Tony Jun Huang

Research Interests

Acoustofluidics, microfluidics, lab-on-a-chip, biomedical micro-electro-mechanical systems (BioMEMS), optofluidics, plasmofluidics.

Bio

Tony Jun Huang received his Ph.D. degree in Mechanical and Aerospace Engineering from the University of California, Los Angeles (UCLA) in 2005. His research interests are in the fields of acoustofluidics, optofluidics, and micro/nano systems for biomedical diagnostics and therapeutics. He has authored/co-authored over 290 peer-reviewed journal publications in these fields. His journal articles have been cited more than 29,000 times, as documented at Google Scholar (h-index: 91).He also has 30 issued or pending US/international patents. 

Prof. Huang was elected a fellow (member) of the National Academy of Inventors (USA) and the European Academy of Sciences and Arts. He was also a fellow of the following six professional societies: the American Association for the Advancement of Science (AAAS), the American Institute for Medical and Biological Engineering (AIMBE), the American Society of Mechanical Engineers (ASME), the Institute of Electrical and Electronics Engineers (IEEE), the Institute of Physics (UK), and the Royal Society of Chemistry (UK).

Huang's research has gained international recognition through numerous prestigious awards and honors including a 2010 National Institutes of Health (NIH) Director's New Innovator Award, a 2011 JALA Top Ten Breakthroughs of the Year Award, a 2012 Outstanding Young Manufacturing Engineer Award from the Society for Manufacturing Engineering, a 2013 Faculty Scholar Medal from The Pennsylvania State University, a 2013 American Asthma Foundation (AAF) Scholar Award, the 2014 IEEE Sensors Council Technical Achievement Award from the Institute of Electrical and Electronics Engineers (IEEE), the 2017 Analytical Chemistry Young Innovator Award from the American Chemical Society (ACS), the 2019 Van C. Mow Medal from the American Society of Mechanical Engineers (ASME), and the 2019 Technical Achievement Award from the IEEE Engineering in Medicine and Biology Society (EMBS).

Education

• Ph.D. University of California, Los Angeles, 2005

Positions

• William Bevan Distinguished Professor of Mechanical Engineering and Materials Science
• Professor in the Thomas Lord Department of Mechanical Engineering and Materials Science
• Professor of Biomedical Engineering

Awards, Honors, and Distinctions

• Fellow (NAI). National Academy of Inventors. 2020

Courses Taught

• ME 591: Research Independent Study in Mechanical Engineering or Material Science
• ME 535: Biomedical Microsystems
• EGR 393: Research Projects in Engineering
• BME 791: Graduate Independent Study
• BME 494: Projects in Biomedical Engineering (GE)
• BME 493: Projects in Biomedical Engineering (GE)

Publications

• Tian Z, Yang S, Huang P-H, Wang Z, Zhang P, Gu Y, et al. Wave number-spiral acoustic tweezers for dynamic and reconfigurable manipulation of particles and cells. Science advances. 2019 May;5(5):eaau6062.
• Ozcelik A, Rufo J, Guo F, Gu Y, Li P, Lata J, et al. Acoustic tweezers for the life sciences. Nature methods. 2018 Dec;15(12):1021–8.
• Chen C, Zhang SP, Mao Z, Nama N, Gu Y, Huang P-H, et al. Three-dimensional numerical simulation and experimental investigation of boundary-driven streaming in surface acoustic wave microfluidics. Lab on a chip. 2018 Dec;18(23):3645–54.
• Wu M, Chen K, Yang S, Wang Z, Huang P-H, Mai J, et al. High-throughput cell focusing and separation via acoustofluidic tweezers. Lab on a chip. 2018 Sep;18(19):3003–10.
• Zhang SP, Lata J, Chen C, Mai J, Guo F, Tian Z, et al. Digital acoustofluidics enables contactless and programmable liquid handling. Nature communications. 2018 Jul;9(1):2928.
• Huang P-H, Chan CY, Li P, Wang Y, Nama N, Bachman H, et al. A sharp-edge-based acoustofluidic chemical signal generator. Lab on a chip. 2018 May;18(10):1411–21.
• Austin RG, Huang TJ, Wu M, Armstrong AJ, Zhang T. Clinical utility of non-EpCAM based circulating tumor cell assays. Adv Drug Deliv Rev. 2018 Feb 1;125:132–42.
• Bachman H, Huang P-H, Zhao S, Yang S, Zhang P, Fu H, et al. Acoustofluidic devices controlled by cell phones. Lab on a chip. 2018 Jan;18(3):433–41.
• Wu M, Ouyang Y, Wang Z, Zhang R, Huang P-H, Chen C, et al. Isolation of exosomes from whole blood by integrating acoustics and microfluidics. Proceedings of the National Academy of Sciences of the United States of America. 2017 Oct;114(40):10584–9.
• Ayan B, Ozcelik A, Bachman H, Tang S-Y, Xie Y, Wu M, et al. Acoustofluidic coating of particles and cells. Lab on a chip. 2016 Nov;16(22):4366–72.
• Ozcelik A, Nama N, Huang P-H, Kaynak M, McReynolds MR, Hanna-Rose W, et al. Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures. Small (Weinheim an der Bergstrasse, Germany). 2016 Oct;12(37):5120–5.
• Chen Y, Wu M, Ren L, Liu J, Whitley PH, Wang L, et al. High-throughput acoustic separation of platelets from whole blood. Lab on a chip. 2016 Sep;16(18):3466–72.
• Ahmed D, Ozcelik A, Bojanala N, Nama N, Upadhyay A, Chen Y, et al. Rotational manipulation of single cells and organisms using acoustic waves. Nature Communications. 2016 Mar 23;7(1).
• Guo F, Mao Z, Chen Y, Xie Z, Lata JP, Li P, et al. Three-dimensional manipulation of single cells using surface acoustic waves. Proceedings of the National Academy of Sciences. 2016 Feb 9;113(6):1522–7.
• Li P, Mao Z, Peng Z, Zhou L, Chen Y, Huang P-H, et al. Acoustic separation of circulating tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 2015 Apr;112(16):4970–5.
• Guo F, Li P, French JB, Mao Z, Zhao H, Li S, et al. Controlling cell–cell interactions using surface acoustic waves. Proceedings of the National Academy of Sciences. 2015 Jan 6;112(1):43–8.
• Huang P-H, Nama N, Mao Z, Li P, Rufo J, Chen Y, et al. A reliable and programmable acoustofluidic pump powered by oscillating sharp-edge structures. Lab on a chip. 2014 Nov;14(22):4319–23.
• Huang P-H, Xie Y, Ahmed D, Rufo J, Nama N, Chen Y, et al. An acoustofluidic micromixer based on oscillating sidewall sharp-edges. Lab on a chip. 2013 Oct;13(19):3847–52.
• Ding X, Li P, Lin S-CS, Stratton ZS, Nama N, Guo F, et al. Surface acoustic wave microfluidics. Lab on a Chip. 2013;13(18):3626–3626.
• Ding X, Lin S-CS, Kiraly B, Yue H, Li S, Chiang I-K, et al. On-chip manipulation of single microparticles, cells, and organisms using surface acoustic waves. Proceedings of the National Academy of Sciences. 2012 Jul 10;109(28):11105–9.
• Ahmed D, Mao X, Shi J, Juluri BK, Huang TJ. A millisecond micromixer via single-bubble-based acoustic streaming. Lab on a Chip. 2009;9(18):2738–2738.
• Shi J, Ahmed D, Mao X, Lin S-CS, Lawit A, Huang TJ. Acoustic tweezers: patterning cells and microparticles using standing surface acoustic waves (SSAW). Lab on a Chip. 2009;9(20):2890–2890.
• Shi J, Huang H, Stratton Z, Huang Y, Huang TJ. Continuous particle separation in a microfluidic channel via standing surface acoustic waves (SSAW). Lab on a Chip. 2009;9(23):3354–3354.
• Shi J, Mao X, Ahmed D, Colletti A, Huang TJ. Focusing microparticles in a microfluidic channel with standing surface acoustic waves (SSAW). Lab Chip. 2008;8(2):221–3.

In The News

• Which Duke Scholars Made the Most Cited List? (Nov 16, 2023 | Duke Research Blog)
• Biologic Used by Athletes Could Also Ease Nerve Pain from Chemo, Diabetes (May 22, 2023 | Duke Health News)
• Sound-Induced Electric Fields Control the Tiniest Particles (Jun 23, 2021 | )
• Sound Waves Spin Droplets to Concentrate, Separate Nanoparticles (Jan 5, 2021 | Pratt School of Engineering)
• Huang Elected to the National Academy of Inventors (Dec 8, 2020 | )
• Sound Waves Replace Human Hands in Petri Dish Experiments (Sep 11, 2020 | Pratt School of Engineering)
• Seven From Duke Named Fellows of American Association for the Advancement of Science (Nov 26, 2019 | )