Greg D. Field

Adjunct Associate Professor of Neurobiology

My laboratory studies how the retina processes visual scenes and transmits this information to the brain.  We use multi-electrode arrays to record the activity of hundreds of retina neurons simultaneously in conjunction with transgenic mouse lines and chemogenetics to manipulate neural circuit function. We are interested in three major areas. First, we work to understand how neurons in the retina are functionally connected. Second we are studying how light-adaptation and circadian rhythms alter visual processing in the retina. Finally, we are working to understand the mechanisms of retinal degenerative conditions and we are investigating potential treatments in animal models.

Appointments and Affiliations

  • Adjunct Associate Professor of Neurobiology
  • Faculty Network Member of the Duke Institute for Brain Sciences

Contact Information

  • Office Location: Bryan Research Building, 311 Research Drive Room 427D, Durham, NC 27710
  • Office Phone: +1 919 681 7503
  • Email Address: field@neuro.duke.edu

Education

  • Ph.D. University of Washington, 2004

Courses Taught

  • NEUROSCI 495: Research Independent Study 3
  • NEUROSCI 494: Research Independent Study 2
  • NEUROBIO 793: Research in Neurobiology

In the News

Representative Publications

  • Fleming, Elizabeth A., Greg D. Field, Michael R. Tadross, and Court Hull. “Local synaptic inhibition mediates cerebellar granule cell pattern separation and enables learned sensorimotor associations.” Nat Neurosci 27, no. 4 (April 2024): 689–701. https://doi.org/10.1038/s41593-023-01565-4.
  • Roy, Suva, Xiaoyang Yao, Jay Rathinavelu, and Greg D. Field. “GABAergic Inhibition Controls Receptive Field Size, Sensitivity, and Contrast Preference of Direction Selective Retinal Ganglion Cells Near the Threshold of Vision.” J Neurosci 44, no. 11 (March 13, 2024). https://doi.org/10.1523/JNEUROSCI.1979-23.2023.
  • Dyballa, Luciano, Andra M. Rudzite, Mahmood S. Hoseini, Mishek Thapa, Michael P. Stryker, Greg D. Field, and Steven W. Zucker. “Population encoding of stimulus features along the visual hierarchy.” Proc Natl Acad Sci U S A 121, no. 4 (January 23, 2024): e2317773121. https://doi.org/10.1073/pnas.2317773121.
  • Scalabrino, Miranda L., Mishek Thapa, Tian Wang, Alapakkam P. Sampath, Jeannie Chen, and Greg D. Field. “Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa.” Nat Commun 14, no. 1 (December 12, 2023): 8256. https://doi.org/10.1038/s41467-023-44063-8.
  • Wu, Eric G., Andra M. Rudzite, Martin O. Bohlen, Peter H. Li, Alexandra Kling, Sam Cooler, Colleen Rhoades, et al. “Decomposition of retinal ganglion cell electrical images for cell type and functional inference.” BioRxiv, November 8, 2023. https://doi.org/10.1101/2023.11.06.565889.