Timothy E Reddy

Associate Professor of Biostatistics & Bioinformatics,

Appointments and Affiliations

  • Associate Professor of Biostatistics & Bioinformatics,
  • Associate Professor in Molecular Genetics and Microbiology

Contact Information

  • Office Location: 101 Science Drive, 2347 Ciemas, Duke Box 3382, Durham, NC 27708
  • Office Phone: +1 919 564 9536
  • Email Address: tim.reddy@duke.edu
  • Websites:

Education

  • Ph.D. Boston University, 2007

Courses Taught

  • CBB 700: Internship
  • CBB 591: Independent Study
  • CBB 511: Journal Club
  • CBB 510S: Computational Biology Seminar

In the News

Representative Publications

  • Melore, Schuyler M., Marisa C. Hamilton, and Timothy E. Reddy. “HyperCas12a enables highly-multiplexed epigenome editing screens.” BioRxiv, July 9, 2024. https://doi.org/10.1101/2024.07.08.602263.
  • Nussbaum, Daniel P., Colin A. Martz, Andrew M. Waters, Alejandro Barrera, Annie Liu, Justine C. Rutter, Christian G. Cerda-Smith, et al. “Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers.” NPJ Precis Oncol 8, no. 1 (May 31, 2024): 124. https://doi.org/10.1038/s41698-024-00615-9.
  • Yao, David, Josh Tycko, Jin Woo Oh, Lexi R. Bounds, Sager J. Gosai, Lazaros Lataniotis, Ava Mackay-Smith, et al. “Multicenter integrated analysis of noncoding CRISPRi screens.” Nat Methods 21, no. 4 (April 2024): 723–34. https://doi.org/10.1038/s41592-024-02216-7.
  • McCutcheon, Sean R., Adam M. Swartz, Michael C. Brown, Alejandro Barrera, Christian McRoberts Amador, Keith Siklenka, Lucas Humayun, et al. “Transcriptional and epigenetic regulators of human CD8+ T cell function identified through orthogonal CRISPR screens.” Nat Genet 55, no. 12 (December 2023): 2211–23. https://doi.org/10.1038/s41588-023-01554-0.
  • Park, Eunchong, William E. Barclay, Alejandro Barrera, Tzu-Chieh Liao, Harmony R. Salzler, Timothy E. Reddy, Mari L. Shinohara, and Maria Ciofani. “Integrin α3 promotes TH17 cell polarization and extravasation during autoimmune neuroinflammation.” Sci Immunol 8, no. 88 (October 20, 2023): eadg7597. https://doi.org/10.1126/sciimmunol.adg7597.