Birgit Frauscher
Neurology, Epilepsy and Sleep
Professor of Neurology
Bio
Dr. Birgit Frauscher is a clinician scientist whose career is dedicated to improve diagnosis and prognosis of people with epilepsy by developing new methods based on advanced electroencephalography techniques to better localize the epileptic focus in order to improve epilepsy treatment outcomes and ultimately achieve the best possible quality of life. She is currently holding the position of Director of the Duke Comprehensive Epilepsy Center and holds a secondary appointment with the Department of Biomedical Engineering at the Duke Pratt School of Engineering.
Her academic journey started at the Medical University of Innsbruck in Austria, where she accomplished her medical training, residency in neurology, and subspecialty training in electroencephalography, epilepsy and sleep medicine. Early in her career during Medical School she became fascinated by the technique of electroencephalography and how it allows to draw important conclusions on brain function. After completion of her clinical training in 2008, she underwent subsequent research training resulting in the successful completion of her habilitation degree in 2011. To specialize on intracranial EEG and signal analysis, she spent a visiting professorship at the Montreal Neurological Institute and Hospital, McGill University in Canada between 2013 – 2015. Subsequently, she served at the Montreal Neurological Institute and Hospital as an Attending Epileptologist and later as Group Leader of Epilepsy and Professor of Neurology.
Her research interests include i) the development of novel seizure-independent EEG markers for the epileptogenic zone in order to achieve a more accurate diagnosis of epilepsy, ii) the investigation of the important interactions between sleep and epilepsy, and iii) the use of the unique possibility of invasive intracranial EEG for studying brain physiology during wakefulness and sleep in order to better delineate normal from abnormal intracranial EEG activity.
Dr. Frauscher’s publication record holds over 170 peer-reviewed papers dedicated to epilepsy and sleep with a H-index of 62. Her scholarly endeavors have earned her several prestigious awards, including Clinician-Scientist awards of the FRSQ (2018-2023), the Michael Prize of the International League against Epilepsy (2019) and the Ernst Niedermeyer Prize from the Austrian Epilepsy Society (2015). Dr. Frauscher's dedication to pushing the boundaries of epilepsy and sleep research highlights her standing in the field and her significant contributions to advancing clinical knowledge.
Education
- M.D. University of Innsbruck (Austria), 2001
Trainings & Certifications
- Neurology Residency Program (included a two-year fellowship in clinical neurophysiology, epilepsy, and sleep), Innsbruck Medi, NEUROLOGY (2002 - 2008) University of Innsbruck (Austria)
Positions
- Professor of Neurology
- Director of the Epilepsy Lab in the Department of Neurology
- Professor of Biomedical Engineering
Publications
- Wadi L, Khweileh M, Agashe S, Southwell D, Parikh P, Frauscher B. Sleep-related hypermotor seizures originating from the occipital lobe. Epileptic Disord. 2024 Sep 21;
- Klimes P, Nejedly P, Hrtonova V, Cimbalnik J, Travnicek V, Pail M, et al. Interictal stereo-electroencephalography features below 45 Hz are sufficient for correct localization of the epileptogenic zone and postsurgical outcome prediction. Epilepsia. 2024 Aug 24;
- Latreille V, Corbin-Lapointe J, Peter-Derex L, Thomas J, Lina J-M, Frauscher B. Oscillatory and nonoscillatory sleep electroencephalographic biomarkers of the epileptic network. Epilepsia. 2024 Aug 24;
- Wei X, Avigdor T, Ho A, Minato E, Garcia-Asensi A, Royer J, et al. ANPHY-Sleep: an Open Sleep Database from Healthy Adults Using High-Density Scalp Electroencephalogram. Sci Data. 2024 Aug 17;11(1):896.
- Mansilla D, Tveit J, Aurlien H, Avigdor T, Ros-Castello V, Ho A, et al. Generalizability of electroencephalographic interpretation using artificial intelligence: An external validation study. Epilepsia. 2024 Aug 14;
- Ngo A, Royer J, Rodriguez-Cruces R, Xie K, DeKraker J, Auer H, et al. Associations of Cerebral Blood Flow Patterns With Gray and White Matter Structure in Patients With Temporal Lobe Epilepsy. Neurology. 2024 Aug 13;103(3):e209528.
- Thomas J, Abdallah C, Cai Z, Jaber K, Gotman J, Beniczky S, et al. Investigating current clinical opinions in stereoelectroencephalography-informed epilepsy surgery. Epilepsia. 2024 Aug 3;
- Schiller K, Thomas J, Avigdor T, Mansilla D, Kortas A, Unterholzner G, et al. Pulsatile corticoid therapy reduces interictal epileptic activity burden in children with genetic drug-resistant epilepsy. Epilepsia Open. 2024 Aug;9(4):1265–76.
- Afnan J, Cai Z, Lina J-M, Abdallah C, Delaire E, Avigdor T, et al. EEG/MEG source imaging of deep brain activity within the maximum entropy on the mean framework: Simulations and validation in epilepsy. Hum Brain Mapp. 2024 Jul 15;45(10):e26720.
- Larivière S, Park B-Y, Royer J, DeKraker J, Ngo A, Sahlas E, et al. Connectome reorganization associated with temporal lobe pathology and its surgical resection. Brain. 2024 Jul 5;147(7):2483–95.
- Shi W, Shaw D, Walsh KG, Han X, Eden UT, Richardson RM, et al. Spike ripples localize the epileptogenic zone best: an international intracranial study. Brain. 2024 Jul 5;147(7):2496–506.
- Abdallah C, Mansilla D, Minato E, Grova C, Beniczky S, Frauscher B. Systematic review of seizure-onset patterns in stereo-electroencephalography: Current state and future directions. Clin Neurophysiol. 2024 Jul;163:112–23.
- Hannan S, Ho A, Frauscher B. Clinical Utility of Sleep Recordings During Presurgical Epilepsy Evaluation With Stereo-Electroencephalography: A Systematic Review. J Clin Neurophysiol. 2024 Jul 1;41(5):430–43.
- Kalamangalam G, Frauscher B. The SEEG Wave. J Clin Neurophysiol. 2024 Jul 1;41(5):397–8.
- Jaber K, Avigdor T, Mansilla D, Ho A, Thomas J, Abdallah C, et al. A spatial perturbation framework to validate implantation of the epileptogenic zone. Nat Commun. 2024 Jun 19;15(1):5253.
- Tavakol S, Kebets V, Royer J, Li Q, Auer H, DeKraker J, et al. Differential relational memory impairment in temporal lobe epilepsy. Epilepsy Behav. 2024 Jun;155:109722.
- Chybowski B, Klimes P, Cimbalnik J, Travnicek V, Nejedly P, Pail M, et al. Timing matters for accurate identification of the epileptogenic zone. Clin Neurophysiol. 2024 May;161:1–9.
- Xie K, Royer J, Larivière S, Rodriguez-Cruces R, Frässle S, Cabalo DG, et al. Atypical connectome topography and signal flow in temporal lobe epilepsy. Prog Neurobiol. 2024 May;236:102604.
- Ryvlin P, Barba C, Bartolomei F, Baumgartner C, Brazdil M, Fabo D, et al. Grading system for assessing the confidence in the epileptogenic zone reported in published studies: A Delphi consensus study. Epilepsia. 2024 May;65(5):1346–59.
- Wang YL, Avigdor T, Hannan S, Abdallah C, Dubeau F, Peter-Derex L, et al. Intracerebral Dynamics of Sleep Arousals: A Combined Scalp-Intracranial EEG Study. J Neurosci. 2024 Apr 17;44(16).
- Frauscher B, Rossetti AO, Beniczky S. Recent advances in clinical electroencephalography. Curr Opin Neurol. 2024 Apr 1;37(2):134–40.
- Latreille V, Avigdor T, Thomas J, Crane J, Sziklas V, Jones-Gotman M, et al. Scalp and hippocampal sleep correlates of memory function in drug-resistant temporal lobe epilepsy. Sleep. 2024 Feb 8;47(2).
- Avigdor T, Abdallah C, Afnan J, Cai Z, Rammal S, Grova C, et al. Consistency of electrical source imaging in presurgical evaluation of epilepsy across different vigilance states. Ann Clin Transl Neurol. 2024 Feb;11(2):389–403.
- Frauscher B, Mansilla D, Abdallah C, Astner-Rohracher A, Beniczky S, Brazdil M, et al. Learn how to interpret and use intracranial EEG findings. Epileptic Disord. 2024 Feb;26(1):1–59.
- Bernard C, Frauscher B, Gelinas J, Timofeev I. Sleep, oscillations, and epilepsy. Epilepsia. 2023 Dec;64 Suppl 3(Suppl 3):S3–12.
- Horrillo-Maysonnial A, Avigdor T, Abdallah C, Mansilla D, Thomas J, von Ellenrieder N, et al. Targeted density electrode placement achieves high concordance with traditional high-density EEG for electrical source imaging in epilepsy. Clin Neurophysiol. 2023 Dec;156:262–71.
- Frauscher B, Bartolomei F, Baud MO, Smith RJ, Worrell G, Lundstrom BN. Stimulation to probe, excite, and inhibit the epileptic brain. Epilepsia. 2023 Dec;64 Suppl 3(Suppl 3):S49–61.
- Ho A, Hannan S, Thomas J, Avigdor T, Abdallah C, Dubeau F, et al. Rapid eye movement sleep affects interictal epileptic activity differently in mesiotemporal and neocortical areas. Epilepsia. 2023 Nov;64(11):3036–48.
- Sklenarova B, Zatloukalova E, Cimbalnik J, Klimes P, Dolezalova I, Pail M, et al. Interictal high-frequency oscillations, spikes, and connectivity profiles: A fingerprint of epileptogenic brain pathologies. Epilepsia. 2023 Nov;64(11):3049–60.
- Hannan S, Thomas J, Jaber K, El Kosseifi C, Ho A, Abdallah C, et al. The Differing Effects of Sleep on Ictal and Interictal Network Dynamics in Drug-Resistant Epilepsy. Ann Neurol. 2023 Sep 15;
- Royer J, Larivière S, Rodriguez-Cruces R, Cabalo DG, Tavakol S, Auer H, et al. Cortical microstructural gradients capture memory network reorganization in temporal lobe epilepsy. Brain. 2023 Sep 1;146(9):3923–37.
- Ibrahim A, Ferri R, Cesari M, Frauscher B, Heidbreder A, Bergmann M, et al. Large muscle group movements during sleep in healthy people: normative values and correlation to sleep features. Sleep. 2023 Aug 14;46(8).
- Afnan J, von Ellenrieder N, Lina J-M, Pellegrino G, Arcara G, Cai Z, et al. Validating MEG source imaging of resting state oscillatory patterns with an intracranial EEG atlas. Neuroimage. 2023 Jul 1;274:120158.
- Peter-Derex L, von Ellenrieder N, van Rosmalen F, Hall J, Dubeau F, Gotman J, et al. Regional variability in intracerebral properties of NREM to REM sleep transitions in humans. Proc Natl Acad Sci U S A. 2023 Jun 27;120(26):e2300387120.
- Peter-Derex L, Avigdor T, Rheims S, Guénot M, von Ellenrieder N, Gotman J, et al. Enhanced thalamocortical functional connectivity during rapid-eye-movement sleep sawtooth waves. Sleep. 2023 Jun 13;46(6).
- Frauscher B, Bénar CG, Engel JJ, Grova C, Jacobs J, Kahane P, et al. Neurophysiology, Neuropsychology, and Epilepsy, in 2022: Hills We Have Climbed and Hills Ahead. Neurophysiology in epilepsy. Epilepsy Behav. 2023 Jun;143:109221.
- Travnicek V, Klimes P, Cimbalnik J, Frauscher B. Response: Can biomarkers of the epileptogenic zone be characterized in patients rendered seizure free alone? Epilepsia. 2023 Jun;64(6):1695.
- Zelmann R, Frauscher B, Aro RP, Gueziri H-E, Collins DL. SEEGAtlas: A framework for the identification and classification of depth electrodes using clinical images. J Neural Eng. 2023 May 31;20(3).
- Travnicek V, Klimes P, Cimbalnik J, Halamek J, Jurak P, Brinkmann B, et al. Relative entropy is an easy-to-use invasive electroencephalographic biomarker of the epileptogenic zone. Epilepsia. 2023 Apr;64(4):962–72.
- Xie K, Royer J, Lariviere S, Rodriguez-Cruces R, de Wael RV, Park B-Y, et al. Atypical intrinsic neural timescales in temporal lobe epilepsy. Epilepsia. 2023 Apr;64(4):998–1011.
- Thomas J, Kahane P, Abdallah C, Avigdor T, Zweiphenning WJEM, Chabardes S, et al. A Subpopulation of Spikes Predicts Successful Epilepsy Surgery Outcome. Ann Neurol. 2023 Mar;93(3):522–35.
- Schiller K, von Ellenrieder N, Avigdor T, El Kosseifi C, Abdallah C, Minato E, et al. Focal epilepsy impacts rapid eye movement sleep microstructure. Sleep. 2023 Feb 8;46(2).
- Azeem A, von Ellenrieder N, Royer J, Frauscher B, Bernhardt B, Gotman J. Integration of white matter architecture to stereo-EEG better describes epileptic spike propagation. Clin Neurophysiol. 2023 Feb;146:135–46.
- Eckhardt C, Fanciulli A, Högl B, Heidbreder A, Eschlböck S, Raccagni C, et al. Analysis of sleep, daytime sleepiness, and autonomic function in multiple system atrophy and Parkinson disease: a prospective study. J Clin Sleep Med. 2023 Jan 1;19(1):63–71.
- Latreille V, Schiller K, Peter-Derex L, Frauscher B. Does epileptic activity impair sleep-related memory consolidation in epilepsy? A critical and systematic review. J Clin Sleep Med. 2022 Oct 1;18(10):2481–95.
- Royer J, Rodríguez-Cruces R, Tavakol S, Larivière S, Herholz P, Li Q, et al. An Open MRI Dataset For Multiscale Neuroscience. Sci Data. 2022 Sep 15;9(1):569.
- Dinkelacker V, El Helou J, Frauscher B. Interictal sleep recordings during presurgical evaluation: Bidirectional perspectives on sleep related network functioning. Rev Neurol (Paris). 2022 Sep;178(7):703–13.
- Nobili L, Frauscher B, Eriksson S, Gibbs SA, Halasz P, Lambert I, et al. Sleep and epilepsy: A snapshot of knowledge and future research lines. J Sleep Res. 2022 Aug;31(4):e13622.
- Schiller K, Avigdor T, Abdallah C, Sziklas V, Crane J, Stefani A, et al. Focal epilepsy disrupts spindle structure and function. Sci Rep. 2022 Jul 1;12(1):11137.
- Abdallah C, Hedrich T, Koupparis A, Afnan J, Hall JA, Gotman J, et al. Clinical Yield of Electromagnetic Source Imaging and Hemodynamic Responses in Epilepsy: Validation With Intracerebral Data. Neurology. 2022 Jun 13;98(24):e2499–511.
- von Ellenrieder N, Peter-Derex L, Gotman J, Frauscher B. SleepSEEG: automatic sleep scoring using intracranial EEG recordings only. J Neural Eng. 2022 May 3;19(2).
- Serlin Y, Alshahrani M, Frauscher B. Provocative Hyperventilation in a Patient With Stroke-Like Migraine Attacks After Radiation Therapy. JAMA neurology. 2022 May;79(5):526–7.
- Kokkinos V, Urban A, Frauscher B, Simon M, Hussein H, Bush A, et al. Barques are generated in posterior hippocampus and phase reverse over lateral posterior hippocampal surface. Clin Neurophysiol. 2022 Apr;136:150–7.
- Zhang H, Iranzo A, Högl B, Arnulf I, Ferini-Strambi L, Manni R, et al. Risk Factors for Phenoconversion in Rapid Eye Movement Sleep Behavior Disorder. Ann Neurol. 2022 Mar;91(3):404–16.
- Zweiphenning WJEM, von Ellenrieder N, Dubeau F, Martineau L, Minotti L, Hall JA, et al. Correcting for physiological ripples improves epileptic focus identification and outcome prediction. Epilepsia. 2022 Feb;63(2):483–96.
- Klimes P, Peter-Derex L, Hall J, Dubeau F, Frauscher B. Spatio-temporal spike dynamics predict surgical outcome in adult focal epilepsy. Clin Neurophysiol. 2022 Feb;134:88–99.
- Delgado-Garcia G, Frauscher B. Future of Neurology & Technology: Stereoelectroencephalography in Presurgical Epilepsy Evaluation. Neurology. 2022 Jan 24;98(4):e437–40.
- Olejarczyk E, Gotman J, Frauscher B. Region-specific complexity of the intracranial EEG in the sleeping human brain. Sci Rep. 2022 Jan 10;12(1):451.
- Dimakopoulos V, Gotman J, Stacey W, Von Ellenrieder N, Jacobs J, Papadelis C, et al. Protocol for multicentre comparison of interictal high-frequency oscillations as a predictor of seizure freedom. Brain Communications. 2022 Jan 1;4(3).
- Astner-Rohracher A, Zimmermann G, Avigdor T, Abdallah C, Barot N, Brázdil M, et al. Development and Validation of the 5-SENSE Score to Predict Focality of the Seizure-Onset Zone as Assessed by Stereoelectroencephalography. JAMA Neurol. 2022 Jan 1;79(1):70–9.
- Kokkinos V, Hussein H, Frauscher B, Simon M, Urban A, Bush A, et al. Hippocampal spindles and barques are normal intracranial electroencephalographic entities. Clin Neurophysiol. 2021 Dec;132(12):3002–9.
- de la Chapelle A, Frauscher B, Valomon A, Ruby PM, Peter-Derex L. Relationship Between Epilepsy and Dreaming: Current Knowledge, Hypotheses, and Perspectives. Frontiers in Neuroscience. 2021 Sep 6;15.
- Li Q, Tavakol S, Royer J, Larivière S, Vos De Wael R, Park B-Y, et al. Atypical neural topographies underpin dysfunctional pattern separation in temporal lobe epilepsy. Brain. 2021 Sep 4;144(8):2486–98.
- Azeem A, von Ellenrieder N, Hall J, Dubeau F, Frauscher B, Gotman J. Interictal spike networks predict surgical outcome in patients with drug-resistant focal epilepsy. Ann Clin Transl Neurol. 2021 Jun;8(6):1212–23.
- Tuovinen N, Stefani A, Mitterling T, Heidbreder A, Frauscher B, Gizewski ER, et al. Functional connectivity and topology in patients with restless legs syndrome: a case-control resting-state functional magnetic resonance imaging study. Eur J Neurol. 2021 Feb;28(2):448–58.
- Avigdor T, Abdallah C, von Ellenrieder N, Hedrich T, Rubino A, Lo Russo G, et al. Fast oscillations >40 Hz localize the epileptogenic zone: An electrical source imaging study using high-density electroencephalography. Clin Neurophysiol. 2021 Feb;132(2):568–80.
- Cesari M, Stefani A, Mitterling T, Frauscher B, Schönwald SV, Högl B. Sleep modelled as a continuous and dynamic process predicts healthy ageing better than traditional sleep scoring. Sleep Med. 2021 Jan;77:136–46.
- Frauscher B, von Ellenrieder N, Dolezalova I, Bouhadoun S, Gotman J, Peter-Derex L. Rapid Eye Movement Sleep Sawtooth Waves Are Associated with Widespread Cortical Activations. J Neurosci. 2020 Nov 11;40(46):8900–12.
- Bergmann M, Prieschl M, Stefani A, Heidbreder A, Walser G, Frauscher B, et al. A prospective controlled study about sleep disorders in drug resistant epilepsy. Sleep Med. 2020 Nov;75:434–40.
- Paquola C, Seidlitz J, Benkarim O, Royer J, Klimes P, Bethlehem RAI, et al. A multi-scale cortical wiring space links cellular architecture and functional dynamics in the human brain. PLoS Biol. 2020 Nov;18(11):e3000979.
- Peter-Derex L, Klimes P, Latreille V, Bouhadoun S, Dubeau F, Frauscher B. Sleep Disruption in Epilepsy: Ictal and Interictal Epileptic Activity Matter. Ann Neurol. 2020 Nov;88(5):907–20.
- Nevalainen P, von Ellenrieder N, Klimeš P, Dubeau F, Frauscher B, Gotman J. Association of fast ripples on intracranial EEG and outcomes after epilepsy surgery. Neurology. 2020 Oct 20;95(16):e2235–45.
- Royer J, Paquola C, Larivière S, Vos de Wael R, Tavakol S, Lowe AJ, et al. Myeloarchitecture gradients in the human insula: Histological underpinnings and association to intrinsic functional connectivity. Neuroimage. 2020 Aug 1;216:116859.
- Jobst BC, Bartolomei F, Diehl B, Frauscher B, Kahane P, Minotti L, et al. Intracranial EEG in the 21st Century. Epilepsy Currents. 2020 Jul 1;20(4):180–8.
- Larivière S, Weng Y, Vos de Wael R, Royer J, Frauscher B, Wang Z, et al. Functional connectome contractions in temporal lobe epilepsy: Microstructural underpinnings and predictors of surgical outcome. Epilepsia. 2020 Jun;61(6):1221–33.
- Latreille V, von Ellenrieder N, Peter-Derex L, Dubeau F, Gotman J, Frauscher B. The human K-complex: Insights from combined scalp-intracranial EEG recordings. Neuroimage. 2020 Jun;213:116748.
- Frauscher B. Localizing the epileptogenic zone. Curr Opin Neurol. 2020 Apr;33(2):198–206.
- von Ellenrieder N, Gotman J, Zelmann R, Rogers C, Nguyen DK, Kahane P, et al. How the Human Brain Sleeps: Direct Cortical Recordings of Normal Brain Activity. Ann Neurol. 2020 Feb;87(2):289–301.
- Mooij AH, Frauscher B, Gotman J, Huiskamp GJM. A skew-based method for identifying intracranial EEG channels with epileptic activity without detecting spikes, ripples, or fast ripples. Clin Neurophysiol. 2020 Jan;131(1):183–92.
- Stefani A, Mitterling T, Heidbreder A, Steiger R, Kremser C, Frauscher B, et al. Multimodal Magnetic Resonance Imaging reveals alterations of sensorimotor circuits in restless legs syndrome. Sleep. 2019 Dec 24;42(12).
- Klimes P, Cimbalnik J, Brazdil M, Hall J, Dubeau F, Gotman J, et al. NREM sleep is the state of vigilance that best identifies the epileptogenic zone in the interictal electroencephalogram. Epilepsia. 2019 Dec;60(12):2404–15.
- Cuello Oderiz C, von Ellenrieder N, Dubeau F, Eisenberg A, Gotman J, Hall J, et al. Association of Cortical Stimulation-Induced Seizure With Surgical Outcome in Patients With Focal Drug-Resistant Epilepsy. JAMA Neurol. 2019 Sep 1;76(9):1070–8.
- Frauscher B, Gotman J. Sleep, oscillations, interictal discharges, and seizures in human focal epilepsy. Neurobiol Dis. 2019 Jul;127:545–53.
- Schönberger J, Frauscher B, von Ellenrieder N, Avoli M, Dubeau F, Gotman J. Fast ripple analysis in human mesial temporal lobe epilepsy suggests two different seizure-generating mechanisms. Neurobiol Dis. 2019 Jul;127:374–81.
- Amiri M, Frauscher B, Gotman J. Interictal coupling of HFOs and slow oscillations predicts the seizure-onset pattern in mesiotemporal lobe epilepsy. Epilepsia. 2019 Jun;60(6):1160–70.
- Haschka D, Volani C, Stefani A, Tymoszuk P, Mitterling T, Holzknecht E, et al. Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome. Mov Disord. 2019 Jan;34(1):114–23.
- Thomschewski A, Hincapié AS, Frauscher B. Localization of the epileptogenic zone using high frequency oscillations. Frontiers in Neurology. 2019 Jan 1;10(FEB).
- Mooij AH, Frauscher B, Goemans SAM, Huiskamp GJM, Braun KPJ, Zijlmans M. Ripples in scalp EEGs of children: co-occurrence with sleep-specific transients and occurrence across sleep stages. Sleep. 2018 Nov 1;41(11).
- Stefani A, Frauscher B, Högl B. Diagnosis of REM sleep behavior disorder. In: Rapid-eye-movement sleep behavior disorder. 2018. p. 245–54.
- Frauscher B, von Ellenrieder N, Zelmann R, Rogers C, Nguyen DK, Kahane P, et al. High-Frequency Oscillations in the Normal Human Brain. Ann Neurol. 2018 Sep;84(3):374–85.
- Frauscher B, Joshi S, von Ellenrieder N, Nguyen DK, Dubeau F, Gotman J. Sharply contoured theta waves are the human correlate of ponto-geniculo-occipital waves in the primary visual cortex. Clin Neurophysiol. 2018 Aug;129(8):1526–33.
- von Ellenrieder N, Dan J, Frauscher B, Gotman J. Corrigendum to "Sparse asynchronous cortical generators can produce measurable scalp EEG signals" [Neuroimage 138 (2016) 123-133]. NeuroImage. 2018 May;172:631.
- Frauscher B, von Ellenrieder N, Zelmann R, Doležalová I, Minotti L, Olivier A, et al. Atlas of the normal intracranial electroencephalogram: neurophysiological awake activity in different cortical areas. Brain. 2018 Apr 1;141(4):1130–44.
- Auer M, Frauscher B, Hochleitner M, Högl B. Gender-Specific Differences in Access to Polysomnography and Prevalence of Sleep Disorders. J Womens Health (Larchmt). 2018 Apr;27(4):525–30.
- Haba-Rubio J, Frauscher B, Marques-Vidal P, Toriel J, Tobback N, Andries D, et al. Prevalence and determinants of rapid eye movement sleep behavior disorder in the general population. Sleep. 2018 Feb 1;41(2).
- Frauscher B, Bartolomei F, Kobayashi K, Cimbalnik J, van ’t Klooster MA, Rampp S, et al. High-frequency oscillations: The state of clinical research. Epilepsia. 2017 Aug;58(8):1316–29.
- Frauscher B, von Ellenrieder N, Dubeau F, Gotman J. Different seizure-onset patterns in mesiotemporal lobe epilepsy have a distinct interictal signature. Clin Neurophysiol. 2017 Jul;128(7):1282–9.
- von Ellenrieder N, Dubeau F, Gotman J, Frauscher B. Physiological and pathological high-frequency oscillations have distinct sleep-homeostatic properties. Neuroimage Clin. 2017;14:566–73.
- Mooij AH, Frauscher B, Amiri M, Otte WM, Gotman J. Differentiating epileptic from non-epileptic high frequency intracerebral EEG signals with measures of wavelet entropy. Clin Neurophysiol. 2016 Dec;127(12):3529–36.
- Ferri R, Fulda S, Allen RP, Zucconi M, Bruni O, Chokroverty S, et al. World Association of Sleep Medicine (WASM) 2016 standards for recording and scoring leg movements in polysomnograms developed by a joint task force from the International and the European Restless Legs Syndrome Study Groups (IRLSSG and EURLSSG). Sleep Med. 2016 Oct;26:86–95.
- von Ellenrieder N, Dan J, Frauscher B, Gotman J. Sparse asynchronous cortical generators can produce measurable scalp EEG signals. Neuroimage. 2016 Sep;138:123–33.
- Amiri M, Frauscher B, Gotman J. Phase-amplitude coupling is elevated in deep sleep and in the onset zone of focal epileptic seizures. Frontiers in Human Neuroscience. 2016 Aug 3;10:12.
- Delazer M, Zamarian L, Frauscher B, Mitterling T, Stefani A, Heidbreder A, et al. Oxygen desaturation during night sleep affects decision-making in patients with obstructive sleep apnea. J Sleep Res. 2016 Aug;25(4):395–403.
- Gan-Or Z, Mohsin N, Girard SL, Montplaisir JY, Ambalavanan A, Strong S, et al. The role of the melanoma gene MC1R in Parkinson disease and REM sleep behavior disorder. Neurobiol Aging. 2016 Jul;43:180.e7-180.e13.
- von Ellenrieder N, Frauscher B, Dubeau F, Gotman J. Interaction with slow waves during sleep improves discrimination of physiologic and pathologic high-frequency oscillations (80-500 Hz). Epilepsia. 2016 Jun;57(6):869–78.
- Frauscher B, von Ellenrieder N, Dubeau F, Gotman J. EEG desynchronization during phasic REM sleep suppresses interictal epileptic activity in humans. Epilepsia. 2016 Jun;57(6):879–88.
- Pizzo F, Frauscher B, Ferrari-Marinho T, Amiri M, Dubeau F, Gotman J. Detectability of Fast Ripples (>250 Hz) on the Scalp EEG: A Proof-of-Principle Study with Subdermal Electrodes. Brain Topogr. 2016 May;29(3):358–67.
- Heidbreder A, Frauscher B, Mitterling T, Boentert M, Schirmacher A, Hörtnagl P, et al. Not Only Sleepwalking But NREM Parasomnia Irrespective of the Type Is Associated with HLA DQB1*05:01. J Clin Sleep Med. 2016 Apr 15;12(4):565–70.
- Brayet P, Petit D, Frauscher B, Gagnon J-F, Gosselin N, Gagnon K, et al. Quantitative EEG of Rapid-Eye-Movement Sleep: A Marker of Amnestic Mild Cognitive Impairment. Clin EEG Neurosci. 2016 Apr;47(2):134–41.
- Burnos S, Frauscher B, Zelmann R, Haegelen C, Sarnthein J, Gotman J. The morphology of high frequency oscillations (HFO) does not improve delineating the epileptogenic zone. Clin Neurophysiol. 2016 Apr;127(4):2140–8.
- Pizzo F, Ferrari-Marinho T, Amiri M, Frauscher B, Dubeau F, Gotman J. When spikes are symmetric, ripples are not: Bilateral spike and wave above 80 Hz in focal and generalized epilepsy. Clin Neurophysiol. 2016 Mar;127(3):1794–802.
- van Klink N, Frauscher B, Zijlmans M, Gotman J. Relationships between interictal epileptic spikes and ripples in surface EEG. Clin Neurophysiol. 2016 Jan;127(1):143–9.
- Frauscher B, Bernasconi N, Caldairou B, von Ellenrieder N, Bernasconi A, Gotman J, et al. Interictal Hippocampal Spiking Influences the Occurrence of Hippocampal Sleep Spindles. Sleep. 2015 Dec 1;38(12):1927–33.
- Sprenger FS, Stefanova N, Gelpi E, Seppi K, Navarro-Otano J, Offner F, et al. Enteric nervous system α-synuclein immunoreactivity in idiopathic REM sleep behavior disorder. Neurology. 2015 Nov 17;85(20):1761–8.
- Stefani A, Gabelia D, Högl B, Mitterling T, Mahlknecht P, Stockner H, et al. Long-Term Follow-up Investigation of Isolated Rapid Eye Movement Sleep Without Atonia Without Rapid Eye Movement Sleep Behavior Disorder: A Pilot Study. J Clin Sleep Med. 2015 Nov 15;11(11):1273–9.
- Stefani A, Gabelia D, Mitterling T, Poewe W, Högl B, Frauscher B. A Prospective Video-Polysomnographic Analysis of Movements during Physiological Sleep in 100 Healthy Sleepers. Sleep. 2015 Sep 1;38(9):1479–87.
- Mahlknecht P, Seppi K, Frauscher B, Kiechl S, Willeit J, Stockner H, et al. Probable RBD and association with neurodegenerative disease markers: A population-based study. Mov Disord. 2015 Sep;30(10):1417–21.
- Zamarian L, Högl B, Delazer M, Hingerl K, Gabelia D, Mitterling T, et al. Authors response to "Deficits of attention and cognition in narcoleptic patients--is it hypocretin dependent?". Sleep Med. 2015 Aug;16(8):1025.
- Menezes Cordeiro I, von Ellenrieder N, Zazubovits N, Dubeau F, Gotman J, Frauscher B. Sleep influences the intracerebral EEG pattern of focal cortical dysplasia. Epilepsy Res. 2015 Jul;113:132–9.
- Gan-Or Z, Girard SL, Noreau A, Leblond CS, Gagnon JF, Arnulf I, et al. Parkinson's Disease Genetic Loci in Rapid Eye Movement Sleep Behavior Disorder. J Mol Neurosci. 2015 Jul;56(3):617–22.
- Frauscher B, von Ellenrieder N, Ferrari-Marinho T, Avoli M, Dubeau F, Gotman J. Facilitation of epileptic activity during sleep is mediated by high amplitude slow waves. Brain. 2015 Jun;138(Pt 6):1629–41.
- Mitterling T, Högl B, Schönwald SV, Hackner H, Gabelia D, Biermayr M, et al. Sleep and Respiration in 100 Healthy Caucasian Sleepers--A Polysomnographic Study According to American Academy of Sleep Medicine Standards. Sleep. 2015 Jun 1;38(6):867–75.
- Ollila HM, Ravel JM, Han F, Faraco J, Lin L, Zheng X, et al. Erratum: HLA-DPB1 and HLA class i confer risk of and protection from narcolepsy (American Journal of Human Genetics (2015) 96 (136-146)). American Journal of Human Genetics. 2015 May 7;96(5):852.
- Postuma RB, Iranzo A, Hogl B, Arnulf I, Ferini-Strambi L, Manni R, et al. Risk factors for neurodegeneration in idiopathic rapid eye movement sleep behavior disorder: a multicenter study. Ann Neurol. 2015 May;77(5):830–9.
- Valli K, Frauscher B, Peltomaa T, Gschliesser V, Revonsuo A, Högl B. Dreaming furiously? A sleep laboratory study on the dream content of people with Parkinson's disease and with or without rapid eye movement sleep behavior disorder. Sleep Med. 2015 Mar;16(3):419–27.
- Mahlknecht P, Iranzo A, Högl B, Frauscher B, Müller C, Santamaría J, et al. Olfactory dysfunction predicts early transition to a Lewy body disease in idiopathic RBD. Neurology. 2015 Feb 17;84(7):654–8.
- Unterberger I, Gabelia D, Prieschl M, Chea K, Hofer M, Högl B, et al. Sleep disorders and circadian rhythm in epilepsy revisited: a prospective controlled study. Sleep Med. 2015 Feb;16(2):237–42.
- Spielberger S, Högl B, Mitterling T, Frauscher B, Löscher WN. Pain perception in narcolepsy with cataplexy patients. Sleep medicine. 2015 Feb;16(2):310.
- Frauscher B, von Ellenrieder N, Dubeau F, Gotman J. Scalp spindles are associated with widespread intracranial activity with unexpectedly low synchrony. Neuroimage. 2015 Jan 15;105:1–12.
- Ollila HM, Ravel J-M, Han F, Faraco J, Lin L, Zheng X, et al. HLA-DPB1 and HLA class I confer risk of and protection from narcolepsy. Am J Hum Genet. 2015 Jan 8;96(1):136–46.
- Stiasny-Kolster K, Sixel-Döring F, Trenkwalder C, Heinzel-Gutenbrunner M, Seppi K, Poewe W, et al. Diagnostic value of the REM sleep behavior disorder screening questionnaire in Parkinson's disease. Sleep Med. 2015 Jan;16(1):186–9.
- Ferini-Strambi L, Oertel W, Dauvilliers Y, Postuma RB, Marelli S, Iranzo A, et al. Erratum to: Autonomic symptoms in idiopathic REM behavior disorder: a multicentre case–control study (J Neurol, (2014), 261, (1112-1118), 10.1007/s00415-014-7317-8). Journal of Neurology. 2015 Jan 1;262(1):249–50.
- Zamarian L, Högl B, Delazer M, Hingerl K, Gabelia D, Mitterling T, et al. Subjective deficits of attention, cognition and depression in patients with narcolepsy. Sleep Med. 2015 Jan;16(1):45–51.
- Frauscher B, Högl B. Quality control for diagnosis of REM sleep behavior disorder: Criteria, questionnaires, video, and polysomnography. In: Disorders of Sleep and Circadian Rhythms in Parkinson’s Disease. 2015. p. 145–57.
- Walters AS, Frauscher B, Allen R, Benes H, Chaudhuri KR, Garcia-Borreguero D, et al. Review of diagnostic instruments for the restless legs syndrome/Willis-Ekbom Disease (RLS/WED): critique and recommendations. J Clin Sleep Med. 2014 Dec 15;10(12):1343–9.
- Walters AS, Frauscher B, Allen R, Benes H, Chaudhuri KR, Garcia-Borreguero D, et al. Review of quality of life instruments for the restless legs syndrome/Willis-Ekbom Disease (RLS/WED): critique and recommendations. J Clin Sleep Med. 2014 Dec 15;10(12):1351–7.
- Iranzo A, Stockner H, Serradell M, Seppi K, Valldeoriola F, Frauscher B, et al. Five-year follow-up of substantia nigra echogenicity in idiopathic REM sleep behavior disorder. Mov Disord. 2014 Dec;29(14):1774–80.
- Walters AS, Frauscher B, Allen R, Benes H, Chaudhuri KR, Garcia-Borreguero D, et al. Review of Severity Rating Scales for Restless Legs Syndrome: Critique and Recommendations. Movement Disorders Clinical Practice. 2014 Dec 1;1(4):317–24.
- Daoud H, Postuma RB, Bourassa CV, Rochefort D, Gauthier MT, Montplaisir J, et al. C9orf72 repeat expansions in rapid eye movement sleep behaviour disorder. Can J Neurol Sci. 2014 Nov;41(6):759–62.
- Mitterling T, Frauscher B, Falkenstetter T, Gschliesser V, Ehrmann L, Gabelia D, et al. Is there a polysomnographic signature of augmentation in restless legs syndrome? Sleep medicine. 2014 Oct;15(10):1231–40.
- Frauscher B, Gabelia D, Biermayr M, Stefani A, Hackner H, Mitterling T, et al. Validation of an integrated software for the detection of rapid eye movement sleep behavior disorder. Sleep. 2014 Oct 1;37(10):1663–71.
- Gabelia D, Mitterling T, Högl B, Wenning GK, Frauscher B. Do periodic arm movements during sleep exist in healthy subjects? A polysomnographic study. Sleep Med. 2014 Sep;15(9):1150–4.
- Sasai-Sakuma T, Frauscher B, Mitterling T, Ehrmann L, Gabelia D, Brandauer E, et al. Quantitative assessment of isolated rapid eye movement (REM) sleep without atonia without clinical REM sleep behavior disorder: clinical and research implications. Sleep Med. 2014 Sep;15(9):1009–15.
- Schulte EC, Kousi M, Tan PL, Tilch E, Knauf F, Lichtner P, et al. Targeted resequencing and systematic in vivo functional testing identifies rare variants in MEIS1 as significant contributors to restless legs syndrome. Am J Hum Genet. 2014 Jul 3;95(1):85–95.
- Frauscher B, Mitterling T, Bode A, Ehrmann L, Gabelia D, Biermayr M, et al. A prospective questionnaire study in 100 healthy sleepers: non-bothersome forms of recognizable sleep disorders are still present. J Clin Sleep Med. 2014 Jun 15;10(6):623–9.
- Ferini-Strambi L, Oertel W, Dauvilliers Y, Postuma RB, Marelli S, Iranzo A, et al. Autonomic symptoms in idiopathic REM behavior disorder: a multicentre case-control study. J Neurol. 2014 Jun;261(6):1112–8.
- Frauscher B, Gabelia D, Mitterling T, Biermayr M, Bregler D, Ehrmann L, et al. Motor events during healthy sleep: a quantitative polysomnographic study. Sleep. 2014 Apr 1;37(4):763-773B.
- Frauscher B, Jennum P, Ju Y-ES, Postuma RB, Arnulf I, Cochen De Cock V, et al. Comorbidity and medication in REM sleep behavior disorder: a multicenter case-control study. Neurology. 2014 Mar 25;82(12):1076–9.
- Schenck CH, Montplaisir JY, Frauscher B, Hogl B, Gagnon JF, Postuma R, et al. Corrigendum to "Rapid eye movement sleep behavior disorder: Devising controlled active treatment studies for symptomatic and neuroprotective therapy-a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group" [Sleep Med 14(8) (2013) 795-806]. Sleep Medicine. 2014 Jan 1;15(1):157.
- Tafti M, Hor H, Dauvilliers Y, Lammers GJ, Overeem S, Mayer G, et al. DQB1 locus alone explains most of the risk and protection in narcolepsy with cataplexy in Europe. Sleep. 2014 Jan 1;37(1):19–25.
- Schulte EC, Schramm K, Schurmann C, Lichtner P, Herder C, Roden M, et al. Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome. PloS one. 2014 Jan;9(5):e98092.
- Walters AS, Gabelia D, Frauscher B. Restless legs syndrome (Willis-Ekbom disease) and growing pains: are they the same thing? A side-by-side comparison of the diagnostic criteria for both and recommendations for future research. Sleep Med. 2013 Dec;14(12):1247–52.
- Maurovich-Horvat E, Kemlink D, Högl B, Frauscher B, Ehrmann L, Geisler P, et al. Narcolepsy and pregnancy: a retrospective European evaluation of 249 pregnancies. J Sleep Res. 2013 Oct;22(5):496–512.
- Frauscher B, Ehrmann L, Mitterling T, Gabelia D, Gschliesser V, Brandauer E, et al. Delayed diagnosis, range of severity, and multiple sleep comorbidities: a clinical and polysomnographic analysis of 100 patients of the innsbruck narcolepsy cohort. J Clin Sleep Med. 2013 Aug 15;9(8):805–12.
- Schenck CH, Montplaisir JY, Frauscher B, Hogl B, Gagnon J-F, Postuma R, et al. Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy--a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group. Sleep Med. 2013 Aug;14(8):795–806.
- Frauscher B, Ehrmann L, Högl B. Defining muscle activities for assessment of rapid eye movement sleep behavior disorder: from a qualitative to a quantitative diagnostic level. Sleep Med. 2013 Aug;14(8):729–33.
- Dauvilliers Y, Postuma RB, Ferini-Strambi L, Arnulf I, Högl B, Manni R, et al. Family history of idiopathic REM behavior disorder: a multicenter case-control study. Neurology. 2013 Jun 11;80(24):2233–5.
- Mitterling T, Frauscher B, Ehrmann L, Gschliesser V, Brandauer E, Högl B. Is a diagnosis of ancillary restless legs syndrome reproducible over time? Experience with the Wayne Hening telephone diagnostic interview. Sleep medicine. 2013 Jun;14(6):572–4.
- Oexle K, Schormair B, Ried JS, Czamara D, Heim K, Frauscher B, et al. Dilution of candidates: the case of iron-related genes in restless legs syndrome. European journal of human genetics : EJHG. 2013 Apr;21(4):410–4.
- Ferri R, Gschliesser V, Frauscher B, Poewe W, Hogl B. On “polysomnography reveals unexpectedly high rates of organic sleep disorders in patients with prediagnosed primary insomnia” (Sleep Breath 2011 doi 10.1007/s11325-011-0608-8). Sleep & breathing = Schlaf & Atmung. 2013 Mar;17(1):1–2.
- Faraco J, Lin L, Kornum BR, Kenny EE, Trynka G, Einen M, et al. ImmunoChip study implicates antigen presentation to T cells in narcolepsy. PLoS Genet. 2013;9(2):e1003270.
- Frauscher B, Ehrmann L, Zamarian L, Auer F, Mitterling T, Gabelia D, et al. Validation of the Innsbruck REM sleep behavior disorder inventory. Mov Disord. 2012 Nov;27(13):1673–8.
- Frauscher B, Löscher WN, Ehrmann L, Gschliesser V, Brandauer E, Högl B, et al. Narcolepsy-cataplexy: deficient prepulse inhibition of blink reflex suggests pedunculopontine involvement. J Sleep Res. 2012 Oct;21(5):495–501.
- Postuma RB, Montplaisir JY, Pelletier A, Dauvilliers Y, Oertel W, Iranzo A, et al. Environmental risk factors for REM sleep behavior disorder: A multicenter case-control study. Neurology. 2012 Jul 31;79(5):428–34.
- Frauscher B, Iranzo A, Gaig C, Gschliesser V, Guaita M, Raffelseder V, et al. Normative EMG values during REM sleep for the diagnosis of REM sleep behavior disorder. Sleep. 2012 Jun 1;35(6):835–47.
- Postuma RB, Arnulf I, Hogl B, Iranzo A, Miyamoto T, Dauvilliers Y, et al. A single-question screen for rapid eye movement sleep behavior disorder: a multicenter validation study. Mov Disord. 2012 Jun;27(7):913–6.
- Frauscher B, Nomura T, Duerr S, Ehrmann L, Gschliesser V, Wenning GK, et al. Investigation of autonomic function in idiopathic REM sleep behavior disorder. J Neurol. 2012 Jun;259(6):1056–61.
- Delazer M, Högl B, Zamarian L, Wenter J, Ehrmann L, Gschliesser V, et al. Decision making and executive functions in REM sleep behavior disorder. Sleep. 2012 May 1;35(5):667–73.
- Scherfler C, Frauscher B, Schocke M, Nocker M, Gschliesser V, Ehrmann L, et al. White and gray matter abnormalities in narcolepsy with cataplexy. Sleep. 2012 Mar 1;35(3):345–51.
- Valli K, Frauscher B, Gschliesser V, Wolf E, Falkenstetter T, Schönwald SV, et al. Can observers link dream content to behaviours in rapid eye movement sleep behaviour disorder? A cross-sectional experimental pilot study. J Sleep Res. 2012 Feb;21(1):21–9.
- Frauscher B, Comella CL. Sleep-related movement disorders. In: Movement Disorders in Neurologic and Systemic Disease. 2012. p. 314–32.
- Kuchukhidze G, Toidze I, Khatiashvili I, Maisuradze L, Frauscher B, Kasradze S, et al. Prevalence of restless legs syndrome in a Georgian primary healthcare setting: a pilot study. Eur Neurol. 2012;68(3):177–80.
- King J, Kupferthaler A, Frauscher B, Hackner H, Unterkofler K, Teschl G, et al. Measurement of endogenous acetone and isoprene in exhaled breath during sleep. Physiological Measurement. 2012 Jan 1;33(3):413–28.
- Frauscher B, Gschliesser V, Brandauer E, Schönwald SV, Falkenstetter T, Ehrmann L, et al. Motor disturbances during non-REM and REM sleep in narcolepsy-cataplexy: a video-polysomnographic analysis. J Sleep Res. 2011 Dec;20(4):514–21.
- Kornum BR, Kawashima M, Faraco J, Lin L, Rico TJ, Hesselson S, et al. Erratum: Common variants in P2RY11 are associated with narcolepsy (Nature Genetics (2011) 43 (66-71)). Nature Genetics. 2011 Oct 1;43(10):1040.
- Winkelmann J, Czamara D, Schormair B, Knauf F, Schulte EC, Trenkwalder C, et al. Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1. PLoS Genet. 2011 Jul;7(7):e1002171.
- Delazer M, Högl B, Zamarian L, Wenter J, Gschliesser V, Ehrmann L, et al. Executive functions, information sampling, and decision making in narcolepsy with cataplexy. Neuropsychology. 2011 Jul;25(4):477–87.
- Frauscher B, Kunz A, Brandauer E, Ulmer H, Poewe W, Högl B. Fragmentary myoclonus in sleep revisited: a polysomnographic study in 62 patients. Sleep Med. 2011 Apr;12(4):410–5.
- Trenkwalder C, Kohnen R, Högl B, Metta V, Sixel-Döring F, Frauscher B, et al. Parkinson's disease sleep scale--validation of the revised version PDSS-2. Mov Disord. 2011 Mar;26(4):644–52.
- Iranzo A, Frauscher B, Santos H, Gschliesser V, Ratti L, Falkenstetter T, et al. Usefulness of the SINBAR electromyographic montage to detect the motor and vocal manifestations occurring in REM sleep behavior disorder. Sleep Med. 2011 Mar;12(3):284–8.
- Scherfler C, Frauscher B, Schocke M, Iranzo A, Gschliesser V, Seppi K, et al. White and gray matter abnormalities in idiopathic rapid eye movement sleep behavior disorder: a diffusion-tensor imaging and voxel-based morphometry study. Ann Neurol. 2011 Feb;69(2):400–7.
- Frauscher B, Hering S, Högl B, Gschliesser V, Ulmer H, Poewe W, et al. Restless legs syndrome in Friedreich ataxia: a polysomnographic study. Mov Disord. 2011 Feb 1;26(2):302–6.
- Kornum BR, Kawashima M, Faraco J, Lin L, Rico TJ, Hesselson S, et al. Common variants in P2RY11 are associated with narcolepsy. Nat Genet. 2011 Jan;43(1):66–71.
- Frauscher B, Brandauer E, Gschliesser V, Falkenstetter T, Furtner MT, Ulmer H, et al. A descriptive analysis of neck myoclonus during routine polysomnography. Sleep. 2010 Aug;33(8):1091–6.
- Frauscher B, Seppi K, Högl B, Poewe W. Reply: "Restless legs syndrome and Parkinson's disease". Movement Disorders. 2010 Jul 15;25(9):1314–5.
- Högl B, Frauscher B, Sergio Podestá C. Restless Legs Syndrome. In: International Neurology: A Clinical Approach. 2010. p. 566–8.
- Falkenstetter T, Frauscher B, Anderer P, Bolitschek J, Fugger B, Holzinger B, et al. Excessive daytime sleepiness in Austria: Prevalence and risk factors. Somnologie. 2010 Mar 1;14(1):15–22.
- Högl B, García-Borreguero D, Kohnen R, Ferini-Strambi L, Hadjigeorgiou G, Hornyak M, et al. Progressive development of augmentation during long-term treatment with levodopa in restless legs syndrome: results of a prospective multi-center study. J Neurol. 2010 Feb;257(2):230–7.
- Frauscher B, Gschliesser V, Brandauer E, Marti I, Furtner MT, Ulmer H, et al. REM sleep behavior disorder in 703 sleep-disorder patients: the importance of eliciting a comprehensive sleep history. Sleep Med. 2010 Feb;11(2):167–71.
- Peralta CM, Frauscher B, Seppi K, Wolf E, Wenning GK, Högl B, et al. Restless legs syndrome in Parkinson's disease. Mov Disord. 2009 Oct 30;24(14):2076–80.
- Stockner H, Iranzo A, Seppi K, Serradell M, Gschliesser V, Sojer M, et al. Midbrain hyperechogenicity in idiopathic REM sleep behavior disorder. Mov Disord. 2009 Oct 15;24(13):1906–9.
- Furtner M, Staudacher M, Frauscher B, Brandauer E, Esnaola y Rojas MM, Gschliesser V, et al. Cerebral vasoreactivity decreases overnight in severe obstructive sleep apnea syndrome: a study of cerebral hemodynamics. Sleep Med. 2009 Sep;10(8):875–81.
- Hallmayer J, Faraco J, Lin L, Hesselson S, Winkelmann J, Kawashima M, et al. Erratum: Narcolepsy is strongly associated with the T-cell receptor alpha locus (Nature Genetics (2009) 41 (708-711)). Nature Genetics. 2009 Jul 1;41(7):859.
- Hallmayer J, Faraco J, Lin L, Hesselson S, Winkelmann J, Kawashima M, et al. Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet. 2009 Jun;41(6):708–11.
- Frauscher B, Gschliesser V, Brandauer E, El-Demerdash E, Kaneider M, Rücker L, et al. The severity range of restless legs syndrome (RLS) and augmentation in a prospective patient cohort: association with ferritin levels. Sleep Med. 2009 Jun;10(6):611–5.
- Gschliesser V, Högl B, Frauscher B, Brandauer E, Poewe W, Luef G. Mode of vagus nerve stimulation differentially affects sleep related breathing in patients with epilepsy. Seizure. 2009 Jun;18(5):339–42.
- Kemlink D, Polo O, Frauscher B, Gschliesser V, Högl B, Poewe W, et al. Replication of restless legs syndrome loci in three European populations. J Med Genet. 2009 May;46(5):315–8.
- Gschliesser V, Frauscher B, Brandauer E, Kohnen R, Ulmer H, Poewe W, et al. PLM detection by actigraphy compared to polysomnography: a validation and comparison of two actigraphs. Sleep Med. 2009 Mar;10(3):306–11.
- Frauscher B, Gschliesser V, Brandauer E, Ulmer H, Poewe W, Högl B. The relation between abnormal behaviors and REM sleep microstructure in patients with REM sleep behavior disorder. Sleep Med. 2009 Feb;10(2):174–81.
- Ferri R, Gschliesser V, Frauscher B, Poewe W, Högl B. Periodic leg movements during sleep and periodic limb movement disorder in patients presenting with unexplained insomnia. Clin Neurophysiol. 2009 Feb;120(2):257–63.
- Schormair B, Kemlink D, Roeske D, Eckstein G, Xiong L, Lichtner P, et al. PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome. Nat Genet. 2008 Aug;40(8):946–8.
- Kemlink D, Plazzi G, Vetrugno R, Provini F, Polo O, Stiasny-Kolster K, et al. Suggestive evidence for linkage for restless legs syndrome on chromosome 19p13. Neurogenetics. 2008 May;9(2):75–82.
- Frauscher B, Iranzo A, Högl B, Casanova-Molla J, Salamero M, Gschliesser V, et al. Quantification of electromyographic activity during REM sleep in multiple muscles in REM sleep behavior disorder. Sleep. 2008 May;31(5):724–31.
- García-Borreguero D, Kohnen R, Högl B, Ferini-Strambi L, Hadjigeorgiou GM, Hornyak M, et al. Validation of the Augmentation Severity Rating Scale (ASRS): a multicentric, prospective study with levodopa on restless legs syndrome. Sleep Med. 2007 Aug;8(5):455–63.
- Frauscher B, Gschliesser V, Brandauer E, Ulmer H, Peralta CM, Müller J, et al. Video analysis of motor events in REM sleep behavior disorder. Mov Disord. 2007 Jul 30;22(10):1464–70.
- Frauscher B, Löscher W, Högl B, Poewe W, Kofler M. Erratum: Auditory startle reaction is disinhibited in idiopathic restless legs syndrome (Sleep (2007) 30, 4, (489-493)). Sleep. 2007 May 1;30(5):547.
- Frauscher B, Löscher W, Högl B, Poewe W, Kofler M. Auditory startle reaction is disinhibited in idiopathic restless legs syndrome. Sleep. 2007 Apr;30(4):489–93.
- Kemlink D, Polo O, Montagna P, Provini F, Stiasny-Kolster K, Oertel W, et al. Family-based association study of the restless legs syndrome loci 2 and 3 in a European population. Mov Disord. 2007 Jan 15;22(2):207–12.
- Boesch SM, Frauscher B, Brandauer E, Wenning GK, Högl B, Poewe W. Disturbance of rapid eye movement sleep in spinocerebellar ataxia type 2. Mov Disord. 2006 Oct;21(10):1751–4.
- Frauscher B, Högl B. The role of laboratory diagnostics in sleep medicine. LaboratoriumsMedizin. 2006 Oct 1;30(5):289–95.
- Boesch SM, Frauscher B, Brandauer E, Wenning GK, Poewe W, Högl B. Restless legs syndrome and motor activity during sleep in spinocerebellar ataxia type 6. Sleep Med. 2006 Sep;7(6):529–32.
- Rissling I, Frauscher B, Kronenberg F, Tafti M, Stiasny-Kolster K, Robyr A-C, et al. Daytime sleepiness and the COMT val158met polymorphism in patients with Parkinson disease. Sleep. 2006 Jan;29(1):108–11.
- Brenneis C, Brandauer E, Frauscher B, Schocke M, Trieb T, Poewe W, et al. Voxel-based morphometry in narcolepsy. Sleep Med. 2005 Nov;6(6):531–6.
- Frauscher B, Egg R, Brandauer E, Ulmer H, Berger T, Poewe W, et al. Daytime sleepiness is not increased in mild to moderate multiple sclerosis: a pupillographic study. Sleep medicine. 2005 Nov;6(6):543–7.
- Högl B, Kiechl S, Willeit J, Saletu M, Frauscher B, Seppi K, et al. Restless legs syndrome: a community-based study of prevalence, severity, and risk factors. Neurology. 2005 Jun 14;64(11):1920–4.
- Frauscher B, Högl B, Maret S, Wolf E, Brandauer E, Wenning GK, et al. Association of daytime sleepiness with COMT polymorphism in patients with parkinson disease: a pilot study. Sleep. 2004 Jun;27(4):733–6.
- Högl B, Seppi K, Brandauer E, Glatzl S, Frauscher B, Niedermüller U, et al. Increased daytime sleepiness in Parkinson's disease: a questionnaire survey. Movement disorders : official journal of the Movement Disorder Society. 2003 Mar;18(3):319–23.
- Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisi J, et al. Restless legs syndrome: Diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Medicine. 2003 Jan 1;4(2):101–19.
- Högl B, Frauscher B, Seppi K, Ulmer H, Poewe W. Transient restless legs syndrome after spinal anesthesia: a prospective study. Neurology. 2002 Dec 10;59(11):1705–7.
- Högl B, Saletu M, Brandauer E, Glatzl S, Frauscher B, Seppi K, et al. Modafinil for the treatment of daytime sleepiness in Parkinson's disease: a double-blind, randomized, crossover, placebo-controlled polygraphic trial. Sleep. 2002 Dec;25(8):905–9.