Lingchong You
Paul Ruffin Scarborough Associate Professor of Engineering
Dr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.Appointments and Affiliations
- Paul Ruffin Scarborough Associate Professor of Engineering
- Associate Professor of Biomedical Engineering
Contact Information
- Office Phone: (919) 660-8408
- Websites:
Education
- Ph.D. University of Wisconsin at Madison, 2002
- B.S.E. Chengdu University of Science and Technology (China), 1994
- M.S. University of Science and Technology of China (China), 0199
Research Interests
Dr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.
Specialties
Genomics
Computational Biology
Nonlinear Dynamics
Awards, Honors, and Distinctions
- Fellowships for Science and Engineering. David and Lucile Packard Foundation. 2006
Courses Taught
- BME 260L: Modeling Cellular and Molecular Systems
- BME 394: Projects in Biomedical Engineering (GE)
- BME 493: Projects in Biomedical Engineering (GE)
- BME 494: Projects in Biomedical Engineering (GE)
- BME 574: Modeling and Engineering Gene Circuits (GE, MC)
- BME 791: Graduate Independent Study
- BME 899: Special Readings in Biomedical Engineering
- CBB 574: Modeling and Engineering Gene Circuits (GE, MC)
- EGR 391: Projects in Engineering
- EGR 393: Research Projects in Engineering
In the News
- Lingchong You: Tales of the genetically altered, superhero bacteria swarmbot (May 2, 2016 | WFDD-Winston-Salem’s “SciWorks Radio” )
- Time Cues Help Keep Humans Looking Human (Apr 25, 2016)
- Antibiotics Don't Promote Swapping of Resistance Genes (Apr 11, 2016)
- Biologists turn bacteria into 'swarmbots' (Mar 2, 2016 | Gizmodo )
- Bioengineers Design 'Swarmbot' Cells That Die If They Leave the Confines of Their Capsule (Feb 29, 2016)
- Why Do Dividing Cells End Up the Same Size? (Jun 4, 2015)
- Lingchong You comments: Paper test can detect Ebola strains (Oct 27, 2014 | BBC News )
- Dispersal Patterns Key to Invasive Species' Success (Jan 21, 2014)
- Chinese-Americans protest Kimmel skit in front of ABC station in downtown Raleigh (Nov 11, 2013 | The News & Observer )
- Growing Bacteria Keep Time, Know Their Place (Oct 8, 2013)
Representative Publications
- Huang, S; Srimani, JK; Lee, AJ; Zhang, Y; Lopatkin, AJ; Leong, KW; You, L, Dynamic control and quantification of bacterial population dynamics in droplets., Biomaterials, vol 61 (2015), pp. 239-245 [abs].
- Tanouchi, Y; Pai, A; Park, H; Huang, S; Stamatov, R; Buchler, NE; You, L, A noisy linear map underlies oscillations in cell size and gene expression in bacteria., Nature, vol 523 no. 7560 (2015), pp. 357-360 [abs].
- Meredith, HR; Lopatkin, AJ; Anderson, DJ; You, L, Bacterial temporal dynamics enable optimal design of antibiotic treatment., PLoS computational biology, vol 11 no. 4 (2015) [abs].
- Lee, TJ; Wong, J; Bae, S; Lee, AJ; Lopatkin, A; Yuan, F; You, L, A power-law dependence of bacterial invasion on mammalian host receptors., PLoS computational biology, vol 11 no. 4 (2015) [abs].
- Meredith, HR; Srimani, JK; Lee, AJ; Lopatkin, AJ; You, L, Collective antibiotic tolerance: mechanisms, dynamics and intervention., Nature Chemical Biology, vol 11 no. 3 (2015), pp. 182-188 [abs].