Greg D. Field

Greg D. Field

Assistant Professor of Neurobiology

My laboratory studies how the retina processes visual scenes and transmits this information to the brain.  We use multi-electrode arrays to record the activity of hundreds of retina neurons simultaneously in conjunction with transgenic mouse lines and chemogenetics to manipulate neural circuit function. We are interested in three major areas. First, we work to understand how neurons in the retina are functionally connected. Second we are studying how light-adaptation and circadian rhythms alter visual processing in the retina. Finally, we are working to understand the mechanisms of retinal degenerative conditions and we are investigating potential treatments in animal models.

Appointments and Affiliations

  • Assistant Professor of Neurobiology
  • Assistant Professor of Biomedical Engineering
  • Faculty Network Member of the Duke Institute for Brain Sciences

Contact Information

  • Office Location: Bryan Research Building, 311 Research Drive Room 427D, Durham, NC 27710
  • Office Phone: (919) 681-7503
  • Email Address: field@neuro.duke.edu

Education

  • Ph.D. University of Washington, 2004

Research Interests

Study of the retina, using multi-electrode arrays to record retina neuron activity in conjunction with transgenic mouse lines and chemogenetics to manipulate neural circuit function. Field's laboratory is working to understand the mechanisms of retinal degenerative conditions and is investigating potential treatments in animal models.

Courses Taught

  • NEUROBIO 720D: Circuits and Computation
  • NEUROBIO 793: Research in Neurobiology
  • NEUROBIO 795: Special Topics in Neuroscience
  • NEUROSCI 494: Research Independent Study 2
  • NEUROSCI 495: Research Independent Study 3

Representative Publications

  • Yu, W-Q; Grzywacz, NM; Lee, E-J; Field, GD, Cell-type specific changes in retinal ganglion cell function induced by rod death and cone reorganization in rats., Journal of neurophysiology (2017) [10.1152/jn.00826.2016] [abs].
  • Field, GD; Sampath, AP, Behavioural and physiological limits to vision in mammals., Philosophical Transactions B, vol 372 no. 1717 (2017) [10.1098/rstb.2016.0072] [abs].
  • Greschner, M; Heitman, AK; Field, GD; Li, PH; Ahn, D; Sher, A; Litke, AM; Chichilnisky, EJ, Identification of a Retinal Circuit for Recurrent Suppression Using Indirect Electrical Imaging., Current Biology, vol 26 no. 15 (2016), pp. 1935-1942 [10.1016/j.cub.2016.05.051] [abs].
  • Freeman, J; Field, GD; Li, PH; Greschner, M; Gunning, DE; Mathieson, K; Sher, A; Litke, AM; Paninski, L; Simoncelli, EP; Chichilnisky, EJ, Mapping nonlinear receptive field structure in primate retina at single cone resolution., eLife, vol 4 (2015) [10.7554/elife.05241] [abs].
  • Li, PH; Gauthier, JL; Schiff, M; Sher, A; Ahn, D; Field, GD; Greschner, M; Callaway, EM; Litke, AM; Chichilnisky, EJ, Anatomical identification of extracellularly recorded cells in large-scale multielectrode recordings., The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 35 no. 11 (2015), pp. 4663-4675 [10.1523/jneurosci.3675-14.2015] [abs].