Timothy E Reddy

Reddy

Associate Professor of Biostatistics & Bioinformatics

Appointments and Affiliations

  • Associate Professor of Biostatistics & Bioinformatics
  • Associate Professor in Molecular Genetics and Microbiology

Contact Information

  • Office Location: 101 Science Drive, 2347 Ciemas, Duke Box 3382, Durham, NC 27708
  • Office Phone: (919) 564-9536
  • Email Address: tim.reddy@duke.edu
  • Websites:

Education

  • Ph.D. Boston University, 2007

Research Interests

Understanding how genetic variation that alters gene regulation contributes to human traits, including risk for common diseases such as diabetes. The Reddy Lab uses an interdisciplinary combination of high-throughput genomics, computational biology, and traditional molecular biology and genetics experiments. We hope that, through our research, we can better understand the gene-regulatory bases for human evolution and human disease. Those findings will likely reveal new pathways of disease that can ultimately be targeted for novel diagnostics and treatment.

Courses Taught

  • BIOLOGY 728E: University Program in Genetics and Genomics Biological Solutions Module V
  • BIOLOGY 728F: University Program in Genetics and Genomics Biological Solutions Module VI
  • CBB 510S: Computational Biology Seminar
  • CBB 511: Journal Club
  • CBB 591: Independent Study
  • CBB 700: Internship
  • CMB 778E: University Program in Genetics and Genomics Biological Solutions Module V
  • CMB 778F: University Program in Genetics and Genomics Biological Solutions Module VI
  • MGM 778E: University Program in Genetics and Genomics Biological Solutions Module V
  • MGM 778F: University Program in Genetics and Genomics Biological Solutions Module VI
  • UPGEN 778E: University Program in Genetics and Genomics Biological Solutions Module V
  • UPGEN 778F: University Program in Genetics and Genomics Biological Solutions Module VI

In the News

Representative Publications

  • Pickar-Oliver, A; Black, JB; Lewis, MM; Mutchnick, KJ; Klann, TS; Gilcrest, KA; Sitton, MJ; Nelson, CE; Barrera, A; Bartelt, LC; Reddy, TE; Beisel, CL; Barrangou, R; Gersbach, CA, Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells., Nat Biotechnol (2019) [10.1038/s41587-019-0235-7] [abs].
  • Majoros, WH; Kim, Y-S; Barrera, A; Li, F; Wang, X; Cunningham, SJ; Johnson, GD; Guo, C; Lowe, WL; Scholtens, DM; Hayes, MG; Reddy, TE; Allen, AS, Bayesian Estimation of Genetic Regulatory Effects in High-throughput Reporter Assays., Bioinformatics (2019) [10.1093/bioinformatics/btz545] [abs].
  • Lea, AJ; Vockley, CM; Johnston, RA; Del Carpio, CA; Barreiro, LB; Reddy, TE; Tung, J, Genome-wide quantification of the effects of DNA methylation on human gene regulation., Elife, vol 7 (2018) [10.7554/eLife.37513] [abs].
  • Johnson, GD; Barrera, A; McDowell, IC; D'Ippolito, AM; Majoros, WH; Vockley, CM; Wang, X; Allen, AS; Reddy, TE, Human genome-wide measurement of drug-responsive regulatory activity., Nature Communications, vol 9 no. 1 (2018) [10.1038/s41467-018-07607-x] [abs].
  • Majoros, WH; Holt, C; Campbell, MS; Ware, D; Yandell, M; Reddy, TE, Predicting gene structure changes resulting from genetic variants via exon definition features., Bioinformatics, vol 34 no. 21 (2018), pp. 3616-3623 [10.1093/bioinformatics/bty324] [abs].