Timothy E Reddy

Timothy E Reddy

Assistant Professor of Biostatistics & Bioinformatics

Appointments and Affiliations

  • Assistant Professor of Biostatistics & Bioinformatics
  • Assistant Professor of Biomedical Engineering
  • Assistant Professor in Molecular Genetics and Microbiology

Contact Information

  • Office Location: 101 Science Drive, 2347 Ciemas, Duke Box 3382, Durham, NC 27708
  • Office Phone: (919) 564-9536
  • Email Address: tim.reddy@duke.edu
  • Websites:

Education

  • Ph.D. Boston University, 2007

Research Interests

Understanding how genetic variation that alters gene regulation contributes to human traits, including risk for common diseases such as diabetes. The Reddy Lab uses an interdisciplinary combination of high-throughput genomics, computational biology, and traditional molecular biology and genetics experiments. We hope that, through our research, we can better understand the gene-regulatory bases for human evolution and human disease. Those findings will likely reveal new pathways of disease that can ultimately be targeted for novel diagnostics and treatment.

Courses Taught

  • CBB 511: Journal Club
  • CBB 591: Independent Study

In the News

Representative Publications

  • Klann, TS; Black, JB; Chellappan, M; Safi, A; Song, L; Hilton, IB; Crawford, GE; Reddy, TE; Gersbach, CA, CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome., Nature Biotechnology, vol 35 no. 6 (2017), pp. 561-568 [10.1038/nbt.3853] [abs].
  • Guo, C; McDowell, IC; Nodzenski, M; Scholtens, DM; Allen, AS; Lowe, WL; Reddy, TE, Transversions have larger regulatory effects than transitions., BMC Genomics, vol 18 no. 1 (2017) [10.1186/s12864-017-3785-4] [abs].
  • Majoros, WH; Campbell, MS; Holt, C; DeNardo, EK; Ware, D; Allen, AS; Yandell, M; Reddy, TE, High-throughput interpretation of gene structure changes in human and nonhuman resequencing data, using ACE., Bioinformatics, vol 33 no. 10 (2017), pp. 1437-1446 [10.1093/bioinformatics/btw799] [abs].
  • Hivert, M-F; Scholtens, DM; Allard, C; Nodzenski, M; Bouchard, L; Brisson, D; Lowe, LP; McDowell, I; Reddy, T; Dastani, Z; Richards, JB; Hayes, MG; Lowe, WL, Genetic determinants of adiponectin regulation revealed by pregnancy, Obesity (Silver Spring, Md.), vol 25 no. 5 (2017), pp. 935-944 [10.1002/oby.21805] [abs].
  • Vockley, CM; Barrera, A; Reddy, TE, Decoding the role of regulatory element polymorphisms in complex disease., Current Opinion in Genetics & Development, vol 43 (2017), pp. 38-45 [10.1016/j.gde.2016.10.007] [abs].