Lingchong You

Lingchong You

Paul Ruffin Scarborough Associate Professor of Engineering

Dr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.

Appointments and Affiliations

  • Paul Ruffin Scarborough Associate Professor of Engineering
  • Associate Professor of Biomedical Engineering
  • Associate Professor in Molecular Genetics and Microbiology

Contact Information

  • Office Location: 2355 CIEMAS, 101 Science Drive, Durham, NC 27708
  • Office Phone: (919) 660-8408
  • Websites:

Education

  • Ph.D. University of Wisconsin at Madison, 2002
  • B.S.E. Chengdu University of Science and Technology (China), 1994
  • M.S. University of Science and Technology of China (China), 0199

Research Interests

Dr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.

Specialties

Genomics
Computational Biology
Nonlinear Dynamics

Awards, Honors, and Distinctions

  • Fellowships for Science and Engineering. David and Lucile Packard Foundation. 2006

Courses Taught

  • BME 260L: Modeling Cellular and Molecular Systems
  • BME 394: Projects in Biomedical Engineering (GE)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 574: Modeling and Engineering Gene Circuits (GE, MC)
  • BME 791: Graduate Independent Study
  • BME 899: Special Readings in Biomedical Engineering
  • CBB 574: Modeling and Engineering Gene Circuits (GE, MC)
  • EGR 391: Projects in Engineering
  • EGR 393: Research Projects in Engineering

In the News

Representative Publications

  • Huang, S; Srimani, JK; Lee, AJ; Zhang, Y; Lopatkin, AJ; Leong, KW; You, L, Dynamic control and quantification of bacterial population dynamics in droplets., Biomaterials, vol 61 (2015), pp. 239-245 [10.1016/j.biomaterials.2015.05.038] [abs].
  • Tanouchi, Y; Pai, A; Park, H; Huang, S; Stamatov, R; Buchler, NE; You, L, A noisy linear map underlies oscillations in cell size and gene expression in bacteria., Nature, vol 523 no. 7560 (2015), pp. 357-360 [10.1038/nature14562] [abs].
  • Meredith, HR; Lopatkin, AJ; Anderson, DJ; You, L, Bacterial temporal dynamics enable optimal design of antibiotic treatment., PLoS computational biology, vol 11 no. 4 (2015) [10.1371/journal.pcbi.1004201] [abs].
  • Lee, TJ; Wong, J; Bae, S; Lee, AJ; Lopatkin, A; Yuan, F; You, L, A power-law dependence of bacterial invasion on mammalian host receptors., PLoS computational biology, vol 11 no. 4 (2015) [10.1371/journal.pcbi.1004203] [abs].
  • Meredith, HR; Srimani, JK; Lee, AJ; Lopatkin, AJ; You, L, Collective antibiotic tolerance: mechanisms, dynamics and intervention., Nature Chemical Biology, vol 11 no. 3 (2015), pp. 182-188 [10.1038/nchembio.1754] [abs].