Biomedical Computation, Automation, & Data Science

Using modeling, simulation, high-performance computing and data analysis to create testable hypotheses about mechanisms driving complex biological functions

Data is becoming the most valuable, actionable resource to advance and personalize medicine, and Duke BME is at the forefront of leveraging biological, chemical, and physiological data to develop the next generation of computational approaches in pharmaceuticals, health, and medicine.

New biomedical imaging and sensing technologies, wearable devices, multi-omics platforms, and electronic health records are generating biomedical data at an unprecedented pace. Researchers in Duke BME are developing innovative data science, artificial intelligence, machine learning, and digital health modeling approaches to transform these multi-scale datasets into actionable health insights. By integrating AI-driven analytics with advanced computational methods, they can uncover patterns, predict outcomes, and accelerate scientific discovery in ways that were previously impossible.

Through computational modeling and simulation, high-performance computing, large-scale data analysis, and AI-enabled prediction and decision-making, Duke BME researchers seek to better understand biological phenomena, identify novel therapeutic targets, and generate testable hypotheses about the mechanisms driving complex biological function. These approaches are helping pave the way for more precise diagnostics, personalized treatments, and data-driven healthcare solutions.

Key Research Areas

  • Computational Modeling of Biological Systems
  • Biomedical & Health Data Sciences
  • Automation
  • AI
colorful rendition of the forces at work within the human vascular system

Our Collaborators

There are extensive collaborations between our BME faculty and Duke University Medical Center clinicians to rapidly translate large-data analysis tools developed at Duke BME for both the patient bedside and broader commercialization.

Affiliated Research Centers

Recent Biomedical Computation, Automation & Data Science News

colorful high-resolution image of a mouse brain
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Associated Faculty

Jessilyn Dunn Profile Photo
Jessilyn Dunn Profile Photo

Jessilyn Dunn

Theodore Kennedy Associate Professor of Biomedical Engineering

Timothy Dunn, Ph.D. Profile Photo
Timothy Dunn, Ph.D. Profile Photo

Timothy Dunn, Ph.D.

Assistant Professor of Biomedical Engineering

Sina Farsiu, Ph.D. Profile Photo
Sina Farsiu, Ph.D. Profile Photo

Sina Farsiu, Ph.D.

Associate Chair for Faculty, Anderson-Rupp Professor of BME

John Hickey Profile Photo
John Hickey Profile Photo

John Hickey

Assistant Professor of Biomedical Engineering

Dr Roarke Horstmeyer Profile Photo
Dr Roarke Horstmeyer Profile Photo

Dr Roarke Horstmeyer

Associate Professor of Biomedical Engineering

Dr Cameron McIntyre, Ph.D. Profile Photo
Dr Cameron McIntyre, Ph.D. Profile Photo

Dr Cameron McIntyre, Ph.D.

Professor of Biomedical Engineering

Mark L. Palmeri Profile Photo
Mark L. Palmeri Profile Photo

Mark L. Palmeri

Professor of the Practice in the Department of Biomedical Engineering

Nimmi Ramanujam, Ph.D. Profile Photo
Nimmi Ramanujam, Ph.D. Profile Photo

Nimmi Ramanujam, Ph.D.

Robert W. Carr, Jr., Distinguished Professor of Biomedical Engineering

Amanda Randles Profile Photo
Amanda Randles Profile Photo

Amanda Randles

Professor of Biomedical Engineering

Dr Daniel Reker Profile Photo
Dr Daniel Reker Profile Photo

Dr Daniel Reker

Assistant Professor of Biomedical Engineering

Dr Phil Romero, Ph.D. Profile Photo
Dr Phil Romero, Ph.D. Profile Photo

Dr Phil Romero, Ph.D.

Associate Professor of Biomedical Engineering

Michael Rubinstein, Ph.D. Profile Photo
Michael Rubinstein, Ph.D. Profile Photo

Michael Rubinstein, Ph.D.

Aleksandar S. Vesic Distinguished Professor

Dr Ophelia Venturelli, Ph.D. Profile Photo
Dr Ophelia Venturelli, Ph.D. Profile Photo

Dr Ophelia Venturelli, Ph.D.

Associate Professor in the Department of Biomedical Engineering

Lingchong You, Ph.D. Profile Photo
Lingchong You, Ph.D. Profile Photo

Lingchong You, Ph.D.

James L. Meriam Distinguished Professor of Biomedical Engineering

Other Research Specialties

Explore additional specialty research areas in Duke BME and throughout the Pratt School of Engineering.