Laszlo Ormandy Distinguished Professor of Orthopaedic Surgery
Appointments and Affiliations
- Laszlo Ormandy Distinguished Professor of Orthopaedic Surgery
- Professor in Orthopaedic Surgery
- Professor in the Department of Biomedical Engineering
- Affiliate of the Duke Regeneration Center
Contact Information
- Office Location: Room 379, Medical Sciences Research Building, Box 3093 Med. Ctr., Durham, NC 27710
- Office Phone: +1 919 681 9959
- Email Address: lou.defrate@duke.edu
- Websites:
Education
- Sc.D. Massachusetts Institute of Technology, 2005
Courses Taught
- EGR 393: Research Projects in Engineering
- BME 792: Continuation of Graduate Independent Study
- BME 791: Graduate Independent Study
- BME 493: Projects in Biomedical Engineering (GE)
In the News
- Duke Awards 44 Distinguished Professorships (May 4, 2023 | Duke Today)
- Study Shows Men and Women Tear ACL the Same Way In Non-Contact Injury (Apr 18, …
- His and Her Knee Injuries Occur the Same Way (Apr 17, 2018 | US News and World …
- How to prevent knee injuries (Nov 30, 2017 | KSAT News)
- Knee arthritis in Americans has doubled since 1940 (Aug 16, 2017 | Science Maga…
- Athletes: Try this to prevent ACL tears and knee injuries (Aug 9, 2017 | WRAL N…
- Clinical Sciences Day: Collaboration, Mentorship Lead to Science Successes (Oct…
Representative Publications
- Zhao, Q., A. Holt, C. E. Spritzer, L. E. DeFrate, A. L. McNulty, and N. Wang. “High angular resolution diffusion imaging (HARDI) of porcine menisci: a comparison of diffusion tensor imaging and generalized q-sampling imaging.” Quantitative Imaging in Medicine and Surgery 14, no. 4 (April 3, 2024): 2738–46. https://doi.org/10.21037/qims-23-1355.
- Heckelman, Lauren N., Avery L. Kratzer, Charles E. Spritzer, Brian J. Soher, Brian D. Lewis, and Louis E. DeFrate. “Influence of running on femoroacetabular joint bone-to-bone distances.” J Orthop Res 42, no. 4 (April 2024): 837–42. https://doi.org/10.1002/jor.25735.
- Coppock, James A., Nicole E. Zimmer, Charles E. Spritzer, Adam P. Goode, and Louis E. DeFrate. “Automated segmentation and prediction of intervertebral disc morphology and uniaxial deformations from MRI.” Osteoarthr Cartil Open 5, no. 3 (September 2023): 100378. https://doi.org/10.1016/j.ocarto.2023.100378.
- Coppock, James A., Amy L. McNulty, Kathryn N. Porter Starr, Abigail G. Holt, Michael S. Borack, Andrzej S. Kosinski, Amber T. Collins, Connie W. Bales, and Louis E. DeFrate. “The effects of a 6-month weight loss intervention on physical function and serum biomarkers in older adults with and without osteoarthritis.” Osteoarthr Cartil Open 5, no. 3 (September 2023): 100376. https://doi.org/10.1016/j.ocarto.2023.100376.
- Kim-Wang, Sophia Y., Charles E. Spritzer, Kwadwo Owusu-Akyaw, James A. Coppock, Adam P. Goode, Zoë A. Englander, Jocelyn R. Wittstein, and Louis E. DeFrate. “The Predicted Position of the Knee Near the Time of ACL Rupture Is Similar Between 2 Commonly Observed Patterns of Bone Bruising on MRI: Response.” Am J Sports Med 51, no. 8 (July 2023): NP22–24. https://doi.org/10.1177/03635465231172184.