"Nanoscale Construction and Imaging with DNA"
Wednesday, November 1, 2017
12:00 pm - 1:00 pm
Fitzpatrick Center Schiciano Auditorium Side B
Peng Yin, Ph.D.
Please join us Wednesday, November 1st, at 12 pm in Schiciano Auditorium, Side B, as Peng Yin, Ph.D., presents "Nanoscale Construction and Imaging with DNA".Lunch will be served beginning at 11:45 am.Abstract: I'll discuss how to use DNA to construct and visualize nanoscale structures. We have invented a general framework to program DNA/RNA strands to self-assemble into structures with user-specified geometry or dynamics. By interfacing these nanostructures with other functional molecules, we have introduced digital programmability into diverse application areas, e.g. fabrication of inorganic nanoparticles with arbitrary prescribed shapes, robust DNA probes with near optimal binding specificity, RNA-based genetically encodable translation regulators with unprecedented dynamic range and orthogonality, and a highly multiplexed (10× demonstrated), precisely quantitative (>90% precision), and ultra-high resolution (sub-5 nm) optical imaging method. For more details of our work, see http://molecular.systems