Engineering, in the Edmund T. Pratt, Jr. School of Engineering
Research Interests: Methods for prophylaxis against STD's, emphasizing topical microbicides and contraception; biofluid mechanics; rheology and transport phenomena; biophysical aspects of mammalian sperm motility, sperm transport, and fertilization; and biomechanical functioning of the vitreous of...
Michael Rubinstein
Professor of Biomedical Engineering, and Mechanical Engineering and Materials Science
Research Interests: Polymer theory and computer simulations
Tatiana Segura
Professor of Biomedical Engineering
Research Interests: The design of biomaterials to promote endogenous repair and reducing inflammation through the design of the geometry of the material, and delivering genes, proteins and drugs.
Shyni Varghese
Professor of Biomedical Engineering, Mechanical Engineering & Materials Science and Orthopaedics
Research Interests: Musculoskeletal tissue repair, disease biophysics and organ-on-a-chip technology
Tuan Vo-Dinh
R. Eugene and Susie E. Goodson Professor of Biomedical Engineering
Research Interests: Biophotonics, laser-excited luminescence spectroscopy, room temperature phosphorimetry, synchronous luminescence spectroscopy, surface-enhanced Raman spectroscopy, field environmental instrumentation, fiberoptics sensors, nanosensors, biosensors and biochips for the protection...
Lingchong You
Professor of Biomedical Engineering
Research Interests: Computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.
Secondary Faculty
Gaurav Arya
Associate Professor of Mechanical Engineering and Materials Science
Research Interests: Molecular modeling, molecular simulations, statistical mechanics, coarse-graining, machine learning, polymer and colloidal physics, polymer-nanoparticle composites, chromatin biophysics, DNA nanotechnology, viral DNA packaging, single-molecule force spectroscopy, nanoscale...
Research Faculty
Cameron R. Bass
Associate Research Professor of Biomedical Engineering
Research Interests: Dr. Bass's research interests include the biomechanics of blast, blunt and ballistic trauma and pediatric trauma. His research focuses on injury risk from microscale to macroscale for the head, neck, thorax and extremities.
Nassir Mokarram-Dorri
Consulting Associate in the Biomedical Engineering
Research Interests: Immunomodulation for nervous system repair; medical devices for brain tumor therapy; biomaterials for tissue engineering.