Mikhail A. Nikiforov

Professor of Pathology

Appointments and Affiliations

  • Professor of Pathology
  • Professor in the Department of Biomedical Engineering
  • Member of the Duke Cancer Institute

Contact Information

  • Office Location: 40 Duke Medicine Circle, Durham, NC 27710
  • Email Address: mikhail.nikiforov@duke.edu

Education

  • B.S. Lomonosov Moscow State University (Russia), 1992
  • M.S. Lomonosov Moscow State University (Russia), 1992
  • Ph.D. University of Illinois, 1997

Courses Taught

  • BME 570L: Introduction to Biomolecular Engineering (GE, BB, MC)

Representative Publications

  • Wolff, David W., Anna Bianchi-Smiraglia, and Mikhail A. Nikiforov. “Compartmentalization and regulation of GTP in control of cellular phenotypes.” Trends Mol Med 28, no. 9 (September 2022): 758–69. https://doi.org/10.1016/j.molmed.2022.05.012.
  • Wolff, David W., Zhiyong Deng, Anna Bianchi-Smiraglia, Colleen E. Foley, Zhannan Han, Xingyou Wang, Shichen Shen, et al. “Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4.” Cell Chem Biol 29, no. 6 (June 16, 2022): 970-984.e6. https://doi.org/10.1016/j.chembiol.2022.01.007.
  • Bianchi-Smiraglia, Anna, and Mikhail A. Nikiforov. “Assessment of Intracellular GTP Levels Using Genetically Encoded Fluorescent Sensors.,” 2394:163–69, 2022. https://doi.org/10.1007/978-1-0716-1811-0_10.
  • Bianchi-Smiraglia, Anna, David W. Wolff, Daniel J. Marston, Zhiyong Deng, Zhannan Han, Sudha Moparthy, Rebecca M. Wombacher, et al. “Author Correction: Regulation of local GTP availability controls RAC1 activity and cell invasion.” Nature Communications 12, no. 1 (November 2021): 6482. https://doi.org/10.1038/s41467-021-26665-2.
  • Bianchi-Smiraglia, Anna, David W. Wolff, Daniel J. Marston, Zhiyong Deng, Zhannan Han, Sudha Moparthy, Rebecca M. Wombacher, et al. “Regulation of local GTP availability controls RAC1 activity and cell invasion.” Nature Communications 12, no. 1 (October 2021): 6091. https://doi.org/10.1038/s41467-021-26324-6.