Adjunct Associate Professor of Neurobiology
My laboratory studies how the retina processes visual scenes and transmits this information to the brain. We use multi-electrode arrays to record the activity of hundreds of retina neurons simultaneously in conjunction with transgenic mouse lines and chemogenetics to manipulate neural circuit function. We are interested in three major areas. First, we work to understand how neurons in the retina are functionally connected. Second we are studying how light-adaptation and circadian rhythms alter visual processing in the retina. Finally, we are working to understand the mechanisms of retinal degenerative conditions and we are investigating potential treatments in animal models.
Appointments and Affiliations
- Adjunct Associate Professor of Neurobiology
- Faculty Network Member of the Duke Institute for Brain Sciences
Contact Information
- Office Location: Bryan Research Building, 311 Research Drive Room 427D, Durham, NC 27710
- Office Phone: (919) 681-7503
- Email Address: field@neuro.duke.edu
Education
- Ph.D. University of Washington, 2004
Courses Taught
- NEUROBIO 393: Research Independent Study
- NEUROBIO 793: Research in Neurobiology
- NEUROSCI 493: Research Independent Study 1
- NEUROSCI 494: Research Independent Study 2
- NEUROSCI 495: Research Independent Study 3
In the News
- Living Retina Achieves Sensitivity and Efficiency Engineers Can Only Dream Abou…
- Real Neurons are Noisy. Can Neural Implants Figure That Out? (Sep 15, 2020)
- Eyes Have a Natural Version of Night Vision (Sep 13, 2018)
Representative Publications
- Scalabrino, Miranda L., Mishek Thapa, Lindsey A. Chew, Esther Zhang, Jason Xu, Alapakkam P. Sampath, Jeannie Chen, and Greg D. Field. “Robust cone-mediated signaling persists late into rod photoreceptor degeneration.” Elife 11 (August 30, 2022). https://doi.org/10.7554/eLife.80271.
- Roy, Suva, and Greg D. Field. “An optical approach for mapping functional connectivity at single-cell resolution in brain circuits.” Cell Rep Methods 2, no. 8 (August 22, 2022): 100272. https://doi.org/10.1016/j.crmeth.2022.100272.
- Scalabrino, Miranda, Mishek Thapa, Lindsey Chew, Esther Zhang, Jason Xu, A. P. Sampath, Jeannie Chen, and Greg Field. “Robust cone-mediated signaling persists late into rod photoreceptor degeneration.” BioRxiv, 2022. https://doi.org/10.1101/2022.04.27.489758.
- Jun, Na Young, Greg Field, and John Pearson. “Efficient coding, channel capacity and the emergence of retinal mosaics.” BioRxiv, 2022. https://doi.org/10.1101/2022.08.29.505726.
- Ellis, Erika, Antonio Paniagua, Miranda Scalabrino, Mishek Thapa, Jay Rathinavelu, Yuekan Jiao, David Williams, Greg Field, Gordon Fain, and Alapakkam Sampath. “Cones and Cone Pathways Remain Functional in Advanced Retinal Degeneration.” BioRxiv, 2022. https://doi.org/10.1101/2022.09.27.509752.