
Professor in Surgery
Synthetic Virology & Gene Therapy
Appointments and Affiliations
- Professor in Surgery
- Director of Gene Therapy
- Professor of Biomedical Engineering
- Professor of Molecular Genetics and Microbiology
- Affiliate of the Duke Regeneration Center
Contact Information
- Email Address: aravind.asokan@duke.edu
- Websites:
Education
- Ph.D. University of North Carolina - Chapel Hill, 2004
Research Interests
VirologyRNA Biology
Viral Engineering
RNA Engineering
Gene Therapy
Gene Editing
Gene Regulation
Regenerative Medicine
Courses Taught
- BME 493: Projects in Biomedical Engineering (GE)
- BME 494: Projects in Biomedical Engineering (GE)
- BME 791: Graduate Independent Study
- MGM 293: Research Independent Study I
- MGM 593: Research Independent Study
In the News
- Duke Companies and Faculty Share Ideas with Investors at Triangle Venture Day (…
- Gene Therapy for Heart Attacks in Mice Just Got More Precise (Dec 13, 2022)
Representative Publications
- Gonzalez, Trevor J., Aaron Mitchell-Dick, Leo O. Blondel, Marco M. Fanous, Joshua A. Hull, Daniel K. Oh, Sven Moller-Tank, Ruth M. Castellanos Rivera, Jorge A. Piedrahita, and Aravind Asokan. “Structure-guided AAV capsid evolution strategies for enhanced CNS gene delivery.” Nature Protocols, September 21, 2023. https://doi.org/10.1038/s41596-023-00875-y.
- Konkimalla, Arvind, Zachary Elmore, Satoshi Konishi, Lauren Macadlo, Hiroaki Katsura, Aleksandra Tata, Aravind Asokan, and Purushothama Rao Tata. “Efficient Adeno-associated Virus-mediated Transgenesis in Alveolar Stem Cells and Associated Niches.” Am J Respir Cell Mol Biol 69, no. 3 (September 2023): 255–65. https://doi.org/10.1165/rcmb.2022-0424MA.
- Cigliola, Valentina, Adam Shoffner, Nutishia Lee, Jianhong Ou, Trevor J. Gonzalez, Jiaul Hoque, Clayton J. Becker, et al. “Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer.” Nature Communications 14, no. 1 (August 2023): 4857. https://doi.org/10.1038/s41467-023-40486-5.
- Grigsby, Daniel, Mikael Klingeborn, Una Kelly, Lindsey A. Chew, Aravind Asokan, Garth Devlin, Sharon Smith, et al. “AAV Gene Augmentation of Truncated Complement Factor H Differentially Rescues Ocular Complement Dysregulation in a Mouse Model.” Invest Ophthalmol Vis Sci 64, no. 10 (July 3, 2023): 25. https://doi.org/10.1167/iovs.64.10.25.
- Kesseli, S. J., M. K. Krischak, Q. Gao, T. Gonzalez, M. Zhang, S. E. Halpern, R. Kahan, et al. “Adeno-associated virus mediates gene transduction after static cold storage treatment in rodent lung transplantation.” In Journal of Thoracic and Cardiovascular Surgery, 166:e38–49, 2023. https://doi.org/10.1016/j.jtcvs.2022.08.050.