Alfred Winborne and Victoria Stover Mordecai Associate Professor of Biomedical Sciences
My research in biomedical simulation and high-performance computing focuses on the development of new computational tools that we use to provide insight into the localization and development of human diseases ranging from atherosclerosis to cancer.
Appointments and Affiliations
- Alfred Winborne and Victoria Stover Mordecai Associate Professor of Biomedical Sciences
- Associate Professor of Biomedical Engineering
- Assistant Professor in the Thomas Lord Department of Mechanical Engineering and Materials Science
- Assistant Professor of Computer Science
- Member of the Duke Cancer Institute
Contact Information
- Office Location: Wilkinson Building, Room No. 325, 534 Research Drive, Durham, NC 27708
- Office Phone: (919) 660-6962
- Email Address: amanda.randles@duke.edu
- Websites:
Education
- Ph.D. Harvard University , 2013
Research Interests
Biomedical simulation and high-performance computingCourses Taught
- BME 307: Transport Phenomena in Biological Systems (AC or GE, BB)
- BME 493: Projects in Biomedical Engineering (GE)
- BME 590L: Special Topics with Lab
- BME 791: Graduate Independent Study
- BME 792: Continuation of Graduate Independent Study
- EGR 393: Research Projects in Engineering
In the News
- Two Duke Faculty Have Won the NIH’s Prestigious Pioneer Award (Oct 3, 2022)
- Randles Elected Fellow of National Academy of Inventors (Dec 8, 2021 | Duke Eng…
- The Race to Split a Ventilator (Dec 9, 2020)
- Virtual Reality Blood Flow Simulation To Improve Cardiovascular Interventions (…
- Randles' Cancer Simulations Aims to Be Critical Step Toward Understanding Cance…
- A Revolutionary Picture of Blood Flow Opens New Avenues for Disease Diagnosis a…
- Randles Selected to Help Pilot First U.S. Exascale Computer (Jul 6, 2018 | Prat…
- Duke University Models How and Where Blood flow Impacts Health (Nov 1, 2017)
- Plumbing Virtual Vessels (Sep 21, 2017)
- Supercomputer copies whole-body blood flow (Mar 17, 2016 | BBC News)
- New Collaborative Seed Grant Program Gives Eight Awards (Mar 16, 2016)
- NIH Features Randles Research on Fighting Cancer With Supercomputers (Nov 19, 2…
- Experts put health issues firmly in the spotlight (Sep 14, 2015 | China Daily)
- Amanda Randles: Computing Complex Biological Systems (Jun 5, 2015 | Pratt Schoo…
Representative Publications
- Feiger, Bradley, Christopher W. Jensen, Benjamin S. Bryner, William P. Segars, and Amanda Randles. “Modeling the effect of patient size on cerebral perfusion during veno-arterial extracorporeal membrane oxygenation.” Perfusion, July 3, 2023, 2676591231187962. https://doi.org/10.1177/02676591231187962.
- Roychowdhury, S., E. W. Draeger, and A. Randles. “Establishing metrics to quantify spatial similarity in spherical and red blood cell distributions.” Journal of Computational Science 71 (July 1, 2023). https://doi.org/10.1016/j.jocs.2023.102060.
- Tanade, C., S. Putney, and A. Randles. “Establishing massively parallel models to examine the influence of cell heterogeneity on tumor growth.” Journal of Computational Science 71 (July 1, 2023). https://doi.org/10.1016/j.jocs.2023.102059.
- Shi, Harvey, Madhurima Vardhan, and Amanda Randles. “The Role of Immersion for Improving Extended Reality Analysis of Personalized Flow Simulations.” Cardiovascular Engineering and Technology 14, no. 2 (April 2023): 194–203. https://doi.org/10.1007/s13239-022-00646-y.
- Pepona, M., J. Gounley, and A. Randles. “Effect of constitutive law on the erythrocyte membrane response to large strains.” Computers and Mathematics With Applications 132 (February 15, 2023): 145–60. https://doi.org/10.1016/j.camwa.2022.12.009.