Robert W. Carr, Jr., Distinguished Professor of Biomedical Engineering
Dr. Ramanujam is the Robert W. Carr Professor of Engineering and Professor of Cancer Pharmacology and Global Health at Duke University and co-program leader of the Radiation Oncology and Imaging Program (ROIP) at the Duke Cancer Institute. She founded the Center for Global Women’s Health Technologies (GWHT) in 2013 where she empowers trainees to create impactful solutions to improve the lives of women and girls globally. This center, since inception, has catalyzed new research activities and the development and commercialization of several technologies that advance prevention and treatment of cervical and breast cancer.
Dr. Ramanujam’s work has led to low-cost and efficient health care and home-based technology innovations that provide surveillance of cancer and its recurrence. To complement her translational efforts, Dr. Ramanujam’s work exploits the dynamic changes in tumor metabolism that allow cancers to go under the radar and recur in a stealth mode when conditions are favorable. She is also creating a liquid-based ablative therapy with dual roles - (1) to address the pressing issue of cancer control in environments where access to surgery is scarce, and (2) enhance tumor kill through a combination of necrosis and T cell infiltration occurring as a result of tumor antigen presentation following ablation.
Dr. Ramanujam has built several global initiatives. The most notable is a consortium to impact cervical cancer prevention in low resource settings. Her MacArthur Foundation 100&Change proposal, Women-Inspired Strategies for Health: A Revolution against Cervical Cancer (WISH) was recognized as one of the Top 100 of the 755 proposals submitted to this $100M grant competition (Macarthur 100&Change). In addition to her cervical cancer prevention initiative, she has also created a global women’s education program that intersects design-thinking, STEM concepts, and the U.N. Sustainable Development Goals to promote social justice awareness (IGNITE). She has launched an arts and storytelling initiative to raise awareness of sexual and reproductive health inequities (The (In) Visible Organ).
She has created two companies Zenalux and Calla Health to commercialize her technologies.
Calla Health, a GWHT venture, is centered on sustainably improving women's access to cancer prevention and creating innovations that increase wide scale surveillance of cervical pre-cancers and cancers. Zenalux Biomedical, in collaboration with Duke University, is developing a suite of optical microscopy and spectroscopy tools for preclinical and clinical applications in cancer research. Zenalux’ newest product offering is the Zenascope™ ZF1, a combined portable platform for optical imaging and spectroscopy to characterize the major axes of metabolism along with key vascular features.
Dr. Ramanujam has more than 20 patents to-date and more than 150 publications for screening, diagnostic, and surgical applications. She has received funding from a agencies including NIH R01s and R21s, NIH Bioengineering Partnerships, NCI Academic Industry Partnerships, NIH Small Business grants, DOD, Burroughs Wellcome Fund, DIHI: Innovation Jam, Prevent Cancer and USAID funding. As the director of the Center for Global Women’s Health Technologies, she has developed a network of 50+ partners including international academic institutions and hospitals, non-governmental organizations, ministries of health, and commercial partners; this consortium works to ensure the technologies developed at the center are adopted by cancer control programs in geographically and economically diverse healthcare settings.
Dr. Ramanujam has received a number of awards including the MIT TR100 Young Innovator award (MIT), the Global Indus Technovator award (MIT), the Stansell Family award (Duke), multiple Era of Hope Scholar awards (DoD), the Emerging Leader in Global Health Award (CUGH), the Social Impact Abie Award (AnitaB.org), the Biophotonics Technology Innovator Award (SPIE), the Women in Molecular Imaging Leadership Award (WMIC), the Michael S. Feld Biophotonics Award (OSA) and the Wom C Global Impact Award (Duke). She is a fellow of several optical and biomedical engineering societies including OSA, SPIE, and AIMBE. She is a Fulbright scholar and the 2020 IEEE Distinguished Lecturer. She is an elected member of the National Academy of Inventors. She has demonstrated her work’s global impact through presentations at the United Nations and TEDx events, and a number of national and international plenary talks. Her work has been featured in a number of venues including Medical Daily, Wired Magazine, NPR and several podcasts.
Appointments and Affiliations
- Robert W. Carr, Jr., Distinguished Professor of Biomedical Engineering
- Professor of Biomedical Engineering
- Director of Center for Global Women's Health Technologies
- Professor of Pharmacology and Cancer Biology
- Affiliate of the Duke Initiative for Science & Society
- Core Faculty Member, Duke-Margolis Center for Health Policy
- Member of the Duke Cancer Institute
- Office Location: 367 Gross Hall, 140 Science Drive, Durham, NC 27708
- Office Phone: (919) 660-5307
- B.S. University of Texas, Austin, 1989
- M.S. University of Texas, Austin, 1992
- Ph.D. University of Texas, Austin, 1995
Research InterestsInnovating on optical strategies to peer into the biological landscape of thick tissues. Technologies being developed in her lab leverage principles of optical spectroscopy, optical sectioning microscopy, and molecular imaging. Her research group is developing and applying these optically based tools for three problems in cancer: cancer screening in resource-limited settings, intra-operative margin assessment to detect residual disease during cancer surgery, and visualizing tumor hypoxia and metabolism in the context of cancer therapy and drug discovery. Prof. Ramanujam is leading a multi-disciplinary effort to translate these technologies to clinical applications in the breast, and cervix.
- BME 230L: Global Women's Health Technologies
- BME 290L: Intermediate Topics with Lab (GE)
- BME 494: Projects in Biomedical Engineering (GE)
- EGR 393: Research Projects in Engineering
- GLHLTH 230L: Global Women's Health Technologies
- GLHLTH 391: Independent Study in Global Health
- ISS 397: Bass Connections Information, Society & Culture Research Team
- ISS 398: Bass Connections Information, Society & Culture Research Team
- ISS 795: Bass Connections Information, Society & Culture Research Team
- ISS 796: Bass Connections Information, Society & Culture Research Team
- PHARM 493: Research Independent Study
- PHARM 494: Research Independent Study
In the News
- Duke Faculty Reexamine Their Roles as Scholars and Mentors in an Uncertain Time…
- Advancing Health Equity: Women’s Health Technologies (May 1, 2020 | Duke Mobile…
- The Human Dimension (Apr 30, 2020 | Diversity In Action Magazine)
- Necessity Is the Mother of Invention (Apr 10, 2020 | Thrive Global)
- Research Integrity Interviews Series: “If you treat people with integrity, you …
- UICC and WISH Project in the top 100 proposals selected by the MacArthur Founda…
- A Plan to Close the Cervical Cancer Inequity Gap Scores in Top 100 in MacArthur…
- Women's Health: It's Personal for Nimmi Ramanujam (Jan 28, 2020 | School of Med…
- USAID Announces $15.5 Million in Thirteen New Grants to Programs under the Deve…
- Prevent Cancer Foundation® awards $300,000 in global grants (Dec 1, 2019)
- How Tech Can Lead to Social Innovation: An Interview With Dr. Nimmi Ramanujam (…
- The Gynecological Exam is Finally Getting a Makeover (Sep 16, 2019 | Medium)
- Meet Dr. Nimmi Ramanujam, Social Impact Abie Award Winner (Aug 27, 2019 | Anita…
- Announcing the 2019 Cisco Global Problem Solver Challenge Winners. (May 20, 201…
- Ramanujam Receives Fulbright Global Scholar Award (Apr 22, 2019 | Pratt School …
- A Breakthrough in Cervical Cancer Treatment Inspires a Ruby Art Exhibit (Feb 27…
- Safe, Convenient, Affordable: How a Pocket Device Is Changing Women's Health (F…
- The Road to Biomedical Engineering Went Through Brahms (Oct 9, 2018 | Duke Arts)
- Three Engineers Named to National Academy of Inventors (Dec 13, 2017)
- New Tech Promises Easier Cervical Cancer Screening (May 31, 2017 | Pratt School…
- Duke Team's Portable Screening Device Takes Aim at Preventable Cervical Cancer …
- Researchers Aim to Make Cervical Cancer Screening Accessible to All (Dec 19, 20…
- Showing Washington the Future of Global Women’s Health (Nov 22, 2016 | Pratt Sc…
- New Collaborative Seed Grant Program Gives Eight Awards (Mar 16, 2016)
- Ramanujam Awarded Two Grants to Help Screen for Cervical Cancer in Africa (Aug …
- Duke Announces 2015 Distinguished Professors (May 1, 2015)
- DukeEngage Adds California-Based Programs Targeting Homeless and At-Risk Youth …
- Ramanujam Named Inaugural Recipient of Carr Professorship (Sep 24, 2014 | Pratt…
- Lab of Entrepreneurial Engineers (Sep 19, 2014)
- Global Research, Domestic Benefits (Jan 13, 2014)
- Duke Launches Global Womens Health Technologies Center (Oct 23, 2013)
- Ramanujam Promoted to SPIE Fellow (Jun 7, 2013)
- Natarajan, J., M. Krieger, N. Ramanujam, S. Vashist, and N. Bhatla. “Feasibility and Outcome of Training Field Workers to Use the Transvaginal Colposcope for Point of Care Diagnosis and Management of Precancerous Cervical Lesions.” Indian Journal of Gynecologic Oncology 21, no. 1 (March 1, 2023). https://doi.org/10.1007/s40944-022-00681-6.
- Natarajan, Jayashree, Sandeep Mathur, Sreenivas Vishnubhatla, Sunesh Kumar, Shachi Vashist, Nimmi Ramanujam, Seema Singhal, Jyoti Meena, Pranay Tanwar, and Neerja Bhatla. “Can portable Colposcopes Replace Standard-of-care Colposcopes? A Crossover Trial of Two Portable Colposcopes with a Standard-of-Care Video Colposcope.” Asian Pacific Journal of Cancer Prevention : Apjcp 23, no. 12 (December 2022): 4013–21. https://doi.org/10.31557/apjcp.2022.23.12.4013.
- Coole, Jackson B., David Brenes, Júlio César Possati-Resende, Márcio Antoniazzi, Bruno de Oliveira Fonseca, Yajur Maker, Alex Kortum, et al. “Development of a multimodal mobile colposcope for real-time cervical cancer detection.” Biomedical Optics Express 13, no. 10 (October 2022): 5116–30. https://doi.org/10.1364/boe.463253.
- Ramanujam, N., and M. Madonna. “Editorial overview: Biomedical engineering and women's health: Breaking new ground in gender- and sex-specific research.” Current Opinion in Biomedical Engineering 22 (June 1, 2022). https://doi.org/10.1016/j.cobme.2022.100392.
- Deutsch, Riley J., Victoria W. D’Agostino, Enakshi D. Sunassee, Michelle Kwan, Megan C. Madonna, Gregory Palmer, Brian T. Crouch, and Nimmi Ramanujam. “A Spectroscopic Technique to Simultaneously Characterize Fatty Acid Uptake, Mitochondrial Activity, Vascularity, and Oxygen Saturation for Longitudinal Studies In Vivo.” Metabolites 12, no. 5 (April 19, 2022). https://doi.org/10.3390/metabo12050369.