Charles A Gersbach
Rooney Family Associate Professor of Biomedical Engineering
Appointments and Affiliations
- Rooney Family Associate Professor of Biomedical Engineering
- Associate Professor of Biomedical Engineering
- Associate Professor of Orthopaedic Surgery
- Affiliate of the Duke Initiative for Science & Society
- Member of the Duke Cancer Institute
- Office Phone: (919) 613-2147
- Email Address: email@example.com
- Ph.D. Georgia Institute of Technology, 2006
- B.S. Georgia Institute of Technology, 2001
Dr. Gersbach's research interests are in gene therapy, biomolecular and cellular engineering, regenerative medicine, and synthetic biology.
Tissue Repair, Tissue Engineering
Polymer and Protein Engineering
- BME 260L: Modeling Cellular and Molecular Systems
- BME 394: Projects in Biomedical Engineering (GE)
- BME 493: Projects in Biomedical Engineering (GE)
- BME 494: Projects in Biomedical Engineering (GE)
- BME 562: Biology by Design (GE, MC)
- BME 711S: Biological Engineering Seminar Series (CBIMMS and CBTE)
- BME 712S: Biological Engineering Seminar Series (CBIMMS and CBTE)
- BME 791: Graduate Independent Study
- EGR 391: Projects in Engineering
- EGR 393: Research Projects in Engineering
- GENOME 293: Research Independent Study Genome Sciences
- GENOME 294: Research Independent Study Genome Sciences
- ME 717S: Biological Engineering Seminar Series (CBIMMS and CBTE)
- ME 718S: Biological Engineering Seminar Series (CBIMMS and CBTE)
In the News
- Duke Awards Distinguished Professorships, Inducts New Bass Society Members (May 5, 2016)
- Gene editing treats disease in mice (Jan 4, 2016 | BBC News )
- Gene editing offers hope for treating Duchenne muscular dystrophy, studies find (Jan 4, 2016 | The New York Times )
- CRISPR Treats Genetic Disorder in Adult Mammal (Dec 31, 2015)
- Pratt Research Brings Precise Control to Gene Expression (Oct 27, 2015)
- Studying the Harm and Healing Power of Steroids (May 26, 2015)
- Engineers gain control of gene activity; new therapies may be ahead (Apr 6, 2015)
- Bacterial Defense Mechanism Targets Duchenne Muscular Dystrophy (Feb 19, 2015)
- Bacterial Defense Mechanism Targets Duchenne Muscular Dystrophy (Feb 18, 2015)
- Lighting Up the Duke 'D' With Genes (Feb 10, 2015)
- Black, JB; Adler, AF; Wang, HG; D'Ippolito, AM; Hutchinson, HA; Reddy, TE; Pitt, GS; Leong, KW; Gersbach, CA, Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells., Cell Stem Cell, vol 19 no. 3 (2016), pp. 406-414 [abs].
- Lee, J; Xu, L; Gibson, TM; Gersbach, CA; Sullenger, BA, Differential effects of toll-like receptor stimulation on mRNA-driven myogenic conversion of human and mouse fibroblasts., Biochemical and Biophysical Research Communications, vol 478 no. 3 (2016), pp. 1484-1490 [10.1016/j.bbrc.2016.08.159] [abs].
- Moutos, FT; Glass, KA; Compton, SA; Ross, AK; Gersbach, CA; Guilak, F; Estes, BT, Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing., Proceedings of the National Academy of Sciences of USA, vol 113 no. 31 (2016), pp. E4513-E4522 [abs].
- Nelson, CE; Gersbach, CA, Engineering Delivery Vehicles for Genome Editing, Annual Review of Chemical and Biomolecular Engineering, vol 7 no. 1 (2016), pp. 637-662 [10.1146/annurev-chembioeng-080615-034711] [abs].
- Landau, DJ; Brooks, ED; Perez-Pinera, P; Amarasekara, H; Mefferd, A; Li, S; Bird, A; Gersbach, CA; Koeberl, DD, In Vivo Zinc Finger Nuclease-mediated Targeted Integration of a Glucose-6-phosphatase Transgene Promotes Survival in Mice With Glycogen Storage Disease Type IA., Molecular Therapy, vol 24 no. 4 (2016), pp. 697-706 [abs].