Joseph A Izatt

Joseph A. Izatt

Michael J. Fitzpatrick Professor of Engineering in the Edmund T. Pratt, Jr. School of Engineering

Biophotonics is concerned with the application of cutting-edge optoelectronic technologies to problems in the biomedical sciences. My research centers on the application of optical technologies for non-invasive, high-resolution imaging and sensing in living biological tissues. The technologies we use in my laboratory include acousto-optic and integrated-optic devices, femtosecond lasers, and ultrabroadband fiber optic telecommunications equipment. The applications of the systems we build include noninvasive medical diagnostics, in-vivo tomographic microscopes, and high-throughput three-dimensional small animal imaging systems for genomics studies. Our work involves multiple collaborations with engineers, biologists, and physicians at Duke and elsewhere.

Appointments and Affiliations

  • Michael J. Fitzpatrick Professor of Engineering in the Edmund T. Pratt, Jr. School of Engineering
  • Professor of Biomedical Engineering
  • Professor in Ophthalmology
  • Faculty Network Member of the Duke Institute for Brain Sciences

Contact Information


  • Ph.D. Massachusetts Institute of Technology, 1991

Research Interests

Professor Izatt's research interests are in the area of biophotonics and include coherence-based biomedical imaging and microscopy, novel technologies for ophthalmic imaging, and nanoscale studies of cellular morphology and dynamics.


Medical Imaging
Medical Diagnostics

Awards, Honors, and Distinctions

  • Fellows. Optical Society of America. 2009
  • Fellow. International Society for Optics and Photonics. 2008
  • Fellows. American Institute for Medical and Biological Engineering. 2007

Courses Taught

  • BME 271: Signals and Systems
  • BME 394: Projects in Biomedical Engineering (GE)
  • BME 436L: Biophotonic Instrumentation (DR)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)

In the News

Representative Publications

  • McNabb, RP; Blanco, T; Bomze, HM; Tseng, HC; Saban, DR; Izatt, JA; Kuo, AN, Method for single illumination source combined optical coherence tomography and fluorescence imaging of fluorescently labeled ocular structures in transgenic mice., Experimental Eye Research (2016) [abs].
  • LaRocca, F; Nankivil, D; DuBose, T; Toth, CA; Farsiu, S; Izatt, JA, In vivo cellular-resolution retinal imaging in infants and children using an ultracompact handheld probe, Nature Photonics (2016) [10.1038/nphoton.2016.141] [abs].
  • Pasricha, ND; Shieh, C; Carrasco-Zevallos, OM; Keller, B; Cunefare, D; Mehta, JS; Farsiu, S; Izatt, JA; Toth, CA; Kuo, AN, Needle Depth and Big-Bubble Success in Deep Anterior Lamellar Keratoplasty: An Ex Vivo Microscope-Integrated OCT Study., Cornea (2016) [abs].
  • Keller, B; Cunefare, D; Grewal, DS; Mahmoud, TH; Izatt, JA; Farsiu, S, Length-adaptive graph search for automatic segmentation of pathological features in optical coherence tomography images., Journal of Biomedical Optics, vol 21 no. 7 (2016) [10.1117/1.JBO.21.7.076015] [abs].
  • Kuo, AN; Verkicharla, PK; McNabb, RP; Cheung, CY; Hilal, S; Farsiu, S; Chen, C; Wong, TY; Ikram, MK; Cheng, CY; Young, TL; Saw, SM; Izatt, JA, Posterior Eye Shape Measurement With Retinal OCT Compared to MRI., Investigative Ophthalmology and Visual Science, vol 57 no. 9 (2016), pp. OCT196-OCT203 [abs].