Greg D. Field
Assistant Professor of Neurobiology
My laboratory studies how the retina processes visual scenes and transmits this information to the brain. We use multi-electrode arrays to record the activity of hundreds of retina neurons simultaneously in conjunction with transgenic mouse lines and chemogenetics to manipulate neural circuit function. We are interested in three major areas. First, we work to understand how neurons in the retina are functionally connected. Second we are studying how light-adaptation and circadian rhythms alter visual processing in the retina. Finally, we are working to understand the mechanisms of retinal degenerative conditions and we are investigating potential treatments in animal models.
Appointments and Affiliations
- Assistant Professor of Neurobiology
- Faculty Network Member of the Duke Institute for Brain Sciences
Contact Information
- Office Location: Bryan Research Building, 311 Research Drive Room 427D, Durham, NC 27710
- Office Phone: (919) 681-7503
- Email Address: field@neuro.duke.edu
Education
- Ph.D. University of Washington, 2004
Research Interests
Study of the retina, using multi-electrode arrays to record retina neuron activity in conjunction with transgenic mouse lines and chemogenetics to manipulate neural circuit function. Field's laboratory is working to understand the mechanisms of retinal degenerative conditions and is investigating potential treatments in animal models.
Courses Taught
- NEUROBIO 393: Research Independent Study
- NEUROBIO 793: Research in Neurobiology
- NEUROBIO 795: Special Topics in Neuroscience
- NEUROSCI 493: Research Independent Study 1
- NEUROSCI 494: Research Independent Study 2
- NEUROSCI 495: Research Independent Study 3
- NEUROSCI 496: Research Independent Study 4
In the News
- Real Neurons are Noisy. Can Neural Implants Figure That Out? (Sep 15, 2020)
- Eyes Have a Natural Version of Night Vision (Sep 13, 2018)
Representative Publications
- Ruda, K; Zylberberg, J; Field, GD, Ignoring correlated activity causes a failure of retinal population codes., Nature Communications, vol 11 no. 1 (2020) [10.1038/s41467-020-18436-2] [abs].
- Cafaro, J; Zylberberg, J; Field, GD, Global Motion Processing by Populations of Direction-Selective Retinal Ganglion Cells., Journal of Neuroscience, vol 40 no. 30 (2020), pp. 5807-5819 [10.1523/JNEUROSCI.0564-20.2020] [abs].
- Wang, T; Pahlberg, J; Cafaro, J; Frederiksen, R; Cooper, AJ; Sampath, AP; Field, GD; Chen, J, Activation of Rod Input in a Model of Retinal Degeneration Reverses Retinal Remodeling and Induces Formation of Functional Synapses and Recovery of Visual Signaling in the Adult Retina., Journal of Neuroscience, vol 39 no. 34 (2019), pp. 6798-6810 [10.1523/JNEUROSCI.2902-18.2019] [abs].
- Kling, A; Field, GD; Brainard, DH; Chichilnisky, EJ, Probing Computation in the Primate Visual System at Single-Cone Resolution., Annu Rev Neurosci, vol 42 (2019), pp. 169-186 [10.1146/annurev-neuro-070918-050233] [abs].
- Field, GD, Circuitry and visual processing in the retinae of mice and men, Investigative Ophthalmology & Visual Science, vol 60 no. 9 (2019) [abs].