Research News

August 15, 2007

See More, Know More

For patients, minimally invasive surgery done through tiny "keyhole" incisions generally means less trauma to the body, less blood loss, smaller surgical scars and less need for pain medication. Surgeons now use optical endoscopes - thin tubes with a tiny video camera--or two-dimensional [...]

August 15, 2007

Feel the Beat

In addition to displaying cardiac anatomy, various medical imaging techniques -- including PET, CT, MRI and echocardiography provide information related to heart function. However, the potential complications with the use of contrast agents as well as the cost of these imaging methods are limiting [...]

August 15, 2007

Probing the Living Cell

Nanotechnology is offering up new methods to unravel the workings of the tiny human cell -- the basic building block of our body’s tissues. Think of poking a hole in a cell and sticking in a flashlight. Tuan Vo-Dinh A unique nanobiosensor developed by Duke biomedical engineering Professor Tuan Vo [...]

August 15, 2007

DNA, a la carte

In 2007, the U.S. Food and Drug Administration approved the first human vaccine to offer protection against the H5N1 influenza virus, commonly known as avian or bird flu. Yet, in the event that a viral strain began spreading from human to human, the vaccine is expected to provide only limited [...]

August 15, 2007

Reigning in HIV/AIDS

An estimated 12,000 people contract the AIDS virus each day, including a disproportionate number of women. Microbicides might help protect at-risk women by serving as "molecular condoms"--physical barriers or filters with HIV-neutralizing ingredients that slow viral passage from semen into body [...]

August 15, 2007

Drug Depot

Osteoarthritis--a degenerative joint disease that affects 21 million people in the U.S. and is the nation's leading cause of disability--had been attributed primarily to the gradual wear and tear of joint surfaces. More recently, scientists have discovered that inflammation sparked by the immune [...]

August 15, 2007

Drugs that Deliver

Chemotherapy often falls short of achieving its full impact because the drugs diffuse in and out of tumors too rapidly. That's because the small size of current chemotherapy drugs -- which typically have a molecular weight in the 300 to 600 range -- allow them to be readily excreted through the [...]

August 15, 2007

Special Delivery

Gene therapy is a promising approach for treating many genetic disorders, particularly those such as hemophilia and some metabolic diseases, in which a missing or dysfunctional gene fails to provide a protein required for normal bodily functions. However, the therapeutic potential of gene therapy [...]

August 15, 2007

Ultrasound Solution

Many major diseases of the liver cause the organ to stiffen over time due to scarring, a condition known as fibrosis. Ultimately, such disorders--including hepatitis and fatty liver disease--can lead to cirrhosis, in which scarred tissue becomes an obstacle to blood flow and liver function. Today [...]

July 30, 2007

Duke Scientists to Explore Networks and Systems of Biology

DURHAM, N.C. -- The National Institute for General Medical Sciences has awarded Duke University a $14.5 million, five-year grant to establish a new national center for systems biology in the Duke Institute for Genome Sciences & Policy (IGSP).