Paul Ruffin Scarborough Associate Professor of EngineeringDr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.
Appointments and Affiliations
- Paul Ruffin Scarborough Associate Professor of Engineering
- Associate Professor of Biomedical Engineering
- Associate Professor in Molecular Genetics and Microbiology
- Office Location: 2355 CIEMAS, 101 Science Drive, Durham, NC 27708
- Office Phone: (919) 660-8408
- Ph.D. University of Wisconsin at Madison, 2002
- M.S. University of Science and Technology of China (China), 1997
- B.S.E. Chengdu University of Science and Technology (China), 1994
Dr. You's research interest focus on computational systems biology & synthetic biology, including mathematical modeling of cellular networks; mechanisms of information processing by gene networks; design, modeling and construction of robust gene networks for applications in engineering and medicine.
Awards, Honors, and Distinctions
- Fellowships for Science and Engineering. David and Lucile Packard Foundation. 2006
- BME 260L: Modeling Cellular and Molecular Systems
- BME 394: Projects in Biomedical Engineering (GE)
- BME 493: Projects in Biomedical Engineering (GE)
- BME 494: Projects in Biomedical Engineering (GE)
- BME 574: Modeling and Engineering Gene Circuits (GE, MC)
- BME 791: Graduate Independent Study
- BME 899: Special Readings in Biomedical Engineering
- CBB 574: Modeling and Engineering Gene Circuits (GE, MC)
- COMPSCI 391: Independent Study
- EGR 391: Projects in Engineering
- EGR 393: Research Projects in Engineering
- ISS 391: Bass Connections in Information Science and Culture: Independent Study Project
- MGM 293: Research Independent Study I
- MGM 593: Research Independent Study
In the News
- Where Are All the Germs? Students Explore Duke's Microbiome (Dec 7, 2017 | Center for Genomic and Computational Biology )
- Lingchong You: Tales of the genetically altered, superhero bacteria swarmbot (May 2, 2016 | WFDD-Winston-Salem’s “SciWorks Radio” )
- Time Cues Help Keep Humans Looking Human (Apr 25, 2016)
- Antibiotics Don't Promote Swapping of Resistance Genes (Apr 11, 2016)
- Biologists turn bacteria into 'swarmbots' (Mar 2, 2016 | Gizmodo )
- Bioengineers Design 'Swarmbot' Cells That Die If They Leave the Confines of Their Capsule (Feb 29, 2016)
- Why Do Dividing Cells End Up the Same Size? (Jun 4, 2015)
- Lingchong You comments: Paper test can detect Ebola strains (Oct 27, 2014 | BBC News )
- Dispersal Patterns Key to Invasive Species' Success (Jan 21, 2014)
- Chinese-Americans protest Kimmel skit in front of ABC station in downtown Raleigh (Nov 11, 2013 | The News & Observer )
- Growing Bacteria Keep Time, Know Their Place (Oct 8, 2013)
- Wu, F; You, L, Hacking DNA copy number for circuit engineering., Nature Genetics, vol 49 no. 8 (2017), pp. 1164-1165 [10.1038/ng.3923] [abs].
- Lopatkin, AJ; Sysoeva, TA; You, L, Dissecting the effects of antibiotics on horizontal gene transfer: Analysis suggests a critical role of selection dynamics., Bioessays, vol 38 no. 12 (2016), pp. 1283-1292 [10.1002/bies.201600133] [abs].
- Cao, Y; Lopatkin, A; You, L, Elements of biological oscillations in time and space., Nature Structural & Molecular Biology, vol 23 no. 12 (2016), pp. 1030-1034 [10.1038/nsmb.3320] [abs].
- Zhang, C; Tsoi, R; Wu, F; You, L, Processing Oscillatory Signals by Incoherent Feedforward Loops., PLoS computational biology, vol 12 no. 9 (2016) [10.1371/journal.pcbi.1005101] [abs].
- Lopatkin, AJ; Huang, S; Smith, RP; Srimani, JK; Sysoeva, TA; Bewick, S; Karig, DK; You, L, Antibiotics as a selective driver for conjugation dynamics., Nature microbiology, vol 1 no. 6 (2016) [10.1038/nmicrobiol.2016.44] [abs].