Assistant Professor of Biomedical Engineering
Appointments and Affiliations
- Assistant Professor of Biomedical Engineering
- Assistant Professor in Biostatistics & Bioinformatics
- Assistant Professor of Computer Science
Contact Information
- Office Location: 101 Science Drive, Ciemas 2353A, Durham, NC 27705
- Office Phone: +1 706 442 2715
- Email Address: pranam.chatterjee@duke.edu
- Websites:
Education
- Ph.D. Massachusetts Institute of Technology, 2020
Research Interests
Integration of computational and experimental methodologies to design novel proteins for applications in genome editing, targeted protein modulation, and reproductive bioengineeringCourses Taught
- EGR 393: Research Projects in Engineering
- COMPSCI 590: Advanced Topics in Computer Science
- COMPSCI 394: Research Independent Study
- BME 791: Graduate Independent Study
- BME 590: Special Topics in Biomedical Engineering
- BME 494: Projects in Biomedical Engineering (GE)
- BME 493: Projects in Biomedical Engineering (GE)
- BME 390L: Special Topics with a Lab
In the News
Representative Publications
- Peng, Zhangzhi, Benjamin Schussheim, and Pranam Chatterjee. “PTM-Mamba: A PTM-Aware Protein Language Model with Bidirectional Gated Mamba Blocks.” BioRxiv, 2024. https://doi.org/10.1101/2024.02.28.581983.
- Chen, T., L. Hong, V. Yudistyra, S. Vincoff, and P. Chatterjee. “Generative design of therapeutics that bind and modulate protein states.” Current Opinion in Biomedical Engineering 28 (December 1, 2023). https://doi.org/10.1016/j.cobme.2023.100496.
- Brixi, Garyk, Tianzheng Ye, Lauren Hong, Tian Wang, Connor Monticello, Natalia Lopez-Barbosa, Sophia Vincoff, et al. “SaLT&PepPr is an interface-predicting language model for designing peptide-guided protein degraders.” Communications Biology 6, no. 1 (October 2023): 1081. https://doi.org/10.1038/s42003-023-05464-z.
- Zhao, Lin, Sabrina R. T. Koseki, Rachel A. Silverstein, Nadia Amrani, Christina Peng, Christian Kramme, Natasha Savic, et al. “PAM-flexible genome editing with an engineered chimeric Cas9.” Nature Communications 14, no. 1 (October 2023): 6175. https://doi.org/10.1038/s41467-023-41829-y.
- Liang, Shun-Qing, Pengpeng Liu, Karthikeyan Ponnienselvan, Sneha Suresh, Zexiang Chen, Christian Kramme, Pranam Chatterjee, et al. “Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag.” Nature Methods 20, no. 6 (June 2023): 898–907. https://doi.org/10.1038/s41592-023-01859-2.