Kathryn Radabaugh Nightingale

Research Themes

Biomechanics & Mechanobiology, Biomedical Imaging & Biophotonics

Research Interests

Ultrasonic and elasticity imaging; image-guided therapies; biomechanical tissue modeling; ultrasonic bioeffects.

Bio

The goals of our laboratory are to investigate and improve ultrasonic imaging methods for clinically-relevant problems. We do this through theoretical, experimental, and simulation methods. The main focus of our recent work is the development of novel, acoustic radiation force impulse (ARFI)-based elasticity imaging methods to generate images of the mechanical properties of tissue, involving interdisciplinary research in ultrasonics and tissue biomechanics. We have access to the engineering interfaces of several commercial ultrasound systems which allows us to design, rapidly prototype, and experimentally demonstrate custom sequences to explore novel beamforming and imaging concepts. We employ FEM modeling methods to simulate the behavior of tissues during mechanical excitation, and we have integrated these tools with ultrasonic imaging modeling tools to simulate the ARFI imaging process. We maintain strong collaborations with the Duke University Medical Center where we work to translate our technologies to clinical practice. The ARFI imaging technologies we have developed have served as the basis for commercial imaging technologies that are now being used in clinics throughout the world.  We are also studying the risks and benefits of increasing acoustic output energy for specific clinical imaging scenarios, with the goal of improving ultrasonic image quality in the difficult-to-image patient.

Education

• B.S. Duke University, 1989
• Ph.D. Duke University, 1997

Positions

• Theo Pilkington Distinguished Professor of Biomedical Engineering
• Professor in the Department of Biomedical Engineering
• Member of the Duke Cancer Institute
• Bass Fellow

Awards, Honors, and Distinctions

• Joseph H. Holmes Basic Science Pioneer Award. American Institute of Ultrasound in Medicine. 2022
• Fellow (NAI). National Academy of Inventors. 2019
• Lois and John L. Imhoff Distinguished Teaching Award. Pratt School of Engineering. 2018
• Fellow. American Institute for Medical and Biological Engineering. 2016
• Capers and Marion McDonald Teaching and Research Award. Pratt School of Engineering. 2015
• Klein Family Distinguished Teaching Award. Pratt School of Engineering. 2007

Courses Taught

• BME 845: Elasticity Imaging
• BME 791: Graduate Independent Study
• BME 789: Internship in Biomedical Engineering
• BME 729S: Teaching Seminar for Repeat Teaching Assistants
• BME 728S: Teaching Seminar for New Teaching Assistants
• BME 702S: BME Graduate Seminars
• BME 701S: BME Graduate Seminars
• BME 542: Principles of Ultrasound Imaging (GE, IM)
• BME 494: Projects in Biomedical Engineering (GE)
• BME 493: Projects in Biomedical Engineering (GE)
• BME 493-1: Projects in Biomedical Engineering (GE)
• BME 354L: Introduction to Medical Instrumentation

Publications

• Chan DY, Morris DC, Moavenzadeh SR, Lye TH, Polascik TJ, Palmeri ML, et al. Multiparametric Ultrasound Imaging of Prostate Cancer Using Deep Neural Networks. Ultrasound Med Biol. 2024 Nov;50(11):1716–23.
• Caenen A, Bézy S, Pernot M, Nightingale KR, Vos HJ, Voigt J-U, et al. Ultrasound Shear Wave Elastography in Cardiology. JACC Cardiovascular imaging. 2024 Mar;17(3):314–29.
• Paley CT, Knight AE, Jin FQ, Moavenzadeh SR, Rouze NC, Pietrosimone LS, et al. Rotational 3D shear wave elasticity imaging: Effect of knee flexion on 3D shear wave propagation in in vivo vastus lateralis. J Mech Behav Biomed Mater. 2024 Feb;150:106302.
• Chan DY, Morris DC, Polascik TJ, Palmeri ML, Nightingale KR. Combined ARFI and Shear Wave Imaging of Prostate Cancer: Optimizing Beam Sequences and Parameter Reconstruction Approaches. Ultrason Imaging. 2023 Jul;45(4):175–86.
• Zhang B, Bottenus N, Jin FQ, Nightingale KR. Quantifying the Impact of Imaging Through Body Walls on Shear Wave Elasticity Measurements. Ultrasound in medicine & biology. 2023 Mar;49(3):734–49.
• Paley CT, Knight AE, Jin FQ, Moavenzadeh SR, Pietrosimone LS, Hobson-Webb LD, et al. Repeatability of Rotational 3-D Shear Wave Elasticity Imaging Measurements in Skeletal Muscle. Ultrasound Med Biol. 2023 Mar;49(3):750–60.
• Jin FQ, Rouze NC, Paley CT, Nightingale KR, Palmeri ML. Physics-informed neural networks for modeling acoustic radiation force-induced shear wave propagation and the reconstruction of material parameters from observations. In: IEEE International Ultrasonics Symposium, IUS. 2023.
• Knight AE, Jin FQ, Paley CT, Rouze NC, Moavenzadeh SR, Pietrosimone LS, et al. Parametric Analysis of SV Mode Shear Waves in Transversely Isotropic Materials Using Ultrasonic Rotational 3-D SWEI. IEEE Trans Ultrason Ferroelectr Freq Control. 2022 Nov;69(11):3145–54.
• McCune EP, Le DQ, Lindholm P, Nightingale KR, Dayton PA, Papadopoulou V. Perspective on ultrasound bioeffects and possible implications for continuous post-dive monitoring safety. Diving and hyperbaric medicine. 2022 Jun;52(2):136–48.
• Rouze NC, Caenen A, Nightingale KR. Phase and group velocities for shear wave propagation in an incompressible, hyperelastic material with uniaxial stretch. Physics in medicine and biology. 2022 Apr;67(9).
• Geoghegan R, Ter Haar G, Nightingale K, Marks L, Natarajan S. Methods of monitoring thermal ablation of soft tissue tumors - A comprehensive review. Medical physics. 2022 Feb;49(2):769–91.
• Jin FQ, Rouze NC, Knight AE, Nightingale KR, Palmeri ML. Modeling Shear Wave Propagation in an Incompressible, Transversely Isotropic Material Using Physics-Informed Neural Networks. In: IEEE International Ultrasonics Symposium, IUS. 2022.
• Chan DY, Moavenzadeh SR, Polascik TJ, Palmeri ML, Nightingale KR. Screening and Image-Guided Targeted Biopsy of Prostate Cancer Using 3D Acoustic Radiation Force Impulse (ARFI) Imaging. In: IEEE International Ultrasonics Symposium, IUS. 2022.
• Jin FQ, Knight AE, Paley CT, Pietrosimone LS, Hobson-Webb LD, Nightingale KR, et al. An Open-Source Radon-Transform Shear Wave Speed Estimator with Masking Functionality to Isolate Different Shear-Wave Modes. In: IEEE International Ultrasonics Symposium, IUS. 2022.
• Knight AE, Trutna CA, Rouze NC, Hobson-Webb LD, Caenen A, Jin FQ, et al. Full Characterization of in vivo Muscle as an Elastic, Incompressible, Transversely Isotropic Material Using Ultrasonic Rotational 3D Shear Wave Elasticity Imaging. IEEE Trans Med Imaging. 2022 Jan;41(1):133–44.
• Caenen A, Pernot M, Nightingale KR, Voigt J-U, Vos HJ, Segers P, et al. Assessing cardiac stiffness using ultrasound shear wave elastography. Physics in medicine and biology. 2022 Jan;67(2).
• Paley CT, Knight AE, Jin FQ, Moavenzadeh S, Rouze NC, Pietrosimone LS, et al. On the correlation between knee flexion and 3D shear wave speed and amplitude in in vivo vastus lateralis. In: IEEE International Ultrasonics Symposium, IUS. 2022.
• Rouze NC, Knight AE, Nightingale KR. Uniqueness of shear wave modeling in an incompressible, transversely isotropic (ITI) material. Physics in medicine and biology. 2021 Oct;66(21).
• Zhang B, Pinton GF, Nightingale KR. On the Relationship between Spatial Coherence and In Situ Pressure for Abdominal Imaging. Ultrasound in medicine & biology. 2021 Aug;47(8):2310–20.
• Jin FQ, Knight AE, Cardones AR, Nightingale KR, Palmeri ML. Semi-automated weak annotation for deep neural network skin thickness measurement. Ultrason Imaging. 2021 Jul;43(4):167–74.
• Morris DC, Chan DY, Palmeri ML, Polascik TJ, Foo W-C, Nightingale KR. Prostate Cancer Detection Using 3-D Shear Wave Elasticity Imaging. Ultrasound Med Biol. 2021 Jul;47(7):1670–80.
• Chan DY, Morris DC, Polascik TJ, Palmeri ML, Nightingale KR. Deep Convolutional Neural Networks for Displacement Estimation in ARFI Imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2021 Jul;68(7):2472–81.
• Zhang B, Pinton GF, Deng Y, Nightingale KR. Quantifying the Effect of Abdominal Body Wall on In Situ Peak Rarefaction Pressure During Diagnostic Ultrasound Imaging. Ultrasound in medicine & biology. 2021 Jun;47(6):1548–58.
• Palmeri ML, Milkowski A, Barr R, Carson P, Couade M, Chen J, et al. Radiological Society of North America/Quantitative Imaging Biomarker Alliance Shear Wave Speed Bias Quantification in Elastic and Viscoelastic Phantoms. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 2021 Mar;40(3):569–81.
• Jin FQ, Trutna CA, Knight AE, Hobson-Webb LD, Nightingale KR, Palmeri ML. Quantification of Skeletal Muscle Fiber Orientation in 3D Ultrasound B-Modes. In: IEEE International Ultrasonics Symposium, IUS. 2021.
• Chan DY, Morris DC, Lye T, Polascik TJ, Palmeri ML, Mamou J, et al. Deep neural network for multiparametric ultrasound imaging of prostate cancer. In: IEEE International Ultrasonics Symposium, IUS. 2021.
• Knight AE, Trutna CA, Jin FQ, Rouze NC, Pietrosimone LS, Hobson-Webb LD, et al. Factors Affecting in vivo SH and SV Mode Wave Propagation in vastus lateralis Muscle at Varying Knee Flexion Angles Using Ultrasonic Rotational 3D SWEI. In: IEEE International Ultrasonics Symposium, IUS. 2021.
• Trutna CA, Knight AE, Jin FQ, Rouze NC, Pietrosimone LS, Toth AP, et al. Group Shear Wave Speed Viscoelastic Analysis using 3D Rotational Volumetric Shear Wave Imaging in Relaxed and Contracted in vivo Muscle. In: IEEE International Ultrasonics Symposium, IUS. 2021.
• Morris DC, Chan DY, Lye TH, Chen H, Palmeri ML, Polascik TJ, et al. Multiparametric Ultrasound for Targeting Prostate Cancer: Combining ARFI, SWEI, QUS and B-Mode. Ultrasound Med Biol. 2020 Dec;46(12):3426–39.
• Knight AE, Trutna CA, Rouze NC, Hobson-Webb LD, Palmeri ML, Caenen A, et al. Demonstration of Complex Shear Wave Patterns in Skeletal Muscle in vivo Using 3D SWEI. In: IEEE International Ultrasonics Symposium, IUS. 2020.
• Trutna CA, Knight AE, Rouze NC, Hobson-Webb LD, Palmeri ML, Nightingale KR. Viscoelastic Characterization in Muscle using Group Speed Analysis and Volumetric Shear Wave Elasticity Imaging. In: IEEE International Ultrasonics Symposium, IUS. 2020.
• Chan DY, Morris DC, Lye T, Polascik TJ, Palmeri ML, Mamou J, et al. Evaluating Image Quality Improvement in Multiparametric Ultrasound Imaging of Prostate Cancer by Combining ARFI, SWEI, B-mode, and QUS. In: IEEE International Ultrasonics Symposium, IUS. 2020.
• Caenen A, Knight AE, Rouze NC, Bottenus NB, Segers P, Nightingale KR. Analysis of multiple shear wave modes in a nonlinear soft solid: Experiments and finite element simulations with a tilted acoustic radiation force. Journal of the mechanical behavior of biomedical materials. 2020 Jul;107:103754.
• Knight AE, Lipman SL, Ketsiri T, Hobson-Webb LD, Nightingale KR. On the Challenges Associated with Obtaining Reproducible Measurements Using SWEI in the Median Nerve. Ultrasound Med Biol. 2020 May;46(5):1092–104.
• Trutna CA, Rouze NC, Palmeri ML, Nightingale KR. Measurement of Viscoelastic Material Model Parameters Using Fractional Derivative Group Shear Wave Speeds in Simulation and Phantom Data. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2020 Feb;67(2):286–95.
• Rouze NC, Palmeri ML, Nightingale KR. Tractable calculation of the Green's tensor for shear wave propagation in an incompressible, transversely isotropic material. Physics in medicine and biology. 2020 Jan;65(1):015014.
• Trutna CA, Lipman SL, Palmeri ML, Nightingale KR. Large Field-Of-View Shear Wave Elasticity Imaging with Combined On- and Off-Axis Stiffness Estimation for High Frame Rate Hepatic HCC Screening. In: IEEE International Ultrasonics Symposium, IUS. 2019. p. 1368–71.
• Trutna CA, Rouze NC, Palmeri ML, Nightingale KR. Robust Model-Based Viscoelastic Characterization of QIBA Phantoms through Fractional Derivative Group Shear Wave Speeds. In: IEEE International Ultrasonics Symposium, IUS. 2019. p. 1391–4.
• Zhang B, Nightingale KR. Experimental Comparison of Diagnostic Imaging Pressure Fields through the Abdominal Wall with Water. In: IEEE International Ultrasonics Symposium, IUS. 2019. p. 2230–2.
• Jin FQ, Postiglione M, Knight AE, Cardones AR, Nightingale KR, Palmeri ML. Comparison of Deep Learning and Classical Image Processing for Skin Segmentation. In: IEEE International Ultrasonics Symposium, IUS. 2019. p. 1152–5.
• Morris DC, Chan DY, Chen H, Palmeri ML, Polascik TJ, Foo WC, et al. Multiparametric Ultrasound for the Targeting of Prostate Cancer using ARFI, SWEI, B-mode, and QUS. In: IEEE International Ultrasonics Symposium, IUS. 2019. p. 880–3.
• Chan DY, Rouze NC, Palmeri ML, Nightingale KR. Bayesian Shear Wave Speed Reconstruction with an On-Axis ARFI Prior. In: IEEE International Ultrasonics Symposium, IUS. 2019. p. 213–6.
• Chan DY, Morris DC, Palmeri ML, Nightingale KR. A Fully Convolutional Neural Network for Rapid Displacement Estimation in ARFI Imaging. In: IEEE International Ultrasonics Symposium, IUS. 2019. p. 111–4.
• Knight AE, Pely AB, Jin FQ, Cardones AR, Palmeri ML, Nightingale KR. Analysis of Factors Affecting Shear Wave Speed in in vivo Skin. In: IEEE International Ultrasonics Symposium, IUS. 2019. p. 970–3.
• Caenen A, Knight AE, Rouze NC, Bottenus NB, Segers P, Nightingale KR. Measuring elastic nonlinearity in a soft solid using a tilted acoustic radiation force for shear wave excitation. In: IEEE International Ultrasonics Symposium, IUS. 2019. p. 221–3.
• Rouze NC, Caenen A, Nightingale KR. Wave Speeds and Green's Tensors for Shear Wave Propagation in Incompressible, Hyperelastic Materials with Uniaxial Stretch. In: IEEE International Ultrasonics Symposium, IUS. 2019. p. 427–30.
• Zhang B, Long W, Pinton GF, Nightingale KR. On the Use of Spatial Coherence for in Situ Peak Rarefaction Pressure Estimation. In: IEEE International Ultrasonics Symposium, IUS. 2018.
• Rouze NC, Deng Y, Trutna CA, Palmeri ML, Nightingale KR. Characterization of Viscoelastic Materials Using Group Shear Wave Speeds. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2018 May;65(5):780–94.
• Lipman SL, Rouze NC, Palmeri ML, Nightingale KR. Impact of Acoustic Radiation Force Excitation Geometry on Shear Wave Dispersion and Attenuation Estimates. Ultrasound in medicine & biology. 2018 Apr;44(4):897–908.
• Deng Y, Palmeri ML, Rouze NC, Haystead CM, Nightingale KR. Evaluating the Benefit of Elevated Acoustic Output in Harmonic Motion Estimation in Ultrasonic Shear Wave Elasticity Imaging. Ultrasound Med Biol. 2018 Feb;44(2):303–10.
• Cody Morris D, Chan DY, Palmeri ML, Glass TJ, McCormick MM, Jack Tay K, et al. Correlation Between 3D ARFI and Quantitative Imaging Metrics from SWEI and Multi-Parametric MRI in Vivo in Normal and Cancerous Prostate Tissue. In: IEEE International Ultrasonics Symposium, IUS. 2018.
• Hollender P, Knight A, Caenen A, Shashikumar N, Lee I, Palmeri M, et al. Anisotropic Constructive Shearwave Interference Measurement of Transversely Anisotropic Materials. In: IEEE International Ultrasonics Symposium, IUS. 2018.
• Lipman SL, Palmeri ML, Nightingale KR. Large Field-of-View Shear Wave Imaging for Hepatocellular Carcinoma Screening. In: IEEE International Ultrasonics Symposium, IUS. 2018.
• Chan DY, Lipman SL, Palmeri ML, Morris DC, Polascik TJ, Rouze NC, et al. Prostate Shear Wave Elastography: Multiresolution Reconstruction Dependence on Push Beam Spacing. In: IEEE International Ultrasonics Symposium, IUS. 2018.
• Knight A, Hollender P, Nightingale K, Palmeri M. Constructive shearwave imaging: Feasibility and improvements in SNR. In: IEEE International Ultrasonics Symposium, IUS. 2017.
• Morris DC, Rouze N, Palmeri M, Nightingale K. Group-shearwave based viscoelastic parameter estimation: Analysis of sources of bias. In: IEEE International Ultrasonics Symposium, IUS. 2017.
• Zhang B, Pinton G, Tripathi B, Deng Y, Nightingale K. Nonlinear ultrasound propagation in homogeneous and heterogeneous media: Factors affecting the in situ Mechanical Index (MI). In: IEEE International Ultrasonics Symposium, IUS. 2017.
• Rouze NC, Trutna CA, Deng Y, Palmeri ML, Nightingale KR. Notice of Removal: Comparison of methods for measuring the frequency dependent phase velocity and attenuation in viscoelastic materials. In: IEEE International Ultrasonics Symposium, IUS. 2017.
• Zhang B, Pinton G, Deng Y, Tripathi B, Nightingale K. Nonlinear Ultrasound Propagation in Homogeneous and Heterogeneous Media: Factors Affecting the in situ Mechanical Index (MI). In: IEEE International Ultrasonics Symposium, IUS. 2017.
• Knight A, Hollender P, Shashikumar N, Nightingale K, Palmeri M. Constructive shearwave interference (CSI): Concept and feasibility. In: IEEE International Ultrasonics Symposium, IUS. 2017.
• Morris DC, Rouze NC, Palmeri ML, Nightingale KR. Group shear wave based viscoelastic parameter estimation in SWEI: Analysis of sources of bias. In: IEEE International Ultrasonics Symposium, IUS. 2017.
• Deng Y, Palmeri M, Rouze N, Haystead C, Nightingale K. Notice of Removal: Investigating the impact of elevated acoustic output in B-mode harmonic imaging and harmonic motion tracking. In: IEEE International Ultrasonics Symposium, IUS. 2017.
• Rouze NC, Trutna CA, Deng Y, Palmeri ML, Nightingale KR. Comparison of SWEI methods for measuring the frequency dependent phase velocity and attenuation in viscoelastic materials. In: IEEE International Ultrasonics Symposium, IUS. 2017.
• Deng Y, Palmeri ML, Rouze NC, Trahey GE, Haystead CM, Nightingale KR. Quantifying Image Quality Improvement Using Elevated Acoustic Output in B-Mode Harmonic Imaging. Ultrasound Med Biol. 2017 Oct;43(10):2416–25.
• Rouze NC, Deng Y, Palmeri ML, Nightingale KR. Accounting for the Spatial Observation Window in the 2-D Fourier Transform Analysis of Shear Wave Attenuation. Ultrasound in medicine & biology. 2017 Oct;43(10):2500–6.
• Deng Y, Rouze NC, Palmeri ML, Nightingale KR. Ultrasonic Shear Wave Elasticity Imaging Sequencing and Data Processing Using a Verasonics Research Scanner. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2017 Jan;64(1):164–76.
• Palmeri M, Glass T, Gupta R, McCormick M, Brown A, Polascik T, et al. Comparison between 3D ARFI imaging and mpMRI in detecting clinically-significant prostate cancer lesions. In: IEEE International Ultrasonics Symposium, IUS. 2016.
• Pely A, Nightingale KR, Palmeri ML. Dispersion analysis in skin using FEM: Characterizing the effects of the lower boundary material on the propagation of shear waves. In: IEEE International Ultrasonics Symposium, IUS. 2016.
• Lipman SL, Rouze NC, Palmeri ML, Nightingale KR. On the feasibility of estimating ultrasonic shear wave attenuation using amplitude-based methods. In: IEEE International Ultrasonics Symposium, IUS. 2016.
• Rouze NC, Deng Y, Palmeri ML, Nightingale KR. Robust characterization of viscoelastic materials from measurements of group shear wave speeds. In: IEEE International Ultrasonics Symposium, IUS. 2016.
• Lipman SL, Rouze NC, Palmeri ML, Nightingale KR. Evaluating the Improvement in Shear Wave Speed Image Quality Using Multidimensional Directional Filters in the Presence of Reflection Artifacts. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2016 Aug;63(8):1049–63.
• Palmeri ML, Glass TJ, Miller ZA, Rosenzweig SJ, Buck A, Polascik TJ, et al. Identifying Clinically Significant Prostate Cancers using 3-D In Vivo Acoustic Radiation Force Impulse Imaging with Whole-Mount Histology Validation. Ultrasound Med Biol. 2016 Jun;42(6):1251–62.
• Deng Y, Rouze NC, Palmeri ML, Nightingale KR. On System-Dependent Sources of Uncertainty and Bias in Ultrasonic Quantitative Shear-Wave Imaging. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2016 Mar;63(3):381–93.
• Rouze NC, Palmeri ML, Nightingale KR. Measurement of the frequency dependent phase velocity and attenuation from the Fourier description of shear wave propagation: Addressing geometric spreading arising from spatially asymmetric Gaussian excitations. In: 2015 IEEE International Ultrasonics Symposium, IUS 2015. 2015.
• Deng Y, Palmeri ML, Rouze NC, Haysteady CM, Nightingale KR. Quantifying the benefit of elevated acoustic output in harmonic imaging. In: 2015 IEEE International Ultrasonics Symposium, IUS 2015. 2015.
• Lee SY, Cardones AR, Nightingale K, Palmeri M. Characterizing sclerotic skin stiffness with Acoustic Radiation Force Impulse (ARFI) and Shear Wave Elasticity Imaging (SWEI). In: 2015 IEEE International Ultrasonics Symposium, IUS 2015. 2015.
• Palmeri M, Nightingale K, Fielding S, Rouze N, Deng Y, Lynch T, et al. RSNA QIBA ultrasound shear wave speed Phase II phantom study in viscoelastic media. In: 2015 IEEE International Ultrasonics Symposium, IUS 2015. 2015.
• Deng Y, Rouze NC, Palmeri ML, Nightingale KR. System dependent sources of error in time-of-flight shear wave speed measurements. In: 2015 IEEE International Ultrasonics Symposium, IUS 2015. 2015.
• Lee SY, Cardones AR, Doherty J, Nightingale K, Palmeri M. Preliminary Results on the Feasibility of Using ARFI/SWEI to Assess Cutaneous Sclerotic Diseases. Ultrasound Med Biol. 2015 Nov;41(11):2806–19.
• Rouze NC, Palmeri ML, Nightingale KR. An analytic, Fourier domain description of shear wave propagation in a viscoelastic medium using asymmetric Gaussian sources. The Journal of the Acoustical Society of America. 2015 Aug;138(2):1012–22.
• Deng Y, Palmeri ML, Rouze NC, Rosenzweig SJ, Abdelmalek MF, Nightingale KR. Analyzing the Impact of Increasing Mechanical Index and Energy Deposition on Shear Wave Speed Reconstruction in Human Liver. Ultrasound in medicine & biology. 2015 Jul;41(7):1948–57.
• Nightingale KR, Church CC, Harris G, Wear KA, Bailey MR, Carson PL, et al. Conditionally Increased Acoustic Pressures in Nonfetal Diagnostic Ultrasound Examinations Without Contrast Agents: A Preliminary Assessment. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 2015 Jul;34(7):1–41.
• Shiina T, Nightingale KR, Palmeri ML, Hall TJ, Bamber JC, Barr RG, et al. WFUMB guidelines and recommendations for clinical use of ultrasound elastography: Part 1: basic principles and terminology. Ultrasound in medicine & biology. 2015 May;41(5):1126–47.
• Ferraioli G, Filice C, Castera L, Choi BI, Sporea I, Wilson SR, et al. WFUMB guidelines and recommendations for clinical use of ultrasound elastography: Part 3: liver. Ultrasound in medicine & biology. 2015 May;41(5):1161–79.
• Barr RG, Nakashima K, Amy D, Cosgrove D, Farrokh A, Schafer F, et al. WFUMB guidelines and recommendations for clinical use of ultrasound elastography: Part 2: breast. Ultrasound in medicine & biology. 2015 May;41(5):1148–60.
• Hollender PJ, Rosenzweig SJ, Nightingale KR, Trahey GE. Single- and multiple-track-location shear wave and acoustic radiation force impulse imaging: matched comparison of contrast, contrast-to-noise ratio and resolution. Ultrasound in medicine & biology. 2015 Apr;41(4):1043–57.
• Rosenzweig S, Palmeri M, Nightingale K. Analysis of rapid multi-focal-zone ARFI imaging. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2015 Feb;62(2):280–9.
• Church CC, Labuda C, Nightingale K. A theoretical study of inertial cavitation from acoustic radiation force impulse imaging and implications for the mechanical index. Ultrasound in medicine & biology. 2015 Feb;41(2):472–85.
• Nightingale KR, Rouze NC, Rosenzweig SJ, Wang MH, Abdelmalek MF, Guy CD, et al. Derivation and analysis of viscoelastic properties in human liver: impact of frequency on fibrosis and steatosis staging. IEEE Trans Ultrason Ferroelectr Freq Control. 2015 Jan;62(1):165–75.
• Doherty JR, Palmeri ML, Trahey GE, Nightingale KR. Acoustic Radiation Force-Based Elasticity Imaging. In: Ultrasound Imaging and Therapy. 2015. p. 229–59.
• Rosenzweig S, Miller Z, Polascik T, Nightingale K. Prostate elastography. In: Prostate Ultrasound: Current Practice and Future Directions. 2015. p. 163–72.
• Palmeri ML, Miller ZA, Glass TJ, Garcia-Reyes K, Gupta RT, Rosenzweig SJ, et al. B-mode and acoustic radiation force impulse (ARFI) imaging of prostate zonal anatomy: comparison with 3T T2-weighted MR imaging. Ultrason Imaging. 2015 Jan;37(1):22–41.
• Deng Y, Palmeri ML, Rouze NC, Rosenzweig SJ, Abdelmalek MF, Nightingale KR. Analyzing the impact of increasing Mechanical Index (MI) and energy deposition on shear wave speed (SWS) reconstruction in human liver. In: IEEE International Ultrasonics Symposium, IUS. 2014. p. 719–22.
• Miller ZA, Palmeri ML, Rosenzweig SJ, Glass TJ, Nightingale KR, Polascik TJ, et al. 3D in vivo ARFI imaging: Prostate cancer sensitivity. In: IEEE International Ultrasonics Symposium, IUS. 2014. p. 209–12.
• Lipman SL, Rouze NC, Palmeri ML, Nightingale KR. Improving the accuracy of shear wave speed reconstructions using 4D directional filters in the presence of reflection artifacts. In: IEEE International Ultrasonics Symposium, IUS. 2014. p. 2312–5.
• Hollender P, Rosenzweig S, Nightingale K, Trahey G. Micro-elasticity (μ-E): CNR and resolution of acoustic radiation force impulse imaging and single- and multiple track location shear wave elasticity imaging for visualizing small targets. In: IEEE International Ultrasonics Symposium, IUS. 2014. p. 703–6.
• Rouze NC, Palmeri ML, Nightingale KR. Estimation of model parameters characterizing dispersion in ARFI induced shear waves in in vivo human liver. In: IEEE International Ultrasonics Symposium, IUS. 2014. p. 983–6.
• Palmeri ML, Deng Y, Rouze NC, Nightingale KR. Dependence of shear wave spectral content on acoustic radiation force excitation duration and spatial beamwidth. In: IEEE International Ultrasonics Symposium, IUS. 2014. p. 1105–8.
• Nightingale KR, Rouze NC, Wang MH, Rosenzweig SJ, Palmeri ML. 3D elasticity imaging with acoustic radiation force. In: IEEE International Ultrasonics Symposium, IUS. 2013. p. 531–6.
• Hall TJ, Milkowski A, Garra B, Carson P, Palmeri M, Nightingale K, et al. RSNA/QIBA: Shear wave speed as a biomarker for liver fibrosis staging. In: IEEE International Ultrasonics Symposium, IUS. 2013. p. 397–400.
• Rosenzweig S, Rouze N, Byram B, Palmeri M, Polascik T, Nightingale K. Bayesian shear wave speed estimation for in vivo 3D imaging of the prostate. In: IEEE International Ultrasonics Symposium, IUS. 2013. p. 1260–3.
• Rouze NC, Wang MH, Palmeri ML, Nightingale KR. Finite element modeling of impulsive excitation and shear wave propagation in an incompressible, transversely isotropic medium. Journal of biomechanics. 2013 Nov;46(16):2761–8.
• Wang M, Byram B, Palmeri M, Rouze N, Nightingale K. Imaging transverse isotropic properties of muscle by monitoring acoustic radiation force induced shear waves using a 2-D matrix ultrasound array. IEEE transactions on medical imaging. 2013 Sep;32(9):1671–84.
• Wang M, Byram B, Palmeri M, Rouze N, Nightingale K. On the precision of time-of-flight shear wave speed estimation in homogeneous soft solids: initial results using a matrix array transducer. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2013 Apr;60(4):758–70.
• Doherty JR, Trahey GE, Nightingale KR, Palmeri ML. Acoustic radiation force elasticity imaging in diagnostic ultrasound. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2013 Apr;60(4):685–701.
• Rosenzweig S, Zhai L, Nightingale KR. Prostate elastrography. In: Imaging and Focal Therapy of Early Prostate Cancer. 2013. p. 165–72.
• Wang MH, Byram BC, Palmeri ML, Rouze NC, Nightingale KR. 3D shear wave imaging of anisotropic mechanical properties of muscle using a 2D matrix array transducer. In: IEEE International Ultrasonics Symposium, IUS. 2012. p. 5–8.
• Rotemberg V, Byram B, Wang M, Palmeri ML, Nightingale KR. Characterizing expansion and stiffening of the canine liver with increasing hepatic pressure. In: IEEE International Ultrasonics Symposium, IUS. 2012. p. 101–4.
• Rosenzweig S, Palmeri M, Rouze N, Lipman S, Kulbacki E, Madden J, et al. Comparison of concurrently acquired in vivo 3D ARFI and SWEI images of the prostate. In: IEEE International Ultrasonics Symposium, IUS. 2012. p. 97–100.
• Church CC, Labuda C, Nightingale K. Should the mechanical index be revised for ARFI imaging? IEEE International Ultrasonics Symposium : [proceedings] IEEE International Ultrasonics Symposium. 2012 Oct;2012:17–20.
• Rouze NC, Wang MH, Palmeri ML, Nightingale KR. Parameters affecting the resolution and accuracy of 2-D quantitative shear wave images. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2012 Aug;59(8):1729–40.
• Howles GP, Qi Y, Rosenzweig SJ, Nightingale KR, Johnson GA. Functional neuroimaging using ultrasonic blood-brain barrier disruption and manganese-enhanced MRI. J Vis Exp. 2012 Jul 12;(65):e4055.
• Palmeri ML, Abdelmalek MF, Nightingale KR. Reply to: The use of acoustic radiation force-based shear stiffness in non-alcoholic fatty liver disease. Journal of Hepatology. 2012 Apr 1;56(4):996.
• Rotemberg V, Palmeri M, Nightingale R, Rouze N, Nightingale K. The impact of hepatic pressurization on liver shear wave speed estimates in constrained versus unconstrained conditions. Physics in medicine and biology. 2012 Jan;57(2):329–41.
• Nightingale K, Wang M, Rosenzweig S, Rotemberg V, Rouze N, Palmeri M. TH‐C‐217BCD‐06: Acoustic Radiation Force Based Imaging: An Overview. In: Medical Physics. 2012. p. 4004.
• Zhai L, Polascik TJ, Foo W-C, Rosenzweig S, Palmeri ML, Madden J, et al. Acoustic radiation force impulse imaging of human prostates: initial in vivo demonstration. Ultrasound Med Biol. 2012 Jan;38(1):50–61.
• Hsu CML, Polascik TJ, Davenport MS, Kauffman C, Gupta RT, Kulbacki E, et al. Methodology to register prostate B-mode and ARFI images to MR and histology. In: IEEE International Ultrasonics Symposium, IUS. 2011. p. 1866–9.
• Rotemberg V, Palmeri ML, Rouze NC, Nightingale R, Nightingale KR. Comparison between Acoustic Radiation Force Impulse (ARFI)-based hepatic stiffness quantification in deformed and undeformed pressurized canine livers. IEEE International Ultrasonics Symposium, IUS. 2011 Dec 1;2090–3.
• Wang MH, Byram BC, Palmeri ML, Rouze NC, Nightingale KR. Improving shear wave speed estimation precision in homogeneous media by tracking shear wave propagation in 3D using a real-time volumetric imaging transducer. IEEE International Ultrasonics Symposium, IUS. 2011 Dec 1;1262–5.
• Nightingale KR, Rouze NC, Wang MH, Zhai L, Palmeri ML. Comparison of qualitative and quantitative acoustic radiation force based elasticity imaging methods. In: Proceedings - International Symposium on Biomedical Imaging. 2011. p. 1606–9.
• Nightingale K. Acoustic Radiation Force Impulse (ARFI) Imaging: a Review. Current medical imaging reviews. 2011 Nov;7(4):328–39.
• Bing KF, Rouze NC, Palmeri ML, Rotemberg VM, Nightingale KR. Combined ultrasonic thermal ablation with interleaved ARFI image monitoring using a single diagnostic curvilinear array: a feasibility study. Ultrasonic imaging. 2011 Oct;33(4):217–32.
• Palmeri ML, Wang MH, Rouze NC, Abdelmalek MF, Guy CD, Moser B, et al. Noninvasive evaluation of hepatic fibrosis using acoustic radiation force-based shear stiffness in patients with nonalcoholic fatty liver disease. J Hepatol. 2011 Sep;55(3):666–72.
• Palmeri ML, Nightingale KR. Acoustic radiation force-based elasticity imaging methods. Interface focus. 2011 Aug;1(4):553–64.
• Palmeri ML, Nightingale KR. What challenges must be overcome before ultrasound elasticity imaging is ready for the clinic? Imaging in medicine. 2011 Aug;3(4):433–44.
• Bouchard RR, Hsu SJ, Palmeri ML, Rouze NC, Nightingale KR, Trahey GE. Acoustic radiation force-driven assessment of myocardial elasticity using the displacement ratio rate (DRR) method. Ultrasound in medicine & biology. 2011 Jul;37(7):1087–100.
• Rosenzweig S, Palmeri M, Nightingale K. GPU-based real-time small displacement estimation with ultrasound. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2011 Feb;58(2):399–405.
• Nightingale K, Palmeri M, Rouze N, Rosenzweig S, Wang M, Trahey G. TU‐G‐220‐01: Quantitative Elasticity Imaging with Acoustic Radiation Force Induced Shear Waves. In: Medical Physics. 2011. p. 3788–9.
• Rotemberg V, Palmeri M, Rosenzweig S, Grant S, Macleod D, Nightingale K. Acoustic Radiation Force Impulse (ARFI) imaging-based needle visualization. Ultrason Imaging. 2011 Jan;33(1):1–16.
• Rouze NC, Wang MH, Palmeri ML, Nightingale KR. Robust estimation of time-of-flight shear wave speed using a radon sum transformation. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2010 Dec;57(12):2662–70.
• Palmeri ML, Rouze NC, Wang MH, Ding X, Nightingale KR. Quantifying the impact of shear wavelength and kernel size on shear wave speed estimation. In: Proceedings - IEEE Ultrasonics Symposium. 2010. p. 13–6.
• Wang MH, Palmeri ML, Rouze NC, Xu D, Nightingale KR. Improving precision of tissue shear modulus quantification within theregion of acoustic radiation force excitation with compounded displacementestimates. In: Proceedings - IEEE Ultrasonics Symposium. 2010. p. 1600–3.
• Rouze NC, Wang MH, Palmeri ML, Nightingale KR. Robust estimation of time-of-flight shear wave speed using a Radon sum transformation. Proceedings - IEEE Ultrasonics Symposium. 2010 Dec 1;21–4.
• Howles GP, Bing KF, Qi Y, Rosenzweig SJ, Nightingale KR, Johnson GA. Contrast-enhanced in vivo magnetic resonance microscopy of the mouse brain enabled by noninvasive opening of the blood-brain barrier with ultrasound. Magn Reson Med. 2010 Oct;64(4):995–1004.
• Zhai L, Madden J, Foo W-C, Mouraviev V, Polascik TJ, Palmeri ML, et al. Characterizing stiffness of human prostates using acoustic radiation force. Ultrason Imaging. 2010 Oct;32(4):201–13.
• Zipparo MJ, Bing KF, Nightingale KR. Imaging arrays with improved transmit power capability. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2010 Sep;57(9):2076–90.
• Wang MH, Palmeri ML, Rotemberg VM, Rouze NC, Nightingale KR. Improving the robustness of time-of-flight based shear wave speed reconstruction methods using RANSAC in human liver in vivo. Ultrasound in medicine & biology. 2010 May;36(5):802–13.
• Zhai L, Madden J, Foo W-C, Palmeri ML, Mouraviev V, Polascik TJ, et al. Acoustic radiation force impulse imaging of human prostates ex vivo. Ultrasound Med Biol. 2010 Apr;36(4):576–88.
• Palmeri ML, Xu D, Wang M, Nightingale K. Quantitative images of elastic modulus using tissue dynamics in the region of impulsive acoustic radiation force excitation. ASME International Mechanical Engineering Congress and Exposition, Proceedings. 2010 Jan 1;2:487–91.
• Wang M, Palmeri M, Rouze N, Rotemberg V, Moser B, Guy CD, et al. NON-INVASIVE ASSESSMENT OF LIVER FIBROSIS WITH QUANTITATIVE ACOUSTIC RADIATION FORCE METHODS. In: HEPATOLOGY. JOHN WILEY & SONS INC; 2009. p. 743A-744A.
• Wang MH, Palmeri ML, Guy CD, Yang L, Hedlund LW, Diehl AM, et al. In vivo quantification of liver stiffness in a rat model of hepatic fibrosis with acoustic radiation force. Ultrasound Med Biol. 2009 Oct;35(10):1709–21.
• Bing KF, Howles GP, Qi Y, Palmeri ML, Nightingale KR. Blood-brain barrier (BBB) disruption using a diagnostic ultrasound scanner and Definity in Mice. Ultrasound in medicine & biology. 2009 Aug;35(8):1298–308.
• Palmeri ML, Dahl JJ, MacLeod DB, Grant SA, Nightingale KR. On the feasibility of imaging peripheral nerves using acoustic radiation force impulse imaging. Ultrason Imaging. 2009 Jul;31(3):172–82.
• Bing KF, Rotemberg VM, Palmeri ML, Nightingale KR. Concurrent ARFI imaging and HIFU ablation using a diagnostic transducer array and ultrasound system with custom beam sequences. In: Proceedings - IEEE Ultrasonics Symposium. 2009. p. 65–8.
• Wang MH, Palmeri ML, Rotemberg VM, Rouze NC, Nightingale KR. Robust hepatic shear modulus reconstruction using acoustic radiation force and RANSAC. In: Proceedings - IEEE Ultrasonics Symposium. 2009. p. 169–72.
• Zhai L, Madden J, Mouraviev V, Polascik T, Nightingale K. Correlation between SWEI and ARFI image findings in ex vivo human prostates. In: Proceedings - IEEE Ultrasonics Symposium. 2009. p. 523–6.
• Wang M, Palmeri M, Rouze N, Nightingale K, Hobson M. Investigating the effects of viscosity on focused, impulsive, acoustic radiation force induced shear wave morphology. In: Proceedings - IEEE Ultrasonics Symposium. 2008. p. 647–50.
• Zhai L, Hsu S, Bouchard R, Nightingale K. A combined ARFI sequence for 2D displacement imaging and shear wave velocity mapping. In: Proceedings - IEEE Ultrasonics Symposium. 2008. p. 2013–6.
• Palmeri ML, Xu D, Zhai L, Nightingale KR. Acoustic radiation force based quantification of tissue shear modulus within the region of excitation. In: Proceedings - IEEE Ultrasonics Symposium. 2008. p. 2009–12.
• Zhai L, Dahl J, Madden J, Mouraviev V, Polascik T, Palmeri M, et al. Three-dimensional acoustic radiation force impulse (ARFI) imaging of human prostates in vivo. In: 2008 IEEE Ultrasonics Symposium. IEEE; 2008. p. 540–3.
• Zhai L, Palmeri ML, Bouchard RR, Nightingale RW, Nightingale KR. An integrated indenter-ARFI imaging system for tissue stiffness quantification. Ultrasonic imaging. 2008 Apr;30(2):95–111.
• Palmeri ML, Wang MH, Dahl JJ, Frinkley KD, Nightingale KR. Quantifying hepatic shear modulus in vivo using acoustic radiation force. Ultrasound in medicine & biology. 2008 Apr;34(4):546–58.
• Zhai L, Dahl J, Madden J, Mouraviev V, Polascik T, Palmeri M, et al. Three-dimensional acoustic radiation force impulse (ARFI) imaging of human prostates in vivo. In: Proceedings - IEEE Ultrasonics Symposium. 2008. p. 540–3.
• Frinkley K, Rosenzweig S, Nightingale K. Therapeutic potential metric for diagnostic transducers. In: Proceedings - IEEE Ultrasonics Symposium. 2007. p. 116–9.
• Palmeri ML, Wang MH, Frinkley KD, Nightingale KR, Abdelmalek MF, Diehl AM. Dependence of in vivo, radiation force derived hepatic shear modulus estimates on imaging approach: Intercostal vs. subcostal. Proceedings - IEEE Ultrasonics Symposium. 2007 Dec 1;566–9.
• Zhai L, Madden J, Mouraviev V, Polascik T, Nightingale K. Visualizing the anatomic structures of human prostates using Acoustic Radiation Force Impulse (ARFI) imaging. In: Proceedings - IEEE Ultrasonics Symposium. 2007. p. 432–5.
• Wang MH, Hedlund LW, Palmeri ML, Guy CD, Yang L, Diehl AM, et al. In-vivo staging of liver fibrosis in a rat model using acoustic radiation force. Proceedings - IEEE Ultrasonics Symposium. 2007 Dec 1;562–5.
• Huettel LG, Forbes J, Franzoni L, Malkin R, Nadeau J, Nightingale K, et al. Transcending the traditional: Using tablet PCs to enhance engineering and computer science instruction. In: Proceedings - Frontiers in Education Conference, FIE. 2007.
• Nightingale K, Fahey B, Hsu S, Frinkley K, Dahl J, Palmeri M, et al. On the potential for guidance of ablation therapy using acoustic radiation force impulse imaging. 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings. 2007 Nov 27;1116–9.
• Trahey GE, Palmeri M, Nightingale K, Dahl J. Radiation force imaging: Challenges and opportunities. In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2007.
• Dahl JJ, Pinton GF, Palmeri ML, Agrawal V, Nightingale KR, Trahey GE. A parallel tracking method for acoustic radiation force impulse imaging. IEEE Trans Ultrason Ferroelectr Freq Control (USA). 2007;54(2):301–12.
• Huettel LG, Forbes J, Franzoni L, Malkin R, Nadeau J, Nightingale K, et al. Transcending the traditional: Using Tablet PCs to enhance engineering and computer science instruction. In: 2007 37TH ANNUAL FRONTIERS IN EDUCATION CONFERENCE, GLOBAL ENGINEERING : KNOWLEDGE WITHOUT BORDERS - OPPORTUNITIES WITHOUT PASSPORTS, VOLS 1- 4. IEEE; 2007. p. 1724–9.
• Palmeri M, Frinkley K, Oldenburg K, Nightingale K. Characterizing acoustic attenuation using focused impulsive acoustic radiation force. In: Proceedings - IEEE Ultrasonics Symposium. 2006. p. 1680–5.
• Nightingale KR, Zhai L, Dahl JJ, Frinkley KD, Palmeri ML. Shear wave velocity estimation using acoustic radiation force impulsive excitation in liver In Vivo. Proceedings - IEEE Ultrasonics Symposium. 2006 Dec 1;1:1156–60.
• Palmeri ML, McAleavey SA, Fong KL, Trahey GE, Nightingale KR. Dynamic mechanical response of elastic spherical inclusions to impulsive acoustic radiation force excitation. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2006 Nov;53(11):2065–79.
• Palmeri ML, McAleavey SA, Trahey GE, Nightingale KR. Ultrasonic tracking of acoustic radiation force-induced displacements in homogeneous media. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2006 Jul;53(7):1300–13.
• Soo MS, Ghate SV, Baker JA, Rosen EL, Walsh R, Warwick BN, et al. Streaming detection for evaluation of indeterminate sonographic breast masses: a pilot study. AJR Am J Roentgenol. 2006 May;186(5):1335–41.
• Palmeri ML, Frinkley KD, Oldenburg KG, Nightingale KR. Characterizing acoustic attenuation of homogeneous media using focused impulsive acoustic radiation force. Ultrasonic imaging. 2006 Apr;28(2):114–28.
• Paschal CB, Nightingale KR, Ropella KM. Undergraduate biomedical imaging education. Annals of biomedical engineering. 2006 Feb;34(2):232–8.
• Nightingale K, Palmeri M, Trahey G. Analysis of contrast in images generated with transient acoustic radiation force. Ultrasound in medicine & biology. 2006 Jan;32(1):61–72.
• Frinkley K, Palmeri M, Nightingale K. Controlled spatio-temporal heating patterns using a commercial, diagnostic ultrasound system. In: Proceedings - IEEE Ultrasonics Symposium. 2005. p. 1130–4.
• Zhai L, Palmeri M, Nightingale R, Gottfried M, Ludwig K, Nightingale K. A combined indenter/ARFI imaging system. Proceedings - IEEE Ultrasonics Symposium. 2005 Dec 1;1:609–12.
• Palmeri ML, Sharma AC, Bouchard RR, Nightingale RW, Nightingale KR. A finite-element method model of soft tissue response to impulsive acoustic radiation force. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2005 Oct;52(10):1699–712.
• Sharma A, Trahey G, Frinkley K, Soo MS, Palmeri M, Nightingale K. Image processing and data acquisition optimization for Acoustic Radiation Force Impulse imaging of in vivo breast masses. In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2005. p. 205–15.
• Fahey BJ, Nightingale KR, Nelson RC, Palmeri ML, Trahey GE. Acoustic radiation force impulse imaging of the abdomen: demonstration of feasibility and utility. Ultrasound Med Biol. 2005 Sep;31(9):1185–98.
• Fahey BJ, Nightingale KR, McAleavey SA, Palmeri ML, Wolf PD, Trahey GE. Acoustic radiation force impulse imaging of myocardial radiofrequency ablation: initial in vivo results. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2005 Apr;52(4):631–41.
• Palmeri ML, Frinkley KD, Zhai L, Gottfried M, Bentley RC, Ludwig K, et al. Acoustic radiation force impulse (ARFI) imaging of the gastrointestinal tract. Ultrason Imaging. 2005 Apr;27(2):75–88.
• Nightingale K, Palmeri M, Frinkley K, Sharma A, Zhai L, Trahey G. Ultrasonic imaging of the mechanical properties of tissues using localized, transient acoustic radiation FORCE. In: ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings. 2005. p. 981–4.
• Pinton GF, McAleavey SA, Dahl JJ, Nightingale KR, Trahey GE. Real-time acoustic radiation force impulse imaging. In: Proc SPIE - Int Soc Opt Eng (USA). 2005. p. 226–35.
• Soo MS, Baker JA, Ghate SV, Walsh R, Warwick B, Nightingale K. Streaming detection for evaluation of indeterminate sono-graphic breast masses - A pilot study. In: AMERICAN JOURNAL OF ROENTGENOLOGY. AMER ROENTGEN RAY SOC; 2005. p. 27–27.
• Sharma AC, Soo MS, Trahey GE, Nightingale KR. Acoustic radiation force impulse imaging of in vivo breast masses. In: Proceedings - IEEE Ultrasonics Symposium. 2004. p. 728–31.
• Trahey GE, Palmeri ML, Bentley RC, Nightingale KR. Acoustic radiation force impulse imaging of the mechanical properties of arteries: in vivo and ex vivo results. Ultrasound Med Biol. 2004 Sep;30(9):1163–71.
• Palmeri ML, Nightingale KR. On the thermal effects associated with radiation force imaging of soft tissue. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2004 May 1;51(5):551–65.
• Palmeri ML, Nightingale KR. On the thermal effects associated with radiation force imaging of soft tissue. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2004 May;51(5):551–65.
• Palmeri ML, Frinkley KD, Nightingale KR. Experimental studies of the thermal effects associated with radiation force imaging of soft tissue. Ultrasonic imaging. 2004 Apr;26(2):100–14.
• Fahey BJ, Nightingale KR, Stutz DL, Trahey GE. Acoustic radiation force impulse imaging of thermally- and chemically-induced lesions in soft tissues: preliminary ex vivo results. Ultrasound in medicine & biology. 2004 Mar;30(3):321–8.
• Palmeri M, Frinkley K, Zhai L, Bentley R, Ludwig K, Gottfried M, et al. Acoustic Radiation Force Impulse (ARFI) imaging of the gastrointestinal tract. In: Proceedings - IEEE Ultrasonics Symposium. 2004. p. 744–7.
• Nightingale K, Soo MS, Palmeri M, Congdon A, Frinkley K, Trahey G. Imaging tissue mechanical properties using impulsive acoustic radiation force. 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004 Jan 1;1:41–4.
• Fahey BJ, Nightingale KR, Wolf PD, Trahey GE. ARFI imaging of thermal lesions in ex vivo and in vivo soft tissues. In: Proceedings of the IEEE Ultrasonics Symposium. 2003. p. 562–7.
• Palmeri ML, Nightingale KR. Thermal effects associated with acoustic radiation force impulse imaging. In: Proceedings of the IEEE Ultrasonics Symposium. 2003. p. 232–7.
• Pinton GF, Palmeri ML, McAleavey SA, Nightingale KR, Trahey GE. ARFI imaging of the cardiovascular system. Proceedings of the IEEE Ultrasonics Symposium. 2003 Dec 1;1:228–31.
• Nightingale K, Palmeri M, Bouchard R, Trahey G. Acoustic radiation force impulse imaging: A parametric analysis of factors affecting image quality. Proceedings of the IEEE Ultrasonics Symposium. 2003 Dec 1;1:548–53.
• Gallippi CM, Nightingale KR, Trahey GE. Blind source separation-based adaptive filtering of physiological and ARFI-induced tissue, blood, and cyst fluid motion, in-vivo. In: Proceedings of the IEEE Ultrasonics Symposium. 2003. p. 841–6.
• Hsu SJ, Palermi ML, Nightingale KR, McAleavey SA, Dahl JD, Trahey GE. Shear wave anisotropy imaging. In: Proceedings of the IEEE Ultrasonics Symposium. 2003. p. 1090–3.
• Hsu SJ, Palermi ML, Nightingale KR, McAleavey SA, Dahl JD, Trahey GE. Shear wave anisotropy imaging. In: Proceedings of the IEEE Ultrasonics Symposium. 2003. p. 921–4.
• Nightingale K, McAleavey S, Trahey G. Shear-wave generation using acoustic radiation force: in vivo and ex vivo results. Ultrasound in medicine & biology. 2003 Dec;29(12):1715–23.
• Gallippi CM, Nightingale KR, Trahey GE. BSS-based filtering of physiological and ARFI-induced tissue and blood motion. Ultrasound in medicine & biology. 2003 Nov;29(11):1583–92.
• McAleavey SA, Nightingale KR, Stutz DL, Hsu SJ, Trahey GE. Image reconstruction with acoustic radiation force induced shear waves. In: Proceedings of SPIE - The International Society for Optical Engineering. 2003. p. 223–34.
• Trahey GE, Dahl JJ, McAleavey SA, Gallippi CM, Nightingale KR. Arterial stiffness measurements with acoustic radiation force impulse imaging. In: Proceedings of SPIE - The International Society for Optical Engineering. 2003. p. 235–41.
• McAleavey SA, Nightingale KR, Trahey GE. Estimates of echo correlation and measurement bias in acoustic radiation force impulse imaging. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2003 Jun;50(6):631–41.
• Nightingale K, Bentley R, Trahey G. Observations of tissue response to acoustic radiation force: opportunities for imaging. Ultrason Imaging. 2002 Jul;24(3):129–38.
• Nightingale K, Soo MS, Nightingale R, Trahey G. Acoustic radiation force impulse imaging: in vivo demonstration of clinical feasibility. Ultrasound Med Biol. 2002 Feb;28(2):227–35.
• Nightingale K, Nightingale R, Stutz D, Trahey G. Acoustic radiation force impulse imaging of in vivo vastus medialis muscle under varying isometric load. Ultrasonic Imaging. 2002;24(2):100–8.
• Nightingale K, Soo MS, Nightingale R, Bentley R, Stutz D, Palmeri M, et al. Acoustic radiation force impulse imaging: Remote palpation of the mechanical properties of tissue. Proceedings of the IEEE Ultrasonics Symposium. 2002;2:1821–30.
• Nightingale K, Stutz D, Bentley R, Trahey G. Acoustic radiation force impulse imaging: EX vivo and in vivo demonstration of transient shear wave propagation. In: Proceedings - International Symposium on Biomedical Imaging. 2002. p. 525–8.
• Nightingale K, Nightingale R, Trahey G. Evaluation of the mechanical properties of active skeletal muscle using acoustic radiation force impulse imaging. Proceedings of the IEEE Ultrasonics Symposium. 2001 Dec 1;2:1627–31.
• Nightingale KR, Palmeri ML, Nightingale RW, Trahey GE. On the feasibility of remote palpation using acoustic radiation force. J Acoust Soc Am. 2001 Jul;110(1):625–34.
• Nightingale K, Soo MS, Nightingale R, Bentley R, Trahey G. In vivo demonstration of acoustic radiation force impulse (ARFI) imaging in the thyroid, abdomen, and breast. Proceedings of the IEEE Ultrasonics Symposium. 2001;2:1633–8.
• Nightingale KR, Soo MS, Nightingale RW, Trahey GE. Investigation of real-time remote palpation imaging. Proceedings of SPIE - The International Society for Optical Engineering. 2001 Jan 1;4325:113–9.
• Nightingale K, Palmeri M, Nightingale R, Trahey G. Acoustic remote palpation: Initial in vivo results. In: Proceedings of the IEEE Ultrasonics Symposium. 2000. p. 1553–8.
• Nightingale KR, Trahey GE. A finite element model for simulating acoustic streaming in cystic breast lesions with experimental validation. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2000 Jan;47(1):201–14.
• Nightingale KR, Nightingale RW, Palmeri ML, Trahey GE. A finite element model of remote palpation of breast lesions using radiation force: factors affecting tissue displacement. Ultrasonic imaging. 2000 Jan;22(1):35–54.
• Nightingale K, Nightingale R, Palmeri M, Trahey G. Finite element analysis of radiation force induced tissue motion with experimental validation. In: Proceedings of the IEEE Ultrasonics Symposium. 1999. p. 1319–23.
• Nightingale KR, Kornguth PJ, Trahey GE. The use of acoustic streaming in breast lesion diagnosis: a clinical study. Ultrasound in medicine & biology. 1999 Jan;25(1):75–87.
• Friemel BH, Bohs LN, Nightingale KR, Trahey GE. Speckle decorrelation due to two-dimensional flow gradients. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 1998 Jan;45(2):317–27.
• Nightingale K, Kornguth P, Breit S, Liu S, Trahey G. Utilization of acoustic streaming to classify breast lesions in vivo. In: Proceedings of the IEEE Ultrasonics Symposium. 1997. p. 1419–22.
• Dayton PA, Morgan KE, Klibanov AL, Brandenburger G, Nightingale KR, Ferrara KW. A preliminary evaluation of the effects of primary and secondary radiation forces on acoustic contrast agents. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 1997 Dec 1;44(6):1264–77.
• Nightingale KR, Kornguth PJ, Trahey GE. Streaming detection: improvements in sensitivity. In: Proceedings of the IEEE Ultrasonics Symposium. 1996. p. 1261–4.
• Bohs LN, Geiman BJ, Nightingale KR, Choi CD, Friemel BH, Trahey GE. Ensemble tracking: a new method for 2D vector velocity measurement. Proceedings of the IEEE Ultrasonics Symposium. 1995 Dec 1;2:1485–8.
• Nightingale KR, Kornguth PJ, Walker WF, McDermott BA, Trahey GE. A novel ultrasonic technique for differentiating cysts from solid lesions: preliminary results in the breast. Ultrasound in medicine & biology. 1995 Jan;21(6):745–51.
• Bohs LN, Friemel BH, Kisslo J, Harfe DT, Nightingale KR, Trahey GE. Three-dimensional flow images by reconstruction from two-dimensional vector velocity maps. J Am Soc Echocardiogr. 1995;8(6):915–23.
• Alsberg E, Trahey GE, Bohs LN, Friemel BH, Nightingale KR, Walker WF. Three-dimensional flow visualization via reconstruction from successive two-dimensional vector velocity maps. In: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1994. p. 598–9.
• Nightingale KR, Kornguth PJ, Walker WF, Glasgow SC, Jett EA, Trahey GE. Generation and detection of acoustic streaming to differentiate between solid and cystic breast lesions. Proceedings of the IEEE Ultrasonics Symposium. 1994 Jan 1;3:1653–6.
• Friemel BH, Nightingale KR, Bohs LN, Trahey GE. Wall filtering challenges in two-dimensional vector velocity estimation. In: Proceedings of the IEEE Ultrasonics Symposium. 1993. p. 1031–4.
• Alsberg E, Trahey GE, Bohs LN, Friemel BH, Nightingale KR, Walker WF. Three-dimensional flow visualization via reconstruction from successive two-dimensional vector velocity maps (Accepted). Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. :598–9.

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