Lingchong You

You

Professor of Biomedical Engineering

Dr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.

Appointments and Affiliations

  • Professor of Biomedical Engineering
  • Associate Professor in Molecular Genetics and Microbiology

Contact Information

  • Office Location: 2355 CIEMAS, 101 Science Drive, Durham, NC 27708
  • Office Phone: (919) 660-8408
  • Websites:

Education

  • Ph.D. University of Wisconsin at Madison, 2002
  • M.S. University of Science and Technology of China (China), 1997
  • B.S.E. Chengdu University of Science and Technology (China), 1994

Research Interests

Computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.

Awards, Honors, and Distinctions

  • Faculty Early Career Development (CAREER) Program. National Science Foundation. 2010
  • Fellowships for Science and Engineering. David and Lucile Packard Foundation. 2006

Courses Taught

  • BME 260L: Modeling Cellular and Molecular Systems
  • BME 394: Projects in Biomedical Engineering (GE)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 574: Modeling and Engineering Gene Circuits (GE, MC)
  • BME 590: Special Topics in Biomedical Engineering
  • BME 791: Graduate Independent Study
  • BME 792: Continuation of Graduate Independent Study
  • COMPSCI 391: Independent Study
  • COMPSCI 394: Research Independent Study
  • EGR 393: Research Projects in Engineering
  • ISS 391: Bass Connections in Information Science and Culture: Independent Study Project
  • MGM 293: Research Independent Study I
  • MGM 593: Research Independent Study
  • PHARM 394: Research Independent Study
  • PHARM 493: Research Independent Study

In the News

Representative Publications

  • Dai, Z; Lee, AJ; Roberts, S; Sysoeva, TA; Huang, S; Dzuricky, M; Yang, X; Zhang, X; Liu, Z; Chilkoti, A; You, L, Versatile biomanufacturing through stimulus-responsive cell-material feedback., Nature Chemical Biology, vol 15 no. 10 (2019), pp. 1017-1024 [10.1038/s41589-019-0357-8] [abs].
  • Wang, S; Fan, K; Luo, N; Cao, Y; Wu, F; Zhang, C; Heller, KA; You, L, Massive computational acceleration by using neural networks to emulate mechanism-based biological models., Nature Communications, vol 10 no. 1 (2019) [10.1038/s41467-019-12342-y] [abs].
  • Ma, HR; You, L, Polar-opposite fates., Nature Chemical Biology, vol 15 no. 9 (2019), pp. 850-852 [10.1038/s41589-019-0337-z] [abs].
  • Meredith, HR; Andreani, V; Ma, HR; Lopatkin, AJ; Lee, AJ; Anderson, DJ; Batt, G; You, L, Applying ecological resistance and resilience to dissect bacterial antibiotic responses., Science Advances, vol 4 no. 12 (2018) [10.1126/sciadv.aau1873] [abs].
  • Dong, P; Maddali, MV; Srimani, JK; Thélot, F; Nevins, JR; Mathey-Prevot, B; You, L, Author Correction: Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control., Nature Communications, vol 9 no. 1 (2018) [10.1038/s41467-018-07169-y] [abs].