Lindsay A. Riley

Education

• M.D. Duke University, School of Medicine, 2026

Positions

• Adjunct Assistant Professor in the Department of Biomedical Engineering

Publications

• Suarez-Arnedo A, Harris M, Robinson C, Riley L, Kim A, Zhang L, et al. Physical continuity at biomaterial-ECM interfaces is associated with reduced fibroblast activation and NF-u03baB signaling. Biomaterials. 2026 Jun;335:124402.
• Riley L, Lee EC, Cheng P, Alvarez DA, Segura T. Metrics for Studying the Porous Void Space of Packed Particles. Particle and Particle Systems Characterization. 2026 Feb 1;43(2).
• Riley L, Lee E, Cheng P, Alvarez DA, Segura T. Metrics for studying the porous void space of packed particles. bioRxiv. 2025 Jul 28;
• Erning K, Wilson KL, Smith CS, Nguyen L, Joesph NI, Irengo R, et al. Delivery of Angiogenic Therapy from Flowable Hyaluronic Acid Porous Scaffolds Results in Functional Improvement without Anti-Inflammatory Agents. Advanced functional materials. 2025 Jul;35(30):2500696.
• Erning K, Wilson KL, Smith CS, Nguyen L, Joesph NI, Irengo R, et al. Clustered VEGF Nanoparticles in Microporous Annealed Particle (MAP) Hydrogel Accelerates Functional Recovery and Brain Tissue Repair after Stroke. bioRxiv. 2025 Feb 5;
• Anderson AR, Caston ELP, Riley L, Nguyen L, Ntekoumes D, Gerecht S, et al. Engineering the microstructure and spatial bioactivity of MAP scaffolds instructs vasculogenesis in vitro and modifies vessel formation in vivo. Advanced functional materials. 2025 Jan;35(3):2400567.
• Whitewolf J, Riley L, Brady B, Grewal G, Segura T, Highley C. Highly porous granular hydrogels reinforced by electrospun hydrogel fibers for long-term stability. bioRxiv. 2024.
• Liu Y, Suarez-Arnedo A, Caston ELP, Riley L, Schneider M, Segura T. Exploring the Role of Spatial Confinement in Immune Cell Recruitment and Regeneration of Skin Wounds. Adv Mater. 2023 Dec;35(49):e2304049.
• Riley L, Cheng P, Segura T. Identification and analysis of 3D pores in packed particulate materials. Nature Computational Science. 2023 Nov 21;3(11):975u201392.
• Liu Y, Suarez-Arnedo A, Riley L, Miley T, Xia J, Segura T. Spatial Confinement Modulates Macrophage Response in Microporous Annealed Particle (MAP) Scaffolds. Advanced healthcare materials. 2023 Oct;12(26):e2300823.
• Riley L, Wei G, Bao Y, Cheng P, Wilson KL, Liu Y, et al. Void Volume Fraction of Granular Scaffolds. Small (Weinheim an der Bergstrasse, Germany). 2023 Oct;19(40):e2303466.
• Anderson A, Caston E, Riley L, Nguyen L, Ntekoumes D, Gerecht S, et al. Engineering the microstructure and spatial bioactivity of MAP scaffolds in vitro instructs neovascularization in vivo. bioRxiv. 2023.
• Daly AC, Riley L, Segura T, Burdick JA. Hydrogel microparticles for biomedical applications. Nature reviews Materials. 2020 Jan;5(1):20u201343.
• Riley L, Schirmer L, Segura T. Granular hydrogels: emergent properties of jammed hydrogel microparticles and their applications in tissue repair and regeneration. Current opinion in biotechnology. 2019 Dec;60:1u20138.
• Riley L, Zhou H, Lange K, Sinsheimer JS, Sehl ME. Determining duration of HER2-targeted therapy using stem cell extinction models. PloS one. 2012 Jan;7(12):e46613.
• Kim S-K, Riley L, Abrol R, Jacobson KA, Goddard WA. Predicted structures of agonist and antagonist bound complexes of adenosine A3 receptor. Proteins. 2011 Jun;79(6):1878u201397.