Brian T Crouch

Assistant Research Professor in the Department of Biomedical Engineering

Dr. Crouch is an Assistant Research Professor in the Department of Biomedical Engineering and the Assistant Director of Research for the Center for Global Women's Health Technologies (GWHT). Dr. Crouch’s research interests intersect oncology, translational research, and global health, with a particular focus on diagnostics and therapeutics in low-resource settings. He is an expert in translating diagnostic technologies from the bench to bedside using in vitro cell culture and cell-based assays, small animal models, fluorescence microscopy, image processing, machine learning, and clinical trial design.

Appointments and Affiliations

  • Assistant Research Professor in the Department of Biomedical Engineering

Contact Information

  • Office Location: 140 Science Drive, 373 Gross Hall, Durham, NC 27708
  • Office Phone: (919) 660-5249
  • Email Address: brian.crouch@duke.edu

Education

  • Ph.D. Duke University, 2018

Research Interests

Developing novel, low cost technologies for cancer diagnostics and therapeutics with applications in resource limited settings. Particular focus on innovative strategies to induce a robust anti-tumor immune response following ablative therapy.

Courses Taught

  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)
  • EGR 393: Research Projects in Engineering
  • EGR 491: Projects in Engineering
  • GLHLTH 395T: Bass Connections Global Health Research Team
  • GLHLTH 396T: Bass Connections Global Health Research Team
  • GLHLTH 795T: Bass Connections Global Health Research Team
  • GLHLTH 796T: Bass Connections Global Health Research Team

Representative Publications

  • Quang, Tri T., Jeffrey Yang, Michele L. Kaluzienski, Anna Parrish, Asma Farooqui, David Katz, Brian Crouch, Nimmi Ramanujam, and Jenna L. Mueller. “In Vivo Evaluation of Safety and Efficacy of Ethyl Cellulose-Ethanol Tissue Ablation in a Swine Cervix Model.” Bioengineering (Basel, Switzerland) 10, no. 11 (October 2023): 1246. https://doi.org/10.3390/bioengineering10111246.
  • Madonna, Megan C., Douglas B. Fox, Brian T. Crouch, Jihong Lee, Caigang Zhu, Amy F. Martinez, James V. Alvarez, and Nirmala Ramanujam. “Data from Optical Imaging of Glucose Uptake and Mitochondrial Membrane Potential to Characterize Her2 Breast Tumor Metabolic Phenotypes,” April 3, 2023. https://doi.org/10.1158/1541-7786.c.6541071.
  • Madonna, Megan C., Douglas B. Fox, Brian T. Crouch, Jihong Lee, Caigang Zhu, Amy F. Martinez, James V. Alvarez, and Nirmala Ramanujam. “Supplementary figures and captions 1-5 from Optical Imaging of Glucose Uptake and Mitochondrial Membrane Potential to Characterize Her2 Breast Tumor Metabolic Phenotypes,” April 3, 2023. https://doi.org/10.1158/1541-7786.22515396.v1.
  • Madonna, Megan C., Douglas B. Fox, Brian T. Crouch, Jihong Lee, Caigang Zhu, Amy F. Martinez, James V. Alvarez, and Nirmala Ramanujam. “Supplementary figures and captions 1-5 from Optical Imaging of Glucose Uptake and Mitochondrial Membrane Potential to Characterize Her2 Breast Tumor Metabolic Phenotypes,” April 3, 2023. https://doi.org/10.1158/1541-7786.22515396.
  • Wang, Roujia, Daniel A. Alvarez, Brian T. Crouch, Aditi Pilani, Christopher Lam, Caigang Zhu, Philip Hughes, David Katz, Timothy Haystead, and Nirmala Ramanujam. “Understanding the sources of errors in ex vivo Hsp90 molecular imaging for rapid-on-site breast cancer diagnosis.” Biomed Opt Express 12, no. 4 (April 1, 2021): 2299–2311. https://doi.org/10.1364/BOE.418818.