Timothy E Reddy

Reddy

Associate Professor of Biostatistics & Bioinformatics

Appointments and Affiliations

  • Associate Professor of Biostatistics & Bioinformatics
  • Associate Professor in Molecular Genetics and Microbiology

Contact Information

  • Office Location: 101 Science Drive, 2347 Ciemas, Duke Box 3382, Durham, NC 27708
  • Office Phone: (919) 564-9536
  • Email Address: tim.reddy@duke.edu
  • Websites:

Education

  • Ph.D. Boston University, 2007

Research Interests

Understanding how genetic variation that alters gene regulation contributes to human traits, including risk for common diseases such as diabetes. The Reddy Lab uses an interdisciplinary combination of high-throughput genomics, computational biology, and traditional molecular biology and genetics experiments. We hope that, through our research, we can better understand the gene-regulatory bases for human evolution and human disease. Those findings will likely reveal new pathways of disease that can ultimately be targeted for novel diagnostics and treatment.

Courses Taught

  • BIOLOGY 728F: University Program in Genetics and Genomics Biological Solutions Module VI
  • CBB 510S: Computational Biology Seminar
  • CBB 511: Journal Club
  • CBB 591: Independent Study
  • CBB 700: Internship
  • CMB 778F: University Program in Genetics and Genomics Biological Solutions Module VI
  • MGM 778F: University Program in Genetics and Genomics Biological Solutions Module VI
  • UPGEN 778F: University Program in Genetics and Genomics Biological Solutions Module VI

In the News

Representative Publications

  • Kabadi, AM; Machlin, L; Dalal, N; Lee, RE; McDowell, I; Shah, NN; Drowley, L; Randell, SH; Reddy, TE, Epigenome editing of the CFTR-locus for treatment of cystic fibrosis., J Cyst Fibros (2021) [10.1016/j.jcf.2021.04.008] [abs].
  • Kim, Y-S; Johnson, GD; Seo, J; Barrera, A; Cowart, TN; Majoros, WH; Ochoa, A; Allen, AS; Reddy, TE, Correcting signal biases and detecting regulatory elements in STARR-seq data., Genome Res, vol 31 no. 5 (2021), pp. 877-889 [10.1101/gr.269209.120] [abs].
  • Seo, J; Koçak, DD; Bartelt, LC; Williams, CA; Barrera, A; Gersbach, CA; Reddy, TE, AP-1 subunits converge promiscuously at enhancers to potentiate transcription., Genome Res, vol 31 no. 4 (2021), pp. 538-550 [10.1101/gr.267898.120] [abs].
  • Lu, J; Dumitrascu, B; McDowell, IC; Jo, B; Barrera, A; Hong, LK; Leichter, SM; Reddy, TE; Engelhardt, BE, Causal network inference from gene transcriptional time-series response to glucocorticoids., Plos Computational Biology, vol 17 no. 1 (2021) [10.1371/journal.pcbi.1008223] [abs].
  • Black, JB; McCutcheon, SR; Dube, S; Barrera, A; Klann, TS; Rice, GA; Adkar, SS; Soderling, SH; Reddy, TE; Gersbach, CA, Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens., Cell Reports, vol 33 no. 9 (2020) [10.1016/j.celrep.2020.108460] [abs].