Teng Su

Assistant Professor in Medicine

Appointments and Affiliations

  • Assistant Professor in Medicine

Contact Information

Education

  • Ph.D. East China University of Science and Technology (China), 2008

Research Interests

My research interests focus on leveraging stem cells and micro- and nano-bioengineering technologies to manipulate and integrate spatiotemporal cues into novel therapeutic platforms that can alter pathological cardiac microenvironment and encourage tissue regeneration.

In the News

Representative Publications

  • Su, Teng, Ke Huang, Kyle G. Mathews, Valery F. Scharf, Shiqi Hu, Zhenhua Li, Brianna N. Frame, et al. “Cardiac Stromal Cell Patch Integrated with Engineered Microvessels Improves Recovery from Myocardial Infarction in Rats and Pigs.” Acs Biomater Sci Eng 6, no. 11 (November 9, 2020): 6309–20. https://doi.org/10.1021/acsbiomaterials.0c00942.
  • Hu, Shiqi, Zhenhua Li, Halle Lutz, Ke Huang, Teng Su, Jhon Cores, Phuong-Uyen Cao Dinh, and Ke Cheng. “Dermal exosomes containing miR-218-5p promote hair regeneration by regulating β-catenin signaling.” Sci Adv 6, no. 30 (July 2020): eaba1685. https://doi.org/10.1126/sciadv.aba1685.
  • Hu, Shiqi, Zhenhua Li, Jhon Cores, Ke Huang, Teng Su, Phuong-Uyen Dinh, and Ke Cheng. “Needle-Free Injection of Exosomes Derived from Human Dermal Fibroblast Spheroids Ameliorates Skin Photoaging.” Acs Nano 13, no. 10 (October 22, 2019): 11273–82. https://doi.org/10.1021/acsnano.9b04384.
  • Huang, K., Z. Li, T. Su, D. Shen, S. Hu, and K. Cheng. “Bispecific Antibody Therapy for Effective Cardiac Repair through Redirection of Endogenous Stem Cells.” Advanced Therapeutics 2, no. 10 (October 1, 2019). https://doi.org/10.1002/adtp.201900009.
  • Qiao, Li, Shiqi Hu, Suyun Liu, Hui Zhang, Hong Ma, Ke Huang, Zhenhua Li, et al. “microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential.” J Clin Invest 129, no. 6 (April 29, 2019): 2237–50. https://doi.org/10.1172/JCI123135.
  • Su, Teng, Ke Huang, Hong Ma, Hongxia Liang, Phuong-Uyen Dinh, Justin Chen, Deliang Shen, et al. “Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury.” Adv Funct Mater 29, no. 4 (January 24, 2019). https://doi.org/10.1002/adfm.201803567.
  • Su, Teng, Ke Huang, Hong Ma, Hongxia Liang, Phuong-Uyen Dinh, Justin Chen, Deliang Shen, et al. “Biomimetics: Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury (Adv. Funct. Mater. 4/2019).” Advanced Functional Materials 29, no. 4 (January 2019): 1970019–1970019. https://doi.org/10.1002/adfm.201970019.
  • Tang, Junnan, Jinqiang Wang, Ke Huang, Yanqi Ye, Teng Su, Li Qiao, Michael Taylor Hensley, et al. “Cardiac cell-integrated microneedle patch for treating myocardial infarction.” Sci Adv 4, no. 11 (November 2018): eaat9365. https://doi.org/10.1126/sciadv.aat9365.
  • Su, Teng, Ke Huang, Michael A. Daniele, Michael Taylor Hensley, Ashlyn T. Young, Junnan Tang, Tyler A. Allen, et al. “Cardiac Stem Cell Patch Integrated with Microengineered Blood Vessels Promotes Cardiomyocyte Proliferation and Neovascularization after Acute Myocardial Infarction.” Acs Appl Mater Interfaces 10, no. 39 (October 3, 2018): 33088–96. https://doi.org/10.1021/acsami.8b13571.
  • Liang, Hongxia, Ke Huang, Teng Su, Zhenhua Li, Shiqi Hu, Phuong-Uyen Dinh, Emily A. Wrona, et al. “Mesenchymal Stem Cell/Red Blood Cell-Inspired Nanoparticle Therapy in Mice with Carbon Tetrachloride-Induced Acute Liver Failure.” Acs Nano 12, no. 7 (July 24, 2018): 6536–44. https://doi.org/10.1021/acsnano.8b00553.
  • Tang, Junnan, Teng Su, Ke Huang, Phuong-Uyen Dinh, Zegen Wang, Adam Vandergriff, Michael T. Hensley, et al. “Targeted repair of heart injury by stem cells fused with platelet nanovesicles.” Nat Biomed Eng 2 (2018): 17–26. https://doi.org/10.1038/s41551-017-0182-x.
  • Su, Teng, Yi Liu, Hongjian He, Jia Li, Yanan Lv, Lili Zhang, Yao Sun, and Chunpu Hu. “Strong Bioinspired Polymer Hydrogel with Tunable Stiffness and Toughness for Mimicking the Extracellular Matrix.” Acs Macro Lett 5, no. 11 (November 15, 2016): 1217–21. https://doi.org/10.1021/acsmacrolett.6b00702.
  • Wang, Xia, Dechao Niu, Pei Li, Qing Wu, Xiaowan Bo, Boji Liu, Song Bao, Teng Su, Huixiong Xu, and Qigang Wang. “Dual-Enzyme-Loaded Multifunctional Hybrid Nanogel System for Pathological Responsive Ultrasound Imaging and T2-Weighted Magnetic Resonance Imaging.” Acs Nano 9, no. 6 (June 23, 2015): 5646–56. https://doi.org/10.1021/nn5068094.
  • Bao, S., D. Wu, T. Su, Q. Wu, and Q. Wang. “Microgels formed by enzyme-mediated polymerization in reverse micelles with tunable activity and high stability.” Rsc Advances 5, no. 55 (January 1, 2015): 44342–45. https://doi.org/10.1039/c5ra02162f.
  • Mao, Yanjie, Teng Su, Qing Wu, Chuanan Liao, and Qigang Wang. “Dual enzymatic formation of hybrid hydrogels with supramolecular-polymeric networks.” Chem Commun (Camb) 50, no. 92 (November 28, 2014): 14429–32. https://doi.org/10.1039/c4cc06472k.
  • Zheng, Xiangning, Dongbei Wu, Teng Su, Song Bao, Chuanan Liao, and Qigang Wang. “Magnetic nanocomposite hydrogel prepared by ZnO-initiated photopolymerization for La (III) adsorption.” Acs Appl Mater Interfaces 6, no. 22 (November 26, 2014): 19840–49. https://doi.org/10.1021/am505177c.
  • Su, T., Z. Tang, H. He, W. Li, X. Wang, C. Liao, Y. Sun, and Q. Wang. “Glucose oxidase triggers gelation of N-hydroxyimide-heparin conjugates to form enzyme-responsive hydrogels for cell-specific drug delivery.” Chemical Science 5, no. 11 (November 1, 2014): 4204–9. https://doi.org/10.1039/c4sc01603c.
  • Wu, Qing, Teng Su, Yanjie Mao, and Qigang Wang. “Thermal responsive microgels as recyclable carriers to immobilize active proteins with enhanced nonaqueous biocatalytic performance.” Chem Commun (Camb) 49, no. 96 (December 14, 2013): 11299–301. https://doi.org/10.1039/c3cc46161k.
  • Su, Teng, Da Zhang, Zhou Tang, Qing Wu, and Qigang Wang. “HRP-mediated polymerization forms tough nanocomposite hydrogels with high biocatalytic performance.” Chem Commun (Camb) 49, no. 73 (September 21, 2013): 8033–35. https://doi.org/10.1039/c3cc44296a.
  • Su, T., G. Y. Wang, S. L. Wang, and C. P. Hu. “Fluorinated siloxane-containing waterborne polyurethaneureas with excellent hemocompatibility, waterproof and mechanical properties.” European Polymer Journal 46, no. 3 (March 1, 2010): 472–83. https://doi.org/10.1016/j.eurpolymj.2009.12.009.
  • Su, T., and C. P. Hu. “Preparation and properties of waterborne interpenetrating polymer networks composed of polyurethaneurea and graft vinyl ester resin.” Journal of Applied Polymer Science 114, no. 2 (October 15, 2009): 1070–79. https://doi.org/10.1002/app.30615.
  • Su, T., G. Y. Wang, and C. P. Hu. “Preparation and properties of well-defined waterborne polyurethaneurea with fluorinated siloxane units in hard or soft segments.” Journal of Polymer Science, Part A: Polymer Chemistry 45, no. 21 (November 1, 2007): 5005–16. https://doi.org/10.1002/pola.22314.
  • Teng, S., G. Y. Wang, X. D. Xu, and P. H. Chun. “Preparation and properties of waterborne polyurethaneurea consisting of fluorinated siloxane units.” Journal of Polymer Science, Part A: Polymer Chemistry 44, no. 10 (May 15, 2006): 3365–73. https://doi.org/10.1002/pola.21425.
  • Su, T., C. Hu, and X. Xu. “Preparation and properties of waterborne polyurethaneurea consisting of α, ω-dihydroxypoly [(3,3,3-trifluoropropyl) methylsiloxane] units.” In “New Century, New Materials and New Life”  Proceedings of 2005 International Conference on Advanced Fibers and Polymer Materials, Icafpm 2005, 1:388–92, 2005.