Amanda Randles

Alfred Winborne and Victoria Stover Mordecai Assistant Professor of Biomedical Sciences

My research in biomedical simulation and high-performance computing focuses on the development of new computational tools that we use to provide insight into the localization and development of human diseases ranging from atherosclerosis to cancer. 

Appointments and Affiliations

• Alfred Winborne and Victoria Stover Mordecai Assistant Professor of Biomedical Sciences
• Assistant Professor of Biomedical Engineering
• Assistant Professor of Computer Science
• Member of the Duke Cancer Institute

Contact Information

• Office Location: 303 Gross Hall, 140 Science Dr., Durham, NC 27708
• Office Phone: (919) 660-5425
• Email Address: amanda.randles@duke.edu
• Websites:
  • Google Scholar
  • Randles Lab Site

Education

• Ph.D. Harvard University , 2013

Research Interests

Biomedical simulation and high-performance computing

Awards, Honors, and Distinctions

• Senior Member. National Academy of Inventors. 2019
• IEEE-CS Technical Consortium on High Performance Computing (TCHPC) Award for Excellence for Early Career Researchers in High Performance Computing. IEEE. 2017
• Grace Murray Hopper Award. ACM. 2017
• MIT TR35 Visionary. MIT TR35. 2017
• Ralph E. Powe Junior Faculty Enhancement Award. Oak Ridge Associated Universities. 2016
• Best Paper, IEEE International Conference on Computational Science (ICCS) 2015. IEEE. 2015
• Gordon Bell Finalist. ACM. 2015
• Early Independence Award. NIH. 2014
• Lawrence Fellowship. Lawrence Livermore National Laboratory. 2013
• U.S. Delegate . Heidelberg Laureate Forum. 2013
• Anita Borg Memorial Scholarship. Google. 2012
• George Michael Memorial High Performance Computing Fellowship. ACM/IEEE. 2012
• U.S. Delegate . Lindau Nobel Laureates and Students Meeting Dedicated to Physics. 2012
• Computational Science Graduate Fellowship. Department of Energy. 2010
• George Michael Memorial High Performance Computing Fellowship. ACM/IEEE. 2010
• Gordon Bell Finalist. ACM. 2010
• Graduate Research Fellowship. National Science Foundation. 2009

Courses Taught

• BME 307: Transport Phenomena in Biological Systems (AC or GE, BB)
• BME 307D: Transport Phenomena in Biological Systems (AC or GE, BB)
• BME 493: Projects in Biomedical Engineering (GE)
• BME 494: Projects in Biomedical Engineering (GE)
• BME 590L: Special Topics with Lab
• BME 791: Graduate Independent Study
• CEE 307: Transport Phenomena in Biological Systems (AC or GE, BB)
• COMPSCI 394: Research Independent Study

In the News

• The Race to Split a Ventilator (Dec 9, 2020)
• Virtual Reality Blood Flow Simulation To Improve Cardiovascular Interventions (May 14, 2020 | Pratt School of Engineering)
• Randles' Cancer Simulations Aims to Be Critical Step Toward Understanding Cancer Metastasis (Sep 11, 2019 | Duke Cancer Institute)
• A Revolutionary Picture of Blood Flow Opens New Avenues for Disease Diagnosis and Treatment (Aug 8, 2019 | Pratt School of Engineering)
• Randles Selected to Help Pilot First U.S. Exascale Computer (Jul 6, 2018 | Pratt School of Engineering)
• Duke University Models How and Where Blood flow Impacts Health (Nov 1, 2017)
• Plumbing Virtual Vessels (Sep 21, 2017)
• Supercomputer copies whole-body blood flow (Mar 17, 2016 | BBC News)
• New Collaborative Seed Grant Program Gives Eight Awards (Mar 16, 2016)
• NIH Features Randles Research on Fighting Cancer With Supercomputers (Nov 19, 2015)
• Experts put health issues firmly in the spotlight (Sep 14, 2015 | China Daily)
• Randles Named Finalist for Supercomputing’s Top Honor (Aug 27, 2015 | Pratt School of Engineering)
• Amanda Randles: Computing Complex Biological Systems (Jun 5, 2015 | Pratt School of Engineering)

Representative Publications

• Feiger, B; Adebiyi, A; Randles, A, Multiscale modeling of blood flow to assess neurological complications in patients supported by venoarterial extracorporeal membrane oxygenation., Computers in Biology and Medicine, vol 129 (2020) [10.1016/j.compbiomed.2020.104155] [abs].
• Kaplan, M; Kneifel, C; Orlikowski, V; Dorff, J; Newton, M; Howard, A; Shinn, D; Bishawi, M; Chidyagwai, S; Balogh, P; Randles, A, Cloud Computing for COVID-19: Lessons Learned from Massively Parallel Models of Ventilator Splitting, Computing in Science & Engineering, vol 22 no. 6 (2020), pp. 37-47 [10.1109/MCSE.2020.3024062] [abs].
• Pepona, M; Balogh, P; Puleri, DF; Hynes, WF; Robertson, C; Dubbin, K; Alvarado, J; Moya, ML; Randles, A, Investigating the Interaction Between Circulating Tumor Cells and Local Hydrodynamics via Experiment and Simulations., Cellular and Molecular Bioengineering, vol 13 no. 5 (2020), pp. 527-540 [10.1007/s12195-020-00656-7] [abs].
• Jang, L; Alvarado, J; Pepona, M; Wasson, E; Nash, L; Ortega, J; Randles, A; Maitland, D; Moya, M; Hynes, WF, Three-dimensional bioprinting of aneurysm-bearing tissue structure for endovascular deployment of embolization coils., Biofabrication (2020) [10.1088/1758-5090/abbb9b] [abs].
• Hynes, WF; Pepona, M; Robertson, C; Alvarado, J; Dubbin, K; Triplett, M; Adorno, JJ; Randles, A; Moya, ML, Examining metastatic behavior within 3D bioprinted vasculature for the validation of a 3D computational flow model., Science Advances, vol 6 no. 35 (2020) [10.1126/sciadv.abb3308] [abs].