Joel Henderson Collier

Joel Henderson Collier

Associate Professor in the Department of Biomedical Engineering

The Collier Lab designs biomaterials for a range of biomedical applications, with a focus on understanding and controlling adaptive immune responses.  Most materials investigated are created from molecular assemblies- proteins, peptides or bioconjugates that self-organize into useful structures such as nanofibers, gels, and particles. 

These biomaterials are being developed as novel treatments for infectious diseases, cancer, wound healing, and chronic inflammation.  Additionally, as these strategies are developed, basic insights into how materials engage the immune system are uncovered.

Appointments and Affiliations

  • Associate Professor in the Department of Biomedical Engineering
  • Associate Professor in the Department of Immunology

Contact Information

Education

  • Ph.D. Northwestern University, 2003

Research Interests

Collier's research interests relate to the design of biomaterials for a range of biomedical applications, with a focus on understanding and controlling adaptive immune responses. Most materials investigated are created from molecular assemblies- proteins, peptides or bioconjugates that self-organize into useful structures such as nanofibers, gels, and particles.

Awards, Honors, and Distinctions

  • 2015 Biomaterials Science Lectureship. Royal Society of Chemistry Publishing. 2015
  • Distinguished Investigator (junior). University of Chicago, Biological Science Division. 2012

Courses Taught

  • BME 525: Biomedical Materials and Artificial Organs (GE, BB)
  • BME 791: Graduate Independent Study
  • BME 792: Graduate Independent Study
  • BME 899: Special Readings in Biomedical Engineering
  • ME 518: Biomedical Materials and Artificial Organs (GE, BB)

Representative Publications

  • Sun, T; Han, H; Hudalla, GA; Wen, Y; Pompano, RR; Collier, JH, Thermal stability of self-assembled peptide vaccine materials., Acta Biomaterialia, vol 30 (2016), pp. 62-71 [abs].
  • Wen, Y; Collier, JH, Supramolecular peptide vaccines: tuning adaptive immunity., Current Opinion in Immunology, vol 35 (2015), pp. 73-79 [abs].
  • Pompano, RR; Chen, J; Verbus, EA; Han, H; Fridman, A; McNeely, T; Collier, JH; Chong, AS, Titrating T-cell epitopes within self-assembled vaccines optimizes CD4+ helper T cell and antibody outputs., Advanced healthcare materials, vol 3 no. 11 (2014), pp. 1898-1908 [abs].
  • Hudalla, GA; Sun, T; Gasiorowski, JZ; Han, H; Tian, YF; Chong, AS; Collier, JH, Gradated assembly of multiple proteins into supramolecular nanomaterials., Nature Materials, vol 13 no. 8 (2014), pp. 829-836 [abs].
  • Chen, J; Pompano, RR; Santiago, FW; Maillat, L; Sciammas, R; Sun, T; Han, H; Topham, DJ; Chong, AS; Collier, JH, The use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation., Biomaterials, vol 34 no. 34 (2013), pp. 8776-8785 [abs].
  • Hudalla, GA; Modica, JA; Tian, YF; Rudra, JS; Chong, AS; Sun, T; Mrksich, M; Collier, JH, A self-adjuvanting supramolecular vaccine carrying a folded protein antigen., Advanced healthcare materials, vol 2 no. 8 (2013), pp. 1114-1119 [abs].
  • Jung, JP; Moyano, JV; Collier, JH, Multifactorial optimization of endothelial cell growth using modular synthetic extracellular matrices., Integrative Biology, vol 3 no. 3 (2011), pp. 185-196 [abs].
  • Rudra, JS; Tian, YF; Jung, JP; Collier, JH, A self-assembling peptide acting as an immune adjuvant., Proceedings of the National Academy of Sciences of USA, vol 107 no. 2 (2010), pp. 622-627 [abs].