Lingchong You


Professor of Biomedical Engineering

The You lab uses a combination of mathematical modeling, machine learning, and quantitative experiments to elucidate principles underlying the dynamics of microbial communities in time and space and to control these dynamics for applications in computation, engineering, and medicine.

Appointments and Affiliations

  • Professor of Biomedical Engineering
  • Associate Professor in Molecular Genetics and Microbiology
  • Professor in Molecular Genetics and Microbiology

Contact Information


  • Ph.D. University of Wisconsin - Madison, 2002
  • M.S. University of Science and Technology of China (China), 1997
  • B.S.E. Chengdu University of Science and Technology (China), 1994

Research Interests

Quantitative biology, synthetic biology, machine learning, antibiotic resistance, microbiome

Awards, Honors, and Distinctions

  • Faculty Early Career Development (CAREER) Program. National Science Foundation. 2010
  • Fellowships for Science and Engineering. David and Lucile Packard Foundation. 2006

Courses Taught

  • BIOLOGY 293-1: Research Independent Study
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 574: Modeling and Engineering Gene Circuits (GE, MC)
  • BME 791: Graduate Independent Study
  • CBB 574: Modeling and Engineering Gene Circuits (GE, MC)
  • EGR 393: Research Projects in Engineering
  • MGM 293: Research Independent Study I
  • MGM 593: Research Independent Study
  • PHARM 394: Research Independent Study
  • PHARM 493: Research Independent Study

In the News

Representative Publications

  • Chen, B; Kang, W; Sun, J; Zhu, R; Yu, Y; Xia, A; Yu, M; Wang, M; Han, J; Chen, Y; Teng, L; Tian, Q; Yu, Y; Li, G; You, L; Liu, Z; Dai, Z, Programmable living assembly of materials by bacterial adhesion., Nature Chemical Biology (2021) [10.1038/s41589-021-00934-z] [abs].
  • Duncker, KE; Holmes, ZA; You, L, Engineered microbial consortia: strategies and applications., Microbial Cell Factories, vol 20 no. 1 (2021) [10.1186/s12934-021-01699-9] [abs].
  • Wang, T; Weiss, A; Ha, Y; You, L, Predicting plasmid persistence in microbial communities by coarse-grained modeling., Bioessays, vol 43 no. 9 (2021) [10.1002/bies.202100084] [abs].
  • Son, H-I; Weiss, A; You, L, Design patterns for engineering genetic stability., Current Opinion in Biomedical Engineering, vol 19 (2021) [10.1016/j.cobme.2021.100297] [abs].
  • Dai, Z; Yang, X; Wu, F; Wang, L; Xiang, K; Li, P; Lv, Q; Tang, J; Dohlman, A; Dai, L; Shen, X; You, L, Living fabrication of functional semi-interpenetrating polymeric materials., Nature Communications, vol 12 no. 1 (2021) [10.1038/s41467-021-23812-7] [abs].