Events

Understanding Environmental Health Effects Among the Most Vulnerable Using Electronic Health Records and Molecular Data

French Family Science Center 4233

My research team leverages data science to tackle previously intractable questions about how social and chemical environmental factors influence health and wellness. Equally important, we collaborate with local organizations and communities to effectively communicate environmental risks, driving actionable solutions that reduce disease burden, save lives, and enhance overall well-being.

National Engineers Week

Pratt School of Engineering

Join Duke's Pratt School of Engineering during this week-long event celebrating how engineers make a difference in our world. More at pratt.duke.edu/e-week

Phage and Robotics-Assisted Directed Evolution

French Family Science Center 4233

Evolution occurs when selective pressures from the environment shape inherited variation over time. Within the laboratory, evolution is commonly used to engineer proteins and RNA, but experimental constraints have limited our ability to reproducibly and reliably explore key factors such as population diversity, the timing of environmental changes, and chance. We developed a high-throughput system […]

Artificial Intelligence for Molecular Design and Elucidation

French Family Science Center 4233

Artificial intelligence and machine learning have become important components of the computational toolbox that can be used to advance chemical research and discovery. Our group has been working on advancing AI/ML as it applies to the broad subfields of synthetic organic chemistry (for developing/discovering reactions), medicinal chemistry (for developing/discovering new functional molecules), and analytical chemistry […]

Multi-Scale Biomechanics of Blood Flow for Vascular Development, Repair, and Rejuvenation

Teer 106

Abstract: During cardiovascular development, peristaltic contraction of the embryonic heart tube produces time-varying hemodynamic forces and pressure gradients across the atrioventricular canal. However, the relative importance of myocardial contraction and hemodynamic force to modulate cardiovascular morphogenesis in the non-Newtonian flow regime remains poorly understood. By developing the 4-D light-sheet fluorescent microscope and post-imaging machine-learning algorithms, […]

Decoding Gene Regulation in 3D and in Single Cells

French Family Science Center 4233

The Leslie lab develops novel computational methods to study cellular biological systems from a global and data-driven perspective. They seek to exploit diverse, high-throughput functional and genomic data to understand the molecular networks underlying fundamental cellular processes, including regulation of transcription, pre-mRNA processing, signaling, and post-transcriptional gene silencing. Today's talk will present recent machine learning […]

From Complete Genomes to Pangenomes: Expanding Our Understanding of Human Haplotype Variation

Bryan Research 103

The initial Human Genome Project was a landmark achievement, serving as an essential resource for basic and clinical science, as well as for understanding human history, for over two decades. However, it is in need of an upgrade due to missing data, inaccurately assembled regions, and its inability to fully represent and identify sequence variants […]

From Gambits to Assurances: Game-Theoretic Integration of Safety and Learning for Human-Centered Robotics

Wilkinson Building, room 130

From autonomous vehicles navigating busy intersections to quadrupeds deployed in household environments, robots must operate safely and efficiently around people in uncertain and unstructured situations. However, today's robots still struggle to robustly handle low-probability events without becoming overly conservative. In this talk, I will discuss how planning in the joint space of physical and information […]

BME Distinguished Seminar Series Kickoff with David Mooney

Wilkinson Building, room 021 auditorium

Join us for a lecture from Professor David Mooney, the Pinkas Family Professor of Bioengineering in the Harvard School of Engineering and Applied Sciences, and a Core Faculty Member of the Wyss Institute. Professor Mooney will present his talk: Matrix Viscoelasticity: Control of Cell Fate to Medical Adhesives Reception to follow.