Birgit Frauscher
Neurology, Epilepsy and Sleep
Professor of Neurology
Bio
Dr. Birgit Frauscher is a clinician scientist whose career is dedicated to improve diagnosis and prognosis of people with epilepsy by developing new methods based on advanced electroencephalography techniques to better localize the epileptic focus in order to improve epilepsy treatment outcomes and ultimately achieve the best possible quality of life. She is currently holding the position of Director of the Duke Comprehensive Epilepsy Center and holds a secondary appointment with the Department of Biomedical Engineering at the Duke Pratt School of Engineering.
Her academic journey started at the Medical University of Innsbruck in Austria, where she accomplished her medical training, residency in neurology, and subspecialty training in electroencephalography, epilepsy and sleep medicine. Early in her career during Medical School she became fascinated by the technique of electroencephalography and how it allows to draw important conclusions on brain function. After completion of her clinical training in 2008, she underwent subsequent research training resulting in the successful completion of her habilitation degree in 2011. To specialize on intracranial EEG and signal analysis, she spent a visiting professorship at the Montreal Neurological Institute and Hospital, McGill University in Canada between 2013 – 2015. Subsequently, she served at the Montreal Neurological Institute and Hospital as an Attending Epileptologist and later as Group Leader of Epilepsy and Professor of Neurology.
Her research interests include i) the development of novel seizure-independent EEG markers for the epileptogenic zone in order to achieve a more accurate diagnosis of epilepsy, ii) the investigation of the important interactions between sleep and epilepsy, and iii) the use of the unique possibility of invasive intracranial EEG for studying brain physiology during wakefulness and sleep in order to better delineate normal from abnormal intracranial EEG activity.
Dr. Frauscher’s publication record holds over 170 peer-reviewed papers dedicated to epilepsy and sleep with a H-index of 62. Her scholarly endeavors have earned her several prestigious awards, including Clinician-Scientist awards of the FRSQ (2018-2023), the Michael Prize of the International League against Epilepsy (2019) and the Ernst Niedermeyer Prize from the Austrian Epilepsy Society (2015). Dr. Frauscher's dedication to pushing the boundaries of epilepsy and sleep research highlights her standing in the field and her significant contributions to advancing clinical knowledge.
Education
- M.D. University of Innsbruck (Austria), 2001
Trainings & Certifications
- Neurology Residency Program (included a two-year fellowship in clinical neurophysiology, epilepsy, and sleep), Innsbruck Medi, NEUROLOGY (2002 - 2008) University of Innsbruck (Austria)
Positions
- Professor of Neurology
- Director of the Epilepsy Lab in the Department of Neurology
- Professor of Biomedical Engineering
Publications
- Thomas J, Abdallah C, Jaber K, Khweileh M, Aron O, Doležalová I, et al. Development of a stereo-EEG based seizure matching system for clinical decision making in epilepsy surgery. J Neural Eng. 2024 Oct 4;21(5).
- Azeem A, Abdallah C, von Ellenrieder N, El Kosseifi C, Frauscher B, Gotman J. Explaining slow seizure propagation with white matter tractography. Brain. 2024 Oct 3;147(10):3458–70.
- Latreille V, Corbin-Lapointe J, Peter-Derex L, Thomas J, Lina J-M, Frauscher B. Oscillatory and nonoscillatory sleep electroencephalographic biomarkers of the epileptic network. Epilepsia. 2024 Oct;65(10):3038–51.
- Klimes P, Nejedly P, Hrtonova V, Cimbalnik J, Travnicek V, Pail M, et al. Interictal stereo-electroencephalography features below 45 Hz are sufficient for correct localization of the epileptogenic zone and postsurgical outcome prediction. Epilepsia. 2024 Oct;65(10):2935–45.
- Mansilla D, Tveit J, Aurlien H, Avigdor T, Ros-Castello V, Ho A, et al. Generalizability of electroencephalographic interpretation using artificial intelligence: An external validation study. Epilepsia. 2024 Oct;65(10):3028–37.
- Wadi L, Khweileh M, Agashe S, Southwell D, Parikh P, Frauscher B. Sleep-related hypermotor seizures originating from the occipital lobe. Epileptic Disord. 2024 Sep 21;
- Wei X, Avigdor T, Ho A, Minato E, Garcia-Asensi A, Royer J, et al. ANPHY-Sleep: an Open Sleep Database from Healthy Adults Using High-Density Scalp Electroencephalogram. Sci Data. 2024 Aug 17;11(1):896.
- Ngo A, Royer J, Rodriguez-Cruces R, Xie K, DeKraker J, Auer H, et al. Associations of Cerebral Blood Flow Patterns With Gray and White Matter Structure in Patients With Temporal Lobe Epilepsy. Neurology. 2024 Aug 13;103(3):e209528.
- Thomas J, Abdallah C, Cai Z, Jaber K, Gotman J, Beniczky S, et al. Investigating current clinical opinions in stereoelectroencephalography-informed epilepsy surgery. Epilepsia. 2024 Aug 3;
- Schiller K, Thomas J, Avigdor T, Mansilla D, Kortas A, Unterholzner G, et al. Pulsatile corticoid therapy reduces interictal epileptic activity burden in children with genetic drug-resistant epilepsy. Epilepsia Open. 2024 Aug;9(4):1265–76.
- Afnan J, Cai Z, Lina J-M, Abdallah C, Delaire E, Avigdor T, et al. EEG/MEG source imaging of deep brain activity within the maximum entropy on the mean framework: Simulations and validation in epilepsy. Hum Brain Mapp. 2024 Jul 15;45(10):e26720.
- Larivière S, Park B-Y, Royer J, DeKraker J, Ngo A, Sahlas E, et al. Connectome reorganization associated with temporal lobe pathology and its surgical resection. Brain. 2024 Jul 5;147(7):2483–95.
- Shi W, Shaw D, Walsh KG, Han X, Eden UT, Richardson RM, et al. Spike ripples localize the epileptogenic zone best: an international intracranial study. Brain. 2024 Jul 5;147(7):2496–506.
- Abdallah C, Mansilla D, Minato E, Grova C, Beniczky S, Frauscher B. Systematic review of seizure-onset patterns in stereo-electroencephalography: Current state and future directions. Clin Neurophysiol. 2024 Jul;163:112–23.
- Kalamangalam G, Frauscher B. The SEEG Wave. J Clin Neurophysiol. 2024 Jul 1;41(5):397–8.
- Hannan S, Ho A, Frauscher B. Clinical Utility of Sleep Recordings During Presurgical Epilepsy Evaluation With Stereo-Electroencephalography: A Systematic Review. J Clin Neurophysiol. 2024 Jul 1;41(5):430–43.
- Jaber K, Avigdor T, Mansilla D, Ho A, Thomas J, Abdallah C, et al. A spatial perturbation framework to validate implantation of the epileptogenic zone. Nat Commun. 2024 Jun 19;15(1):5253.
- Tavakol S, Kebets V, Royer J, Li Q, Auer H, DeKraker J, et al. Differential relational memory impairment in temporal lobe epilepsy. Epilepsy Behav. 2024 Jun;155:109722.
- Ryvlin P, Barba C, Bartolomei F, Baumgartner C, Brazdil M, Fabo D, et al. Grading system for assessing the confidence in the epileptogenic zone reported in published studies: A Delphi consensus study. Epilepsia. 2024 May;65(5):1346–59.
- Chybowski B, Klimes P, Cimbalnik J, Travnicek V, Nejedly P, Pail M, et al. Timing matters for accurate identification of the epileptogenic zone. Clin Neurophysiol. 2024 May;161:1–9.
- Xie K, Royer J, Larivière S, Rodriguez-Cruces R, Frässle S, Cabalo DG, et al. Atypical connectome topography and signal flow in temporal lobe epilepsy. Prog Neurobiol. 2024 May;236:102604.
- Wang YL, Avigdor T, Hannan S, Abdallah C, Dubeau F, Peter-Derex L, et al. Intracerebral Dynamics of Sleep Arousals: A Combined Scalp-Intracranial EEG Study. J Neurosci. 2024 Apr 17;44(16).
- Frauscher B, Rossetti AO, Beniczky S. Recent advances in clinical electroencephalography. Curr Opin Neurol. 2024 Apr 1;37(2):134–40.
- Latreille V, Avigdor T, Thomas J, Crane J, Sziklas V, Jones-Gotman M, et al. Scalp and hippocampal sleep correlates of memory function in drug-resistant temporal lobe epilepsy. Sleep. 2024 Feb 8;47(2).
- Frauscher B, Mansilla D, Abdallah C, Astner-Rohracher A, Beniczky S, Brazdil M, et al. Learn how to interpret and use intracranial EEG findings. Epileptic Disord. 2024 Feb;26(1):1–59.
- Avigdor T, Abdallah C, Afnan J, Cai Z, Rammal S, Grova C, et al. Consistency of electrical source imaging in presurgical evaluation of epilepsy across different vigilance states. Ann Clin Transl Neurol. 2024 Feb;11(2):389–403.
- Bernard C, Frauscher B, Gelinas J, Timofeev I. Sleep, oscillations, and epilepsy. Epilepsia. 2023 Dec;64 Suppl 3(Suppl 3):S3–12.
- Horrillo-Maysonnial A, Avigdor T, Abdallah C, Mansilla D, Thomas J, von Ellenrieder N, et al. Targeted density electrode placement achieves high concordance with traditional high-density EEG for electrical source imaging in epilepsy. Clin Neurophysiol. 2023 Dec;156:262–71.
- Frauscher B, Bartolomei F, Baud MO, Smith RJ, Worrell G, Lundstrom BN. Stimulation to probe, excite, and inhibit the epileptic brain. Epilepsia. 2023 Dec;64 Suppl 3(Suppl 3):S49–61.
- Ho A, Hannan S, Thomas J, Avigdor T, Abdallah C, Dubeau F, et al. Rapid eye movement sleep affects interictal epileptic activity differently in mesiotemporal and neocortical areas. Epilepsia. 2023 Nov;64(11):3036–48.
- Sklenarova B, Zatloukalova E, Cimbalnik J, Klimes P, Dolezalova I, Pail M, et al. Interictal high-frequency oscillations, spikes, and connectivity profiles: A fingerprint of epileptogenic brain pathologies. Epilepsia. 2023 Nov;64(11):3049–60.
- Hannan S, Thomas J, Jaber K, El Kosseifi C, Ho A, Abdallah C, et al. The Differing Effects of Sleep on Ictal and Interictal Network Dynamics in Drug-Resistant Epilepsy. Ann Neurol. 2023 Sep 15;
- Royer J, Larivière S, Rodriguez-Cruces R, Cabalo DG, Tavakol S, Auer H, et al. Cortical microstructural gradients capture memory network reorganization in temporal lobe epilepsy. Brain. 2023 Sep 1;146(9):3923–37.
- Ibrahim A, Ferri R, Cesari M, Frauscher B, Heidbreder A, Bergmann M, et al. Large muscle group movements during sleep in healthy people: normative values and correlation to sleep features. Sleep. 2023 Aug 14;46(8).
- Afnan J, von Ellenrieder N, Lina J-M, Pellegrino G, Arcara G, Cai Z, et al. Validating MEG source imaging of resting state oscillatory patterns with an intracranial EEG atlas. Neuroimage. 2023 Jul 1;274:120158.
- Peter-Derex L, von Ellenrieder N, van Rosmalen F, Hall J, Dubeau F, Gotman J, et al. Regional variability in intracerebral properties of NREM to REM sleep transitions in humans. Proc Natl Acad Sci U S A. 2023 Jun 27;120(26):e2300387120.
- Peter-Derex L, Avigdor T, Rheims S, Guénot M, von Ellenrieder N, Gotman J, et al. Enhanced thalamocortical functional connectivity during rapid-eye-movement sleep sawtooth waves. Sleep. 2023 Jun 13;46(6).
- Frauscher B, Bénar CG, Engel JJ, Grova C, Jacobs J, Kahane P, et al. Neurophysiology, Neuropsychology, and Epilepsy, in 2022: Hills We Have Climbed and Hills Ahead. Neurophysiology in epilepsy. Epilepsy Behav. 2023 Jun;143:109221.
- Travnicek V, Klimes P, Cimbalnik J, Frauscher B. Response: Can biomarkers of the epileptogenic zone be characterized in patients rendered seizure free alone? Epilepsia. 2023 Jun;64(6):1695.
- Zelmann R, Frauscher B, Aro RP, Gueziri H-E, Collins DL. SEEGAtlas: A framework for the identification and classification of depth electrodes using clinical images. J Neural Eng. 2023 May 31;20(3).
- Travnicek V, Klimes P, Cimbalnik J, Halamek J, Jurak P, Brinkmann B, et al. Relative entropy is an easy-to-use invasive electroencephalographic biomarker of the epileptogenic zone. Epilepsia. 2023 Apr;64(4):962–72.
- Xie K, Royer J, Lariviere S, Rodriguez-Cruces R, de Wael RV, Park B-Y, et al. Atypical intrinsic neural timescales in temporal lobe epilepsy. Epilepsia. 2023 Apr;64(4):998–1011.
- Thomas J, Kahane P, Abdallah C, Avigdor T, Zweiphenning WJEM, Chabardes S, et al. A Subpopulation of Spikes Predicts Successful Epilepsy Surgery Outcome. Ann Neurol. 2023 Mar;93(3):522–35.
- Schiller K, von Ellenrieder N, Avigdor T, El Kosseifi C, Abdallah C, Minato E, et al. Focal epilepsy impacts rapid eye movement sleep microstructure. Sleep. 2023 Feb 8;46(2).
- Azeem A, von Ellenrieder N, Royer J, Frauscher B, Bernhardt B, Gotman J. Integration of white matter architecture to stereo-EEG better describes epileptic spike propagation. Clin Neurophysiol. 2023 Feb;146:135–46.
- Eckhardt C, Fanciulli A, Högl B, Heidbreder A, Eschlböck S, Raccagni C, et al. Analysis of sleep, daytime sleepiness, and autonomic function in multiple system atrophy and Parkinson disease: a prospective study. J Clin Sleep Med. 2023 Jan 1;19(1):63–71.
- Latreille V, Schiller K, Peter-Derex L, Frauscher B. Does epileptic activity impair sleep-related memory consolidation in epilepsy? A critical and systematic review. J Clin Sleep Med. 2022 Oct 1;18(10):2481–95.
- Royer J, Rodríguez-Cruces R, Tavakol S, Larivière S, Herholz P, Li Q, et al. An Open MRI Dataset For Multiscale Neuroscience. Sci Data. 2022 Sep 15;9(1):569.
- Dinkelacker V, El Helou J, Frauscher B. Interictal sleep recordings during presurgical evaluation: Bidirectional perspectives on sleep related network functioning. Rev Neurol (Paris). 2022 Sep;178(7):703–13.
- Nobili L, Frauscher B, Eriksson S, Gibbs SA, Halasz P, Lambert I, et al. Sleep and epilepsy: A snapshot of knowledge and future research lines. J Sleep Res. 2022 Aug;31(4):e13622.
- Schiller K, Avigdor T, Abdallah C, Sziklas V, Crane J, Stefani A, et al. Focal epilepsy disrupts spindle structure and function. Sci Rep. 2022 Jul 1;12(1):11137.
- Abdallah C, Hedrich T, Koupparis A, Afnan J, Hall JA, Gotman J, et al. Clinical Yield of Electromagnetic Source Imaging and Hemodynamic Responses in Epilepsy: Validation With Intracerebral Data. Neurology. 2022 Jun 13;98(24):e2499–511.
- von Ellenrieder N, Peter-Derex L, Gotman J, Frauscher B. SleepSEEG: automatic sleep scoring using intracranial EEG recordings only. J Neural Eng. 2022 May 3;19(2).
- Serlin Y, Alshahrani M, Frauscher B. Provocative Hyperventilation in a Patient With Stroke-Like Migraine Attacks After Radiation Therapy. JAMA neurology. 2022 May;79(5):526–7.
- Kokkinos V, Urban A, Frauscher B, Simon M, Hussein H, Bush A, et al. Barques are generated in posterior hippocampus and phase reverse over lateral posterior hippocampal surface. Clin Neurophysiol. 2022 Apr;136:150–7.
- Zhang H, Iranzo A, Högl B, Arnulf I, Ferini-Strambi L, Manni R, et al. Risk Factors for Phenoconversion in Rapid Eye Movement Sleep Behavior Disorder. Ann Neurol. 2022 Mar;91(3):404–16.
- Zweiphenning WJEM, von Ellenrieder N, Dubeau F, Martineau L, Minotti L, Hall JA, et al. Correcting for physiological ripples improves epileptic focus identification and outcome prediction. Epilepsia. 2022 Feb;63(2):483–96.
- Klimes P, Peter-Derex L, Hall J, Dubeau F, Frauscher B. Spatio-temporal spike dynamics predict surgical outcome in adult focal epilepsy. Clin Neurophysiol. 2022 Feb;134:88–99.
- Delgado-Garcia G, Frauscher B. Future of Neurology & Technology: Stereoelectroencephalography in Presurgical Epilepsy Evaluation. Neurology. 2022 Jan 24;98(4):e437–40.
- Olejarczyk E, Gotman J, Frauscher B. Region-specific complexity of the intracranial EEG in the sleeping human brain. Sci Rep. 2022 Jan 10;12(1):451.
- Astner-Rohracher A, Zimmermann G, Avigdor T, Abdallah C, Barot N, Brázdil M, et al. Development and Validation of the 5-SENSE Score to Predict Focality of the Seizure-Onset Zone as Assessed by Stereoelectroencephalography. JAMA Neurol. 2022 Jan 1;79(1):70–9.
- Dimakopoulos V, Gotman J, Stacey W, Von Ellenrieder N, Jacobs J, Papadelis C, et al. Protocol for multicentre comparison of interictal high-frequency oscillations as a predictor of seizure freedom. Brain Communications. 2022 Jan 1;4(3).
- Kokkinos V, Hussein H, Frauscher B, Simon M, Urban A, Bush A, et al. Hippocampal spindles and barques are normal intracranial electroencephalographic entities. Clin Neurophysiol. 2021 Dec;132(12):3002–9.
- de la Chapelle A, Frauscher B, Valomon A, Ruby PM, Peter-Derex L. Relationship Between Epilepsy and Dreaming: Current Knowledge, Hypotheses, and Perspectives. Frontiers in Neuroscience. 2021 Sep 6;15.
- Li Q, Tavakol S, Royer J, Larivière S, Vos De Wael R, Park B-Y, et al. Atypical neural topographies underpin dysfunctional pattern separation in temporal lobe epilepsy. Brain. 2021 Sep 4;144(8):2486–98.
- Azeem A, von Ellenrieder N, Hall J, Dubeau F, Frauscher B, Gotman J. Interictal spike networks predict surgical outcome in patients with drug-resistant focal epilepsy. Ann Clin Transl Neurol. 2021 Jun;8(6):1212–23.
- Tuovinen N, Stefani A, Mitterling T, Heidbreder A, Frauscher B, Gizewski ER, et al. Functional connectivity and topology in patients with restless legs syndrome: a case-control resting-state functional magnetic resonance imaging study. Eur J Neurol. 2021 Feb;28(2):448–58.
- Avigdor T, Abdallah C, von Ellenrieder N, Hedrich T, Rubino A, Lo Russo G, et al. Fast oscillations >40 Hz localize the epileptogenic zone: An electrical source imaging study using high-density electroencephalography. Clin Neurophysiol. 2021 Feb;132(2):568–80.
- Cesari M, Stefani A, Mitterling T, Frauscher B, Schönwald SV, Högl B. Sleep modelled as a continuous and dynamic process predicts healthy ageing better than traditional sleep scoring. Sleep Med. 2021 Jan;77:136–46.
- Frauscher B, von Ellenrieder N, Dolezalova I, Bouhadoun S, Gotman J, Peter-Derex L. Rapid Eye Movement Sleep Sawtooth Waves Are Associated with Widespread Cortical Activations. J Neurosci. 2020 Nov 11;40(46):8900–12.
- Bergmann M, Prieschl M, Stefani A, Heidbreder A, Walser G, Frauscher B, et al. A prospective controlled study about sleep disorders in drug resistant epilepsy. Sleep Med. 2020 Nov;75:434–40.
- Paquola C, Seidlitz J, Benkarim O, Royer J, Klimes P, Bethlehem RAI, et al. A multi-scale cortical wiring space links cellular architecture and functional dynamics in the human brain. PLoS Biol. 2020 Nov;18(11):e3000979.
- Peter-Derex L, Klimes P, Latreille V, Bouhadoun S, Dubeau F, Frauscher B. Sleep Disruption in Epilepsy: Ictal and Interictal Epileptic Activity Matter. Ann Neurol. 2020 Nov;88(5):907–20.
- Nevalainen P, von Ellenrieder N, Klimeš P, Dubeau F, Frauscher B, Gotman J. Association of fast ripples on intracranial EEG and outcomes after epilepsy surgery. Neurology. 2020 Oct 20;95(16):e2235–45.
- Royer J, Paquola C, Larivière S, Vos de Wael R, Tavakol S, Lowe AJ, et al. Myeloarchitecture gradients in the human insula: Histological underpinnings and association to intrinsic functional connectivity. Neuroimage. 2020 Aug 1;216:116859.
- Jobst BC, Bartolomei F, Diehl B, Frauscher B, Kahane P, Minotti L, et al. Intracranial EEG in the 21st Century. Epilepsy Currents. 2020 Jul 1;20(4):180–8.
- Latreille V, von Ellenrieder N, Peter-Derex L, Dubeau F, Gotman J, Frauscher B. The human K-complex: Insights from combined scalp-intracranial EEG recordings. Neuroimage. 2020 Jun;213:116748.
- Larivière S, Weng Y, Vos de Wael R, Royer J, Frauscher B, Wang Z, et al. Functional connectome contractions in temporal lobe epilepsy: Microstructural underpinnings and predictors of surgical outcome. Epilepsia. 2020 Jun;61(6):1221–33.
- Frauscher B. Localizing the epileptogenic zone. Curr Opin Neurol. 2020 Apr;33(2):198–206.
- von Ellenrieder N, Gotman J, Zelmann R, Rogers C, Nguyen DK, Kahane P, et al. How the Human Brain Sleeps: Direct Cortical Recordings of Normal Brain Activity. Ann Neurol. 2020 Feb;87(2):289–301.
- Mooij AH, Frauscher B, Gotman J, Huiskamp GJM. A skew-based method for identifying intracranial EEG channels with epileptic activity without detecting spikes, ripples, or fast ripples. Clin Neurophysiol. 2020 Jan;131(1):183–92.
- Stefani A, Mitterling T, Heidbreder A, Steiger R, Kremser C, Frauscher B, et al. Multimodal Magnetic Resonance Imaging reveals alterations of sensorimotor circuits in restless legs syndrome. Sleep. 2019 Dec 24;42(12).
- Klimes P, Cimbalnik J, Brazdil M, Hall J, Dubeau F, Gotman J, et al. NREM sleep is the state of vigilance that best identifies the epileptogenic zone in the interictal electroencephalogram. Epilepsia. 2019 Dec;60(12):2404–15.
- Cuello Oderiz C, von Ellenrieder N, Dubeau F, Eisenberg A, Gotman J, Hall J, et al. Association of Cortical Stimulation-Induced Seizure With Surgical Outcome in Patients With Focal Drug-Resistant Epilepsy. JAMA Neurol. 2019 Sep 1;76(9):1070–8.
- Schönberger J, Frauscher B, von Ellenrieder N, Avoli M, Dubeau F, Gotman J. Fast ripple analysis in human mesial temporal lobe epilepsy suggests two different seizure-generating mechanisms. Neurobiol Dis. 2019 Jul;127:374–81.
- Frauscher B, Gotman J. Sleep, oscillations, interictal discharges, and seizures in human focal epilepsy. Neurobiol Dis. 2019 Jul;127:545–53.
- Amiri M, Frauscher B, Gotman J. Interictal coupling of HFOs and slow oscillations predicts the seizure-onset pattern in mesiotemporal lobe epilepsy. Epilepsia. 2019 Jun;60(6):1160–70.
- Haschka D, Volani C, Stefani A, Tymoszuk P, Mitterling T, Holzknecht E, et al. Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome. Mov Disord. 2019 Jan;34(1):114–23.
- Thomschewski A, Hincapié AS, Frauscher B. Localization of the epileptogenic zone using high frequency oscillations. Frontiers in Neurology. 2019 Jan 1;10(FEB).
- Mooij AH, Frauscher B, Goemans SAM, Huiskamp GJM, Braun KPJ, Zijlmans M. Ripples in scalp EEGs of children: co-occurrence with sleep-specific transients and occurrence across sleep stages. Sleep. 2018 Nov 1;41(11).
- Stefani A, Frauscher B, Högl B. Diagnosis of REM sleep behavior disorder. In: Rapid-eye-movement sleep behavior disorder. 2018. p. 245–54.
- Frauscher B, von Ellenrieder N, Zelmann R, Rogers C, Nguyen DK, Kahane P, et al. High-Frequency Oscillations in the Normal Human Brain. Ann Neurol. 2018 Sep;84(3):374–85.
- Frauscher B, Joshi S, von Ellenrieder N, Nguyen DK, Dubeau F, Gotman J. Sharply contoured theta waves are the human correlate of ponto-geniculo-occipital waves in the primary visual cortex. Clin Neurophysiol. 2018 Aug;129(8):1526–33.
- von Ellenrieder N, Dan J, Frauscher B, Gotman J. Corrigendum to "Sparse asynchronous cortical generators can produce measurable scalp EEG signals" [Neuroimage 138 (2016) 123-133]. NeuroImage. 2018 May;172:631.
- Frauscher B, von Ellenrieder N, Zelmann R, Doležalová I, Minotti L, Olivier A, et al. Atlas of the normal intracranial electroencephalogram: neurophysiological awake activity in different cortical areas. Brain. 2018 Apr 1;141(4):1130–44.
- Auer M, Frauscher B, Hochleitner M, Högl B. Gender-Specific Differences in Access to Polysomnography and Prevalence of Sleep Disorders. J Womens Health (Larchmt). 2018 Apr;27(4):525–30.
- Haba-Rubio J, Frauscher B, Marques-Vidal P, Toriel J, Tobback N, Andries D, et al. Prevalence and determinants of rapid eye movement sleep behavior disorder in the general population. Sleep. 2018 Feb 1;41(2).
- Frauscher B, Bartolomei F, Kobayashi K, Cimbalnik J, van ’t Klooster MA, Rampp S, et al. High-frequency oscillations: The state of clinical research. Epilepsia. 2017 Aug;58(8):1316–29.
- Frauscher B, von Ellenrieder N, Dubeau F, Gotman J. Different seizure-onset patterns in mesiotemporal lobe epilepsy have a distinct interictal signature. Clin Neurophysiol. 2017 Jul;128(7):1282–9.
- von Ellenrieder N, Dubeau F, Gotman J, Frauscher B. Physiological and pathological high-frequency oscillations have distinct sleep-homeostatic properties. Neuroimage Clin. 2017;14:566–73.
- Mooij AH, Frauscher B, Amiri M, Otte WM, Gotman J. Differentiating epileptic from non-epileptic high frequency intracerebral EEG signals with measures of wavelet entropy. Clin Neurophysiol. 2016 Dec;127(12):3529–36.
- Ferri R, Fulda S, Allen RP, Zucconi M, Bruni O, Chokroverty S, et al. World Association of Sleep Medicine (WASM) 2016 standards for recording and scoring leg movements in polysomnograms developed by a joint task force from the International and the European Restless Legs Syndrome Study Groups (IRLSSG and EURLSSG). Sleep Med. 2016 Oct;26:86–95.
- von Ellenrieder N, Dan J, Frauscher B, Gotman J. Sparse asynchronous cortical generators can produce measurable scalp EEG signals. Neuroimage. 2016 Sep;138:123–33.
- Amiri M, Frauscher B, Gotman J. Phase-amplitude coupling is elevated in deep sleep and in the onset zone of focal epileptic seizures. Frontiers in Human Neuroscience. 2016 Aug 3;10:12.
- Delazer M, Zamarian L, Frauscher B, Mitterling T, Stefani A, Heidbreder A, et al. Oxygen desaturation during night sleep affects decision-making in patients with obstructive sleep apnea. J Sleep Res. 2016 Aug;25(4):395–403.
- Gan-Or Z, Mohsin N, Girard SL, Montplaisir JY, Ambalavanan A, Strong S, et al. The role of the melanoma gene MC1R in Parkinson disease and REM sleep behavior disorder. Neurobiol Aging. 2016 Jul;43:180.e7-180.e13.
- Frauscher B, von Ellenrieder N, Dubeau F, Gotman J. EEG desynchronization during phasic REM sleep suppresses interictal epileptic activity in humans. Epilepsia. 2016 Jun;57(6):879–88.
- von Ellenrieder N, Frauscher B, Dubeau F, Gotman J. Interaction with slow waves during sleep improves discrimination of physiologic and pathologic high-frequency oscillations (80-500 Hz). Epilepsia. 2016 Jun;57(6):869–78.
- Pizzo F, Frauscher B, Ferrari-Marinho T, Amiri M, Dubeau F, Gotman J. Detectability of Fast Ripples (>250 Hz) on the Scalp EEG: A Proof-of-Principle Study with Subdermal Electrodes. Brain Topogr. 2016 May;29(3):358–67.
- Heidbreder A, Frauscher B, Mitterling T, Boentert M, Schirmacher A, Hörtnagl P, et al. Not Only Sleepwalking But NREM Parasomnia Irrespective of the Type Is Associated with HLA DQB1*05:01. J Clin Sleep Med. 2016 Apr 15;12(4):565–70.
- Burnos S, Frauscher B, Zelmann R, Haegelen C, Sarnthein J, Gotman J. The morphology of high frequency oscillations (HFO) does not improve delineating the epileptogenic zone. Clin Neurophysiol. 2016 Apr;127(4):2140–8.
- Brayet P, Petit D, Frauscher B, Gagnon J-F, Gosselin N, Gagnon K, et al. Quantitative EEG of Rapid-Eye-Movement Sleep: A Marker of Amnestic Mild Cognitive Impairment. Clin EEG Neurosci. 2016 Apr;47(2):134–41.
- Pizzo F, Ferrari-Marinho T, Amiri M, Frauscher B, Dubeau F, Gotman J. When spikes are symmetric, ripples are not: Bilateral spike and wave above 80 Hz in focal and generalized epilepsy. Clin Neurophysiol. 2016 Mar;127(3):1794–802.
- van Klink N, Frauscher B, Zijlmans M, Gotman J. Relationships between interictal epileptic spikes and ripples in surface EEG. Clin Neurophysiol. 2016 Jan;127(1):143–9.
- Frauscher B, Bernasconi N, Caldairou B, von Ellenrieder N, Bernasconi A, Gotman J, et al. Interictal Hippocampal Spiking Influences the Occurrence of Hippocampal Sleep Spindles. Sleep. 2015 Dec 1;38(12):1927–33.
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- Frauscher B, von Ellenrieder N, Dubeau F, Gotman J. Scalp spindles are associated with widespread intracranial activity with unexpectedly low synchrony. Neuroimage. 2015 Jan 15;105:1–12.
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- Frauscher B, Egg R, Brandauer E, Ulmer H, Berger T, Poewe W, et al. Daytime sleepiness is not increased in mild to moderate multiple sclerosis: a pupillographic study. Sleep medicine. 2005 Nov;6(6):543–7.
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